Zobrazeno 1 - 10
of 52
pro vyhledávání: '"A N, Pouliopoulos"'
Autor:
Chris Payne, Paul Cressey, Anisia Talianu, Elwira Szychot, Darren Hargrave, Maya Thanou, Antonios N. Pouliopoulos
Publikováno v:
Heliyon, Vol 10, Iss 22, Pp e39972- (2024)
Focused ultrasound-mediated opening of the blood-brain barrier offers a great opportunity to deliver therapeutics into hard-to-treat brain tumors such as glioblastoma multiforme or diffuse midline glioma. However, the potential of the technique to of
Externí odkaz:
https://doaj.org/article/6208721f36a949838f4b41e144bc9268
Autor:
Dong Liu, Fabian Munoz, Soroosh Sanatkhani, Antonios N. Pouliopoulos, Elisa E. Konofagou, Jack Grinband, Vincent P. Ferrera
Publikováno v:
Brain Stimulation, Vol 16, Iss 4, Pp 1196-1204 (2023)
Background: Focused ultrasound (FUS) is a non-invasive neuromodulation technology that is being investigated for potential treatment of neurological and psychiatric disorders. FUS combined with microbubbles can temporarily open the intact blood-brain
Externí odkaz:
https://doaj.org/article/db89d3f2e07148d3ba70d7cad55d39b3
Autor:
R. L. Noel, A. J. Batts, R. Ji, A. N. Pouliopoulos, S. Bae, A. R. Kline-Schoder, E. E. Konofagou
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Focused Ultrasound (FUS) paired with systemically-injected microbubbles (μB) is capable of transiently opening the blood–brain barrier (BBBO) for noninvasive and targeted drug delivery to the brain. FUS-BBBO is also capable of modulating
Externí odkaz:
https://doaj.org/article/d82c19aa9ee34e57904e62094b044d41
Autor:
Weiqi Zhang, Hilde Metzger, Stavros Vlatakis, Amelia Claxton, M. Alejandra Carbajal, Leong Fan Fung, James Mason, K.L. Andrew Chan, Antonios N. Pouliopoulos, Roland A. Fleck, Paul Prentice, Maya Thanou
Publikováno v:
Ultrasonics Sonochemistry, Vol 97, Iss , Pp 106445- (2023)
Phase-change nanodroplets have attracted increasing interest in recent years as ultrasound theranostic nanoparticles. They are smaller compared to microbubbles and they may distribute better in tissues (e.g. in tumours). They are composed of a stabil
Externí odkaz:
https://doaj.org/article/3d3ca582849e479a88f6cfdf23ea227b
Autor:
Antonios N. Pouliopoulos, Maria F. Murillo, Rebecca Lynn Noel, Alec J. Batts, Robin Ji, Nancy Kwon, Han Yu, Chi-Kun Tong, Jennifer N. Gelinas, Dion Khodagholy Araghy, S. Abid Hussaini, Elisa E. Konofagou
Publikováno v:
Brain Stimulation, Vol 15, Iss 4, Pp 927-941 (2022)
Optogenetics has revolutionized the capability of controlling genetically modified neurons in vitro and in vivo and has become an indispensable neuroscience tool. Using light as a probe for selective neuronal activation or inhibition and as a means t
Externí odkaz:
https://doaj.org/article/497835ba9f244d288956bd3d545c3794
Autor:
Antonios N. Pouliopoulos, Nancy Kwon, Greg Jensen, Anna Meaney, Yusuke Niimi, Mark T. Burgess, Robin Ji, Alicia J. McLuckie, Fabian A. Munoz, Hermes A. S. Kamimura, Andrew F. Teich, Vincent P. Ferrera, Elisa E. Konofagou
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract An emerging approach with potential in improving the treatment of neurodegenerative diseases and brain tumors is the use of focused ultrasound (FUS) to bypass the blood–brain barrier (BBB) in a non-invasive and localized manner. A large bo
Externí odkaz:
https://doaj.org/article/a8810ff79a67460bb0d1b9296c6a333f
Autor:
Zachary K. Englander, Hong-Jian Wei, Antonios N. Pouliopoulos, Ethan Bendau, Pavan Upadhyayula, Chia-Ing Jan, Eleanora F. Spinazzi, Nina Yoh, Masih Tazhibi, Nicholas M. McQuillan, Tony J. C. Wang, Jeffrey N. Bruce, Peter Canoll, Neil A. Feldstein, Stergios Zacharoulis, Elisa E. Konofagou, Cheng-Chia Wu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Drug delivery in diffuse intrinsic pontine glioma is significantly limited by the blood-brain barrier (BBB). Focused ultrasound (FUS), when combined with the administration of microbubbles can effectively open the BBB permitting the entry of
Externí odkaz:
https://doaj.org/article/e7a089d62acc48338378a525c21513c4
Publikováno v:
Ultrasound in Medicine & Biology. 49:908-917
Optogenetics employs engineered viruses to genetically modify cells to express specific light-sensitive ion channels. The standard method for gene delivery in the brain involves invasive craniotomies that expose the brain and direct injections of vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0f2bd5ec7592b41d9a91fa3cc87798
https://doi.org/10.1016/j.ultrasmedbio.2022.11.002
https://doi.org/10.1016/j.ultrasmedbio.2022.11.002
Publikováno v:
IEEE Transactions on Biomedical Engineering. :1-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d225b9b1f5ac544c7c205d3d897b49e3
https://doi.org/10.1109/tbme.2023.3266952
https://doi.org/10.1109/tbme.2023.3266952
Autor:
Antonios N. Pouliopoulos, Daniella A. Jimenez, Alexander Frank, Alexander Robertson, Lin Zhang, Alina R. Kline-Schoder, Vividha Bhaskar, Mitra Harpale, Elizabeth Caso, Nicholas Papapanou, Rachel Anderson, Rachel Li, Elisa E. Konofagou
Publikováno v:
Frontiers in Physics, Vol 8 (2020)
Non-invasive blood-brain barrier (BBB) opening using focused ultrasound (FUS) is being tested as a means to locally deliver drugs into the brain. Such FUS therapies require injection of pre-formed microbubbles, currently used as contrast agents in ul
Externí odkaz:
https://doaj.org/article/70881aa594b9495d87ff24a135fb0bfc