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A welcome addition to the therapeutic armamentarium against colorectal cancer

Autor: Amol N. Rakkar

Publikováno v: Community Oncology. 4:123-125

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce6348dc30a17cad6507b5a7662b7d23
https://doi.org/10.1016/s1548-5315(11)70068-7

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Promoting apoptosis: a novel activity associated with the cyclin-dependent kinase inhibitor p27

Autor: Y, Katayose, M, Kim, A N, Rakkar, Z, Li, K H, Cowan, P, Seth

Publikováno v: Cancer research. 57(24)

p27Kip1, a cyclin-dependent kinase inhibitor, is recognized as a negative regulator of the cell cycle. In this paper, we report that overexpression of p27Kip1 triggers apoptosis in several different human cancer cell lines. Using a recombinant adenov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b696fc380202a0fa8d13979a86ba9a6b
https://pubmed.ncbi.nlm.nih.gov/9407946

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A recombinant adenovirus expressing wild type p53 induces apoptosis in drug-resistant human breast cancer cells: a gene therapy approach for drug-resistant cancers

Autor: P, Seth, D, Katayose, Z, Li, M, Kim, R, Wersto, C, Craig, N, Shanmugam, E, Ohri, B, Mudahar, A N, Rakkar, P, Kodali, K, Cowan

Publikováno v: Cancer gene therapy. 4(6)

The cytotoxicity of a recombinant adenovirus expressing the wild type tumor suppressor gene p53 (AdWTp53) was studied in two human breast cancer MCF-7 sublines selected for resistance to adriamycin (MCF-Adr) and mitoxantrone (MCF-Mito). Although the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9e5163f76b0440d3409f90f17e0f985b
https://pubmed.ncbi.nlm.nih.gov/9408609

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