Zobrazeno 1 - 10
of 122
pro vyhledávání: '"A N, Osipenko"'
Autor:
Mark B. Plotnikov, Galina A. Chernysheva, Vera I. Smol’yakova, Oleg I. Aliev, Anna M. Anishchenko, Olga A. Ulyakhina, Eugene S. Trofimova, Anastasia A. Ligacheva, Nina D. Anfinogenova, Anton N. Osipenko, Anastasia R. Kovrizhina, Andrei I. Khlebnikov, Igor A. Schepetkin, Anastasia G. Drozd, Evgenii V. Plotnikov, Dmitriy N. Atochin, Mark T. Quinn
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1057 (2023)
The activation of c-Jun N-terminal kinase (JNK) plays an important role in stroke outcomes. Tryptanthrin-6-oxime (TRYP-Ox) is reported to have high affinity for JNK and anti-inflammatory activity and may be of interest as a promising neuroprotective
Externí odkaz:
https://doaj.org/article/f8e06b8fec7049568f7fbab52351270e
Autor:
A. N. Osipenko
Publikováno v:
Acta Biomedica Scientifica, Vol 6, Iss 2, Pp 70-80 (2021)
The review describes a number of competing views on the main causes of cholesterol accumulation in atherosclerotic vessels. On the one hand, unregulated cholesterol influx into arterial intima is primarily related to the increasing proportion of athe
Externí odkaz:
https://doaj.org/article/f20aee7afb894045b82d4d2f8fa90a55
Autor:
Mark B. Plotnikov, Galina A. Chernysheva, Vera I. Smol’yakova, Oleg I. Aliev, Tatyana I. Fomina, Lyubov A. Sandrikina, Irina V. Sukhodolo, Vera V. Ivanova, Anton N. Osipenko, Nina D. Anfinogenova, Andrei I. Khlebnikov, Dmitriy N. Atochin, Igor A. Schepetkin, Mark T. Quinn
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 714 (2023)
Activation of c-Jun N-terminal kinases (JNKs) is involved in myocardial injury, left ventricular remodeling (LV), and heart failure (HF) after myocardial infarction (MI). The aim of this research was to evaluate the effects of a selective JNK inhibit
Externí odkaz:
https://doaj.org/article/216f2644432a467b9703cf6cf31007dc
Autor:
Igor A. Schepetkin, Galina A. Chernysheva, Oleg I. Aliev, Liliya N. Kirpotina, Vera I. Smol’yakova, Anton N. Osipenko, Mark B. Plotnikov, Anastasia R. Kovrizhina, Andrei I. Khlebnikov, Evgenii V. Plotnikov, Mark T. Quinn
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2119 (2022)
The c-Jun N-terminal kinases (JNKs) regulate many physiological processes, including inflammatory responses, morphogenesis, cell proliferation, differentiation, survival, and cell death. Therefore, JNKs represent attractive targets for therapeutic in
Externí odkaz:
https://doaj.org/article/954dadc088984656bafaaa8b1ac9138c
Publikováno v:
Бюллетень сибирской медицины, Vol 16, Iss 1, Pp 65-72 (2017)
Aim. The aim of our study is to explore the mechanisms of neuroprotective effects of p-tyrosol in acute global cerebral ischemia-reperfusion in rats.Material and methods. The study was performed on 30 male rats stock Wistar (250–300 g).Animals were
Externí odkaz:
https://doaj.org/article/7c0a2eeadf8e403abeb969be0bb30f60
Publikováno v:
Bulletin of Experimental Biology and Medicine. 173:17-20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a966396d9ed529a5a6cfb21a5815e40c
https://doi.org/10.1007/s10517-022-05483-6
https://doi.org/10.1007/s10517-022-05483-6
Autor:
Mark B. Plotnikov, Galina A. Chernysheva, Vera I. Smolyakova, Oleg I. Aliev, Eugene S. Trofimova, Eugene Y. Sherstoboev, Anton N. Osipenko, Andrei I. Khlebnikov, Yana J. Anfinogenova, Igor A. Schepetkin, Dmitriy N. Atochin
Publikováno v:
Cells, Vol 9, Iss 8, p 1860 (2020)
A novel specific inhibitor of c-Jun N-terminal kinase, 11H-indeno[1,2-b]quinoxalin-11-one oxime sodium salt (IQ-1S), has a high affinity to JNK3 compared to JNK1/JNK2. The aim of this work was to study the mechanisms of neuroprotective activity of IQ
Externí odkaz:
https://doaj.org/article/3dc1138880274ce18240f8c48e38d1e9
Autor:
Mark B. Plotnikov, Galina A. Chernysheva, Oleg I. Aliev, Vera I. Smol’iakova, Tatiana I. Fomina, Anton N. Osipenko, Victoria S. Rydchenko, Yana J. Anfinogenova, Andrei I. Khlebnikov, Igor A. Schepetkin, Dmitriy N. Atochin
Publikováno v:
Molecules, Vol 24, Iss 9, p 1722 (2019)
c-Jun N-terminal kinase (JNK) is activated by various brain insults and is implicated in neuronal injury triggered by reperfusion-induced oxidative stress. Some JNK inhibitors demonstrated neuroprotective potential in various models, including cerebr
Externí odkaz:
https://doaj.org/article/d24544c34061450fbb53ff16f4a2156d
Autor:
Galina A. Chernysheva, T. M. Plotnikova, V. I. Smol’yakova, I. Yu. Chukicheva, Anton N. Osipenko, A. V. Kutchin
Publikováno v:
Bulletin of Experimental Biology and Medicine. 169:310-313
2,6-Diisobornyl-4-methylphenol (Dibornol, 10 mg/kg intragastrically daily for 5 days after myocardial ischemia/reperfusion) 1.5-fold increased rat survival during the acute post-infarction period in comparison with the control group. In survivors, Di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7afdb73c7839c36916eba41b97c34247
https://doi.org/10.1007/s10517-020-04876-9
https://doi.org/10.1007/s10517-020-04876-9
Autor:
Alexander N. Osipenko
Publikováno v:
International Journal of Biomedicine, Vol 2, Iss 4, Pp 291-295 (2012)
The aim of this study was to assess the fatty acid balance in the blood plasma, in the fragments of the intact vessels and the vessels showing signs of atherosclerosis.Material and Methods: The article presents the results of the examination of the b
Externí odkaz:
https://doaj.org/article/ff889e667fa544da96f641bb783b71bb