Zobrazeno 1 - 10
of 79
pro vyhledávání: '"A N, Shuvaev"'
Autor:
Olga S. Belozor, Alex A. Vasilev, Alexandra G. Mileiko, Liudmila D. Mosina, Ilya G. Mikhailov, Andrey N. Shuvaev, Anton N. Shuvaev
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 18, Iss 1, Pp 63-71 (2024)
Introduction. Memantine is an agent that used for treatment of Alzheimer's type dementia. Memantine considerably reduces the effects of neurodegeneration, may potentially slow down the neurodegenerative changes in the cerebellum and may act as treatm
Externí odkaz:
https://doaj.org/article/1cbf8f676e0d45fab536ed3a7aa3b50d
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 16, Iss 2, Pp 58-69 (2022)
Cerebellar degeneration remains a poorly studied topic. Excitotoxicity, i.e. neuronal damage and death due to excess activation of postsynaptic N-methyl-D-aspartate receptors (NMDAR) by glutamate, is considered to be a universal mechanism of most neu
Externí odkaz:
https://doaj.org/article/db79675b49c242fa8078d0fa532aed23
Autor:
Аnton N. Shuvaev, Оlga S. Belozor, Oleg I. Mozjei, Daria A. Yakovleva, Аndrey N. Shuvaev, Marina V. Smolnikova, Еlena A. Pozhilenkova, S. . Каsparov, Vladimir V. Salmin, Аlla B. Salmina
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 15, Iss 1, Pp 51-58 (2021)
Introduction. Synaptic plasticity is impaired in the early stages of a neurodegenerative process but is potentially reversible. The study of mechanisms associated with synaptic plasticity in neurodegenerative cerebellar conditions has enabled the sea
Externí odkaz:
https://doaj.org/article/ea26d6fd571b480d84300aad0032662c
Autor:
Anton N. Shuvaev, Olga S. Belozor, Oleg Mozhei, Dariya A. Yakovleva, Ilya V. Potapenko, Andrey N. Shuvaev, Marina V. Smolnikova, Vladimir V. Salmin, Alla B. Salmina, Hirokazu Hirai, Anja G. Teschemacher, Sergey Kasparov
Publikováno v:
Neurobiology of Disease, Vol 154, Iss , Pp 105340- (2021)
Bergmann glia (BG) are highly specialized radial astrocytes of the cerebellar cortex, which play a key role in the uptake of synaptic glutamate via the excitatory amino acid transporter EAAT1. Multiple lines of evidence suggest that in cerebellar neu
Externí odkaz:
https://doaj.org/article/42b772dd45154454a13f5eaf63bcdd32
Autor:
A. N. Shuvaev, O. S. Belozor, M. V. Smolnikova, D. A. Yakovleva, Andr. N. Shuvaev, O. M. Kazantseva, E. A. Pozhilenkova, O. I. Mozhei, S. Kasparov
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 23, Iss 4, Pp 473-481 (2019)
Hereditary disorders of the neuronal system are some of the most important problems of medicine in the XXI century. The most interesting representatives of this group are highly prevalent polyglutamine spinocerebellar ataxias (SCAs). It has a basemen
Externí odkaz:
https://doaj.org/article/0d76f6eeb038483aaf6b705e05b4d232
Autor:
Anton N. Shuvaev, Olga S. Belozor, Oleg I. Mozhei, Andrey N. Shuvaev, Yana V. Fritsler, Elena D. Khilazheva, Angelina I. Mosyagina, Hirokazu Hirai, Anja G. Teschemacher, Sergey Kasparov
Publikováno v:
Cells, Vol 11, Iss 14, p 2247 (2022)
Spinocerebellar ataxia type 1 (SCA1) is an intractable progressive neurodegenerative disease that leads to a range of movement and motor defects and is eventually lethal. Purkinje cells (PC) are typically the first to show signs of degeneration. SCA1
Externí odkaz:
https://doaj.org/article/8f7a91ade2ed458e865a3f3e101ce80b
Autor:
Anton N. Shuvaev, Olga S. Belozor, Oleg I. Mozhei, Aleksandra G. Mileiko, Ludmila D. Mosina, Irina V. Laletina, Ilia G. Mikhailov, Yana V. Fritsler, Andrey N. Shuvaev, Anja G. Teschemacher, Sergey Kasparov
Publikováno v:
Brain Sciences, Vol 12, Iss 4, p 495 (2022)
Memantine is an FDA approved drug for the treatment of Alzheimer’s disease. It reduces neurodegeneration in the hippocampus and cerebral cortex through the inhibition of extrasynaptic NMDA receptors in patients and mouse models. Potentially, it cou
Externí odkaz:
https://doaj.org/article/d1c2b4b6c0b844ec9ee9aae15d4c2b20
Autor:
E. V. Lychkovskaya, A. N. Shuvaev, G. E. Gercog, L. V. Trufanova, L. B. Shadrina, A. A. Semenchukov, A. B. Salmina
Publikováno v:
Бюллетень сибирской медицины, Vol 17, Iss 1, Pp 191-198 (2018)
In the process of evolution of eukaryotes has formatted a highly organized mechanism for maintaining and regulating intracellular calcium homeostasis, which is one of the most important components of cell signaling in all branches of the phylogenetic
Externí odkaz:
https://doaj.org/article/b6b6a71ff7984275a295c4211f5f9232
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 9, Iss 4, Pp 54-58 (2017)
The patch-clamp (PC) technique is the gold standard in studyingprocesses that occur on the membranes of excitable cells,both in the physiological condition and in pathology. However,gaining this unique information is associated with certain difficult
Externí odkaz:
https://doaj.org/article/9e10290534db47eda325c4fdd821ca85
Autor:
E. A. Teplyashina, Ya. V. Gorina, E. D. Khilazheva, E. B. Boytsova, A. I. Mosyagina, N. A. Malinovskaya, Yu. K. Komleva, A. V. Morgun, Yu. A. Uspenskaya, A. N. Shuvaev, A. B. Salmina
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 58:728-741
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a217ea881e8ef10fb5e8fd853f694d3e
https://doi.org/10.1134/s0022093022030097
https://doi.org/10.1134/s0022093022030097