Zobrazeno 1 - 10
of 20
pro vyhledávání: '"A N, Chuvilin"'
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166911 (2016)
A common problem of the preparation of hexachlorofluorescein labeled oligonucleotides is the transformation of the fluorophore to an arylacridine derivative under standard ammonolysis conditions. We show here that the arylacridine byproduct with dist
Externí odkaz:
https://doaj.org/article/2c32ae516ffd44aabbef85724103d6b8
Publikováno v:
Тонкие химические технологии, Vol 7, Iss 4, Pp 72-74 (2012)
A new way of deblocking of synthetic hexachlorofluorescein-oligodeoxyribonucleotides (HEX-ODN) prevents the modification of the label and the accumulation of difficult to separated by-product. It was shown that this method increases the efficiency of
Externí odkaz:
https://doaj.org/article/bc6e658f2afb4a508e4faf4c5933a269
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 11, p e0166911 (2016)
PLoS ONE, Vol 11, Iss 11, p e0166911 (2016)
A common problem of the preparation of hexachlorofluorescein labeled oligonucleotides is the transformation of the fluorophore to an arylacridine derivative under standard ammonolysis conditions. We show here that the arylacridine byproduct with dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12753e27db5338464fa2874ddae1f89
https://pubmed.ncbi.nlm.nih.gov/27861573
https://pubmed.ncbi.nlm.nih.gov/27861573
Autor:
M. A. Zaitseva, I. P. Smirnov, Olga N. Tatarinova, Galina E. Pozmogova, A. N. Chuvilin, V. M. Govorun
Publikováno v:
Nanotechnologies in Russia. 3:391-396
In this paper, we demonstrate that nickel nanoparticles are suitable and promising for forming multifunctional biopolymer structures and have advantages over other nanoplatforms. We found that aggregates of nickel nanoparticles form stable associates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ca4006e4542b82c29e06e1af1039044
https://doi.org/10.1134/s1995078008050157
https://doi.org/10.1134/s1995078008050157
Publikováno v:
Molecular Biology. 42:253-260
Recombinant protein PGEk, consisting of the human epidermal growth factor (hEGF) and a DNA-binding domain, proved to be capable of interacting with the hEGF receptor and inducing cell proliferation, as characteristic of hEGF. PGEk complexes with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28ac45dff6522213416413364cbb97ef
https://doi.org/10.1134/s0026893308020118
https://doi.org/10.1134/s0026893308020118
Autor:
Anna K. Shchyolkina, I. A. Besschetnova, Galina E. Pozmogova, Olga F. Borisova, A. N. Chuvilin
Publikováno v:
Molecular Biology. 40:433-439
A study was made of the complexation of the protein vector PGEk, which transfers nucleic acids into the nuclei of cancer cells, with phosphodiester d(TTAGGG)4 (TMO) and phosphorothioate Sd(TTAGGG)4 (TMS) oligonucleotides, which inhibit telomerase. PG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f64c3eedbe37ccb0a5b6edee4f414377
https://doi.org/10.1134/s0026893306030101
https://doi.org/10.1134/s0026893306030101
Autor:
Nikolay A. Barinov, Edward N. Timofeev, Igor P. Smirnov, Dmitry V. Klinov, Olga N. Tatarinova, Dmitry N. Kaluzhny, Anna M. Varizhuk, Vladimir B. Tsvetkov, A. N. Chuvilin, Galina E. Pozmogova, Dmitry Basmanov
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89383 (2014)
PLoS ONE
PLoS ONE
Noncanonically structured DNA aptamers to thrombin were examined. Two different approaches were used to improve stability, binding affinity and biological activity of a known thrombin-binding aptamer. These approaches are chemical modification and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ebaf1eda74764b736763a281cfe0d3
http://europepmc.org/articles/PMC3930721?pdf=render
http://europepmc.org/articles/PMC3930721?pdf=render
Autor:
Gleb Y. Fisunov, Alexandr O. Chizhov, Roman A. Novikov, Anna M. Varizhuk, Dmitry N. Kaluzhny, Galina E. Pozmogova, A. N. Chuvilin, V. L. Florentiev, Igor P. Smirnov, Olga N. Tatarinova
Publikováno v:
The Journal of organic chemistry. 78(12)
New oligonucleotide analogues with triazole internucleotide linkages were synthesized, and their hybridization properties were studied. The analogues demonstrated DNA binding affinities similar to those of unmodified oligonucleotides. The modificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9d1d823da771d04e567d996a403f30
https://pubmed.ncbi.nlm.nih.gov/23724994
https://pubmed.ncbi.nlm.nih.gov/23724994
Publikováno v:
Bioconjugate chemistry. 20(8)
HEX-labeled oligonucleotides obtained via typical synthetic protocols may contain more than 15% of material with altered spectral characteristics. We discovered hexachlorofluorescein residue transformation unknown earlier for standard DNA ammonolysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd099159ff67d4e5b5af010e79a83a3d
https://pubmed.ncbi.nlm.nih.gov/19601641
https://pubmed.ncbi.nlm.nih.gov/19601641
Publikováno v:
Molekuliarnaia biologiia. 42(2)
The recombinant protein PGEk, containing residual of the human epidermal factor (hEGF) bearing DNA binding sequence, retains ability of hEGF to bind with hEGF receptor and to induce cell proliferation was shown. On an example of PGEk complexes with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1fc459b61f5ba0c3b32ef503ddd3a17f
https://pubmed.ncbi.nlm.nih.gov/18610837
https://pubmed.ncbi.nlm.nih.gov/18610837