Zobrazeno 1 - 10
of 58
pro vyhledávání: '"A N, Chepkova"'
Publikováno v:
Neural Plasticity, Vol 2015 (2015)
Age-related alterations in the expression of genes and corticostriatal synaptic plasticity were studied in the dorsal striatum of mice of four age groups from young (2-3 months old) to old (18–24 months of age) animals. A significant decrease in tr
Externí odkaz:
https://doaj.org/article/358dfcf0cb584afabc8fb46e97aed7c5
Publikováno v:
Neurobiology of Disease, Vol 23, Iss 3, Pp 512-521 (2006)
Hyperammonemia, a major pathophysiological factor in hepatic encephalopathy, impairs long-term potentiation (LTP) of synaptic transmission, a cellular model of learning and memory, in the hippocampus. We have now studied the protective action of taur
Externí odkaz:
https://doaj.org/article/09592f400f1c4a8aad1815a2560c5080
Autor:
Filipe Rodrigues Almeida, Hans-Jürgen Bidmon, Olga A. Sergeeva, Helmut L. Haas, Dieter Häussinger, A. N. Chepkova, Boris Görg
Publikováno v:
CNS Neuroscience & Therapeutics
Aims Histamine H3 receptor (H3R) antagonists/inverse agonists increase vigilance. We studied brain histaminergic pathways under hyperammonemia and the transcriptome of receptors and their signaling cascades to provide a rationale for wake‐promoting
Autor:
Roberto De Luca, Andreas Bauer, Helmut L. Haas, Aissa N. Chepkova, Karolina Mazur, Olga A. Sergeeva
Publikováno v:
Neuropharmacology. 119
N-oleoyl-dopamine (OLDA) is an amide of dopamine and oleic acid, synthesized in catecholaminergic neurons. The present study investigates OLDA targets in midbrain dopaminergic (DA) neurons. Substantia Nigra compacta (SNc) DA neurons recorded in brain
Publikováno v:
Archives of Biochemistry and Biophysics. 536:176-182
Hyperammonemia is a major pathophysiological factor in encephalopathies associated with acute and chronic liver failure. On mouse brain slice preparations we analyzed the effects of ammonium on the characteristics of corticostriatal long-term potenti
Publikováno v:
Journal of Neurochemistry. 122:545-556
Hyperammonemia is a major pathophysiological factor in encephalopathies associated with acute and chronic liver failure. On mouse brain slice preparations, we analyzed the effects of ammonia on the characteristics of corticostriatal long-term depress
Autor:
Olga A. Sergeeva, Helmut L. Haas, A. N. Chepkova, Evgenij Yanovsky, Hiroshi Ohtsu, Jian-Sheng Lin, Régis Parmentier
Publikováno v:
Cellular and Molecular Neurobiology. 32:17-25
Genetic ablation of the histamine producing enzyme histidine decarboxylase (HDC) leads to alteration in exploratory behaviour and hippocampus-dependent learning. We investigated how brain histamine deficiency in HDC knockout mice (HDC KO) affects hip
Autor:
N. Doreulee, Wiebke Fleischer, A. N. Chepkova, Thomas Kazmierczak, Helmut L. Haas, Olga A. Sergeeva
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 459:131-141
In animal models of early Parkinson's disease (PD), motor deficits are accompanied by excessive striatal glutamate release. Blockade of group I metabotropic glutamate receptors (mGluRs), endocannabinoid degradation and nitric oxide (NO) synthesis com
Publikováno v:
Neuropharmacology. 55:139-147
Effects of the gap junction blocker carbenoxolone (CBX) on tetanus- and taurine-induced long-term potentiation (LTP) were studied on Schaffer collateral-CA1 field excitatory postsynaptic potentials (fEPSPs) in mouse hippocampal slices. Preincubation
Autor:
Helmut L. Haas, U. Warskulat, Olga A. Sergeeva, Mario Siebler, Wiebke Fleischer, D. Häussinger, A. N. Chepkova
Publikováno v:
The Journal of Physiology. 585:539-548
The Striatum is involved in the regulation of movements and motor skills. We have shown previously, that the osmolyte and neuromodulator taurine plays a role in striatal plasticity. We demonstrate now that hereditary taurine deficiency in taurine-tra