Zobrazeno 1 - 10
of 69
pro vyhledávání: '"A N, Saprin"'
Publikováno v:
Biochemistry (Moscow). 73:1493-1510
Among the key antioxidant enzymes, thioredoxin and glutaredoxin systems play an important role in cell defense against oxidative stress and maintenance of redox homeostasis owing to the regulation of thiol-disulfide exchange. The thioredoxin isoforms
Autor:
N. N. Chernov, Elena Kalinina, Ya. N. Kotova, N. P. Scherbak, V. S. Solomka, A. N. Saprin, Ya. A. Andreev
Publikováno v:
Biochemistry (Moscow). 71:1200-1206
The relationship between expression of genes encoding key antioxidant enzymes, heme oxygenase-1, Bcl-2, and Bcl-xl and change in production of reactive oxygen species (ROS) resulting from development of resistance of cancer cells K562, MCF-7, and SKO
Autor:
V. S. Solomka, N. P. Shcherbak, Elena Kalinina, Ya. N. Kotova, A. N. Saprin, V. A. Serezhenkov
Publikováno v:
Biophysics. 51:435-439
The free-radical state of K562 human erythroleukemia cells changes during the development of resistance to doxorubicin, an antitumor antibiotic with prooxidant action widely used in oncology. It was found that the level of superoxide anion in the res
Publikováno v:
Pharmaceutical Chemistry Journal. 38:347-354
Publikováno v:
Human Physiology. 30:435-440
The role of the metabolic status of the donor and the recipient in graft survival was studied with skin grafting between genetically different mouse strains (BALB/C, C3HA, DBA/2, and C57Bl/6). It was concluded that the donor must have a lower metabol
Publikováno v:
Biology Bulletin of the Russian Academy of Sciences. 29:115-119
We studied intraspecific features of the main enzymes of metabolism and detoxication of xenobiotics on mice (eight inbred lines) and rats (five lines) for estimation of possible variants of complete or incomplete metabolic equality. Significant genet
Publikováno v:
Human Physiology. 26:224-231
Analysis of the literature concerning the possibilities of predicting the risk of the development of pathological processes based on the polymorphism of the enzymes of metabolism and detoxification of xenobiotics (EMDX)—cytochrome P-450, glutathion
Publikováno v:
Doklady Biological Sciences. 388:35-37
Publikováno v:
Doklady Biochemistry and Biophysics. 377:72-74
Publikováno v:
Vestnik Rossiiskoi akademii meditsinskikh nauk. (3)
Reduced glutathione (GSH), gamma-glutamyl-L-cysteineglycine, is a tripeptide widespread in plants, animals, and man as a low-molecular weight SH-containing compound. This review presents results of published and original studies concerned with the sy