Mortality impact of low CAC density predominantly occurs in early atherosclerosis: explainable ML in the CAC consortium

Autor: Fay Y. Lin, Benjamin P. Goebel, Benjamin C. Lee, Yao Lu, Lohendran Baskaran, Yeonyee E. Yoon, Gabriel Thomas Maliakal, Umberto Gianni, A. Maxim Bax, Partho P. Sengupta, Piotr J. Slomka, Damini S. Dey, Alan Rozanski, Donghee Han, Daniel S. Berman, Matthew J. Budoff, Michael D. Miedema, Khurram Nasir, John Rumberger, Seamus P. Whelton, Michael J. Blaha, Leslee J. Shaw

Publikováno v: Journal of Cardiovascular Computed Tomography. 17:28-33

Machine learning (ML) models of risk prediction with coronary artery calcium (CAC) and CAC characteristics exhibit high performance, but are not inherently interpretable.To determine the direction and magnitude of impact of CAC characteristics on 10-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49873b3a1853dda89cb0bb698d314ff1
https://doi.org/10.1016/j.jcct.2022.10.001

Relationship Between Coronary Artery Calcium and Atherosclerosis Progression Among Patients With Suspected Coronary Artery Disease

Autor: Emma J. Hollenberg, Fay Lin, Michael J. Blaha, Matthew J. Budoff, Inge J. van den Hoogen, Umberto Gianni, Yao Lu, A. Maxim Bax, Alexander R. van Rosendael, Sara W. Tantawy, Daniele Andreini, Filippo Cademartiri, Kavitha Chinnaiyan, Jung Hyun Choi, Edoardo Conte, Pedro de Araújo Gonçalves, Martin Hadamitzky, Erica Maffei, Gianluca Pontone, Sanghoon Shin, Yong-Jin Kim, Byoung Kwon Lee, Eun Ju Chun, Ji Min Sung, Alessia Gimelli, Sang-Eun Lee, Jeroen J. Bax, Daniel S. Berman, Stephanie L. Sellers, Jonathon A. Leipsic, Ron Blankstein, Jagat Narula, Hyuk-Jae Chang, Leslee J. Shaw

Publikováno v: JACC: Cardiovascular Imaging, 15(6), 1063-1074. ELSEVIER SCIENCE INC

BACKGROUND Among symptomatic patients, it remains unclear whether a coronary artery calcium (CAC) score alone is sufficient or misses a sizeable burden and progressive risk associated with obstructive and nonobstructive atherosclerotic plaque.OBJECTI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dcac35ddf4afebdb7c08bb3e077bc4f
https://doi.org/10.1016/j.jcmg.2021.12.015

Associations between dyspnoea, coronary atherosclerosis, and cardiovascular outcomes

Autor: Jeroen J. Bax, Daniele Andreini, Jessica M. Peña, Joerg Hausleiter, Fay Y. Lin, Daniel S. Berman, Augustin Delago, Mouaz H. Al-Mallah, Jonathon Leipsic, Stephan Achenbach, Jagat Narula, Ronen Rubinshtein, Gudrun Feuchtner, Pedro de Araújo Gonçalves, Yong Jin Kim, Todd C. Villines, Erica Maffei, Gianluca Pontone, Martin Hadamitzky, Yao Lu, Ricardo C. Cury, Matthew J. Budoff, Kavitha Chinnaiyan, Heidi Gransar, Philipp A. Kaufmann, Alexander R. van Rosendael, Gilbert L. Raff, Jeff M. Smit, Subhi J. Al'Aref, A. Maxim Bax, Filippo Cademartiri, Inge J. van den Hoogen, James K. Min, Leslee J. Shaw, Benjamin J.W. Chow, Tracy Q. Callister, Hyuk Jae Chang, Hugo Marques

Publikováno v: Eur Heart J Cardiovasc Imaging
European Heart Journal-Cardiovascular Imaging, 23(2), 266-274. OXFORD UNIV PRESS
European heart journal. Cardiovascular Imaging, vol 23, iss 2

Aims The relationship between dyspnoea, coronary artery disease (CAD), and major cardiovascular events (MACE) is poorly understood. This study evaluated (i) the association of dyspnoea with the severity of anatomical CAD by coronary computed tomograp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555f0026ac752dd6cd7cd6f008264f19
https://hdl.handle.net/1887/3567752

Vessel-specific plaque features on coronary computed tomography angiography among patients of varying atherosclerotic cardiovascular disease risk

Autor: A Maxim, Bax, Yeonyee E, Yoon, Umberto, Gianni, Alexander R, van Rosendael, Yao, Lu, Xiaoyue, Ma, Benjamin P, Goebel, Sara W, Tantawy, Daniele, Andreini, Matthew J, Budoff, Filippo, Cademartiri, Kavitha, Chinnaiyan, Jung Hyun, Choi, Edoardo, Conte, Pedro, de Araújo Gonçalves, Ilan, Gottlieb, Martin, Hadamitzky, Jonathon A, Leipsic, Erica, Maffei, Gianluca, Pontone, Sanghoon, Shin, Yong Jin, Kim, Byoung Kwon, Lee, Eun Ju, Chun, Ji Min, Sung, Sang Eun, Lee, Daniel S, Berman, Jagat, Narula, Fay Y, Lin, Hyuk Jae, Chang, Leslee J, Shaw

Publikováno v: European heart journal. Cardiovascular Imaging. 23(9)

Aims The relationship between AtheroSclerotic CardioVascular Disease (ASCVD) risk and vessel-specific plaque evaluation using coronary computed tomography angiography (CCTA), focusing on plaque extent and composition, has not been examined. To evalua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::757fa99eb929253dfafc288b27fdc21a
https://pubmed.ncbi.nlm.nih.gov/35325083

Clinical risk factors and atherosclerotic plaque extent to define risk for major events in patients without obstructive coronary artery disease: the long-term coronary computed tomography angiography CONFIRM registry

Autor: Erica Maffei, James K. Min, Leslee J. Shaw, Gianluca Pontone, Kavitha Chinnaiyan, Subhi J. Al'Aref, A. Maxim Bax, Filippo Cademartiri, Jeroen J. Bax, Joerg Hausleiter, Fay Y. Lin, Ronen Rubinshtein, Inge J. van den Hoogen, Daniele Andreini, Yao Lu, Stephan Achenbach, Daniel S. Berman, Pedro de Araújo Gonçalves, Jessica M. Peña, Mouaz H. Al-Mallah, Gilbert L. Raff, Jeff M. Smit, Jonathon Leipsic, Martin Hadamitzky, Ricardo C. Cury, Augustin Delago, Philipp A. Kaufmann, Alexander R. van Rosendael, Gudrun Feuchtner, Yong Jin Kim, Matthew J. Budoff, Heidi Gransar, Benjamin J.W. Chow, Tracy Q. Callister, Hyuk Jae Chang, Todd C. Villines, Xiaoyue Ma, Hugo Marques

Publikováno v: European heart journal. Cardiovascular Imaging, vol 21, iss 5
European Heart Journal-Cardiovascular Imaging, 21(5), 479-488. OXFORD UNIV PRESS

Aims In patients without obstructive coronary artery disease (CAD), we examined the prognostic value of risk factors and atherosclerotic extent. Methods and results Patients from the long-term CONFIRM registry without prior CAD and without obstructiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a486585336b9bcd63c921a20a8af60
https://escholarship.org/uc/item/5hw3d6xt