Zobrazeno 1 - 10
of 40
pro vyhledávání: '"A N, Gratchev"'
Autor:
Olga V. Kovaleva, Polina A. Podlesnaya, Ekaterina S. Kudinova, Valeria V. Mochalnikova, Nikolay E. Kushlinskii, Alexey N. Gratchev
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 52, Iss 4, Pp 189-196 (2024)
Rationale: Long non-coding RNAs (lncRNAs) influence tumor cell properties during the onset and progression of lung malignancies; however, their diagnostic and prognostic significance has not been determined. We have previously shown that when non-sma
Externí odkaz:
https://doaj.org/article/ffe96e95ecd94f978e550508008dc21d
Autor:
I. S. Stilidi, O. V. Kovaleva, A. N. Gratchev, E. M. Tchevkina, P. A. Podlesnaya, P. V. Tsarapaev, E. A. Suleymanov, N. E. Kushlinskii
Publikováno v:
Бюллетень сибирской медицины, Vol 21, Iss 3, Pp 96-104 (2022)
Background. Implementation of immunotherapy in clinical oncological practice has significantly improved the results of cancer treatment. It resulted in the need for seeking new markers to assess the effectiveness of therapy and the disease prognosis.
Externí odkaz:
https://doaj.org/article/0eebef41557c48d7b1cd4982a01e79c9
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 50, Iss 1, Pp 13-20 (2022)
Macrophages, natural killers and T cells play the central role in tumor cells destruction. The purpose of this review is to summarize the state-of-the-art perspectives of the interplay between tumor cells and tumor stroma leading both to the formatio
Externí odkaz:
https://doaj.org/article/8b2bfbbe24a34442bbfa89b56b6a6e1b
Autor:
P. A. Podlesnaya, O. V. Kovaleva, M. A. Rashidova, D. V. Samoilova, A. A. Petrenko, V. V. Mochalnikova, A. N. Gratchev
Publikováno v:
Успехи молекулярной онкологии, Vol 9, Iss 1, Pp 8-19 (2022)
Introduction. Prostate cancer is by far the most frequently diagnosed cancer among the male population and ranks fifth in the world in terms of mortality rates among malignant neoplasms. Today it is known that the tumor microenvironment plays an impo
Externí odkaz:
https://doaj.org/article/204b4f01abde4f88a5347f86bf86b1fc
Autor:
O. V. Kovaleva, M. A. Rashidova, P. A. Podlesnaya, D. V. Samoilova, V. V. Mochalnikova, A. N. Gratchev
Publikováno v:
Успехи молекулярной онкологии, Vol 8, Iss 4, Pp 67-74 (2021)
Introduction. Non-small cell lung cancer is a common cancer with a poor prognosis. Modern researchers conduct many studies devoted to understanding the molecular mechanisms of its pathogenesis. Modern advances in immunotherapy have significantly impr
Externí odkaz:
https://doaj.org/article/056de8616cef4f238aa5290e4ec413d1
Autor:
Olga V. Kovaleva, Polina A. Podlesnaya, Alexei N. Gratchev, Viktor L. Chang, Nikolai A. Ognerubov, Nikolai E. Kushlinskii
Publikováno v:
Современная онкология, Vol 23, Iss 1, Pp 122-127 (2021)
Stomach cancer is one of the most common tumors of the gastrointestinal tract. In Russia, stomach cancer is ranked fourth in incidence among malignancies and gives ground for lung, breast and colon cancers. Although the success of PD-1/PD-L1 inhibito
Externí odkaz:
https://doaj.org/article/e415a458b020461d865ff5e5ab64b4b7
Autor:
O. V. Kovaleva, O. V. Rashidova, V. V. Mochalnikova, D. V. Samoilova, P. A. Podlesnaya, A. N. Gratchev
Publikováno v:
Успехи молекулярной онкологии, Vol 8, Iss 2 (2021)
Introduction. Cancer of the esophagus ranks sixth in mortality among malignant neoplastic diseases. To understand the molecular mechanisms of its progression, it is necessary to study not only tumor cells directly, but also cells of the microenvironm
Externí odkaz:
https://doaj.org/article/85cd90da62dd463491c2fe2477c41b36
Publikováno v:
Успехи молекулярной онкологии, Vol 5, Iss 4, Pp 20-28 (2019)
Macrophages are the key cells of the innate immune system. One of the main functions of macrophages is the regulation of inflammation. Being common in all tissues and organs of the human body, tissue macrophages control their condition and guarantee
Externí odkaz:
https://doaj.org/article/39425946ca2f487187600bad5c676da2
Publikováno v:
Bulletin of Experimental Biology and Medicine. 174:779-783
Autor:
Olga V. Kovaleva, Polina A. Podlesnaya, Viktor L. Chang, Nikolai A. Ognerubov, Alexei N. Gratchev, N. A. Kozlov, Ivan S. Stilidi, Nikolai E. Kushlinskii
Publikováno v:
Acta Naturae. 14:75-83
A comprehensive analysis of the cell phenotype of the inflammatory infiltrate of the tumor stroma represents a promising area of molecular oncology. The study of not only soluble forms of various immunoregulatory molecules, but also their membrane-bo