Zobrazeno 1 - 10
of 98
pro vyhledávání: '"A Mangravita-Novo"'
Autor:
Aftab A. Khan, Ashraf El-Sayed, Asma Akbar, Arianna Mangravita-Novo, Shaheen Bibi, Zunaira Afzal, David J. Norman, Gul Shad Ali
Publikováno v:
Plant Methods, Vol 13, Iss 1, Pp 1-13 (2017)
Abstract Background Most current methods for constructing guide RNAs (gRNA) for the CRISPR/Cas9 genome editing system, depend on traditional cloning using specific type IIS restriction enzymes and DNA ligation. These methods consist of multiple steps
Externí odkaz:
https://doaj.org/article/fca60df2c67b4713b30c80c95f943ed9
Autor:
Preuss, Janina, Hedrick, Michael, Sergienko, Eduard, Pinkerton, Anthony, Mangravita-Novo, Arianna, Smith, Layton, Marx, Carolin, Fischer, Elisabeth, Jortzik, Esther, Rahlfs, Stefan, Becker, Katja *, Bode, Lars
Publikováno v:
In SLAS Discovery July 2012 17(6):738-751
Publikováno v:
Plant disease. 90(6)
Various bactericides were screened for efficacy in protecting geranium plants (Pelargonium hortorum) from Ralstonia solanacearum infection. Many of these bactericides were found to slow the disease progress; however, they were not able to protect the
Autor:
Patrick R. Maloney, Chi K. Leung, Satyamaheshwar Peddibhotla, Hendrik Luesch, Arianna Mangravita-Novo, Anthony B. Pinkerton, Siobhan Malany, Michelle S. Bousquet, Keith P. Choe, Paul Hershberger, Ying Wang, Layton H. Smith, Pauline Fontaine
Publikováno v:
ACS Chemical Biology. 10:1871-1879
Nematodes parasitize ∼1/3 of humans worldwide, and effective treatment via administration of anthelmintics is threatened by growing resistance to current therapies. The nematode transcription factor SKN-1 is essential for development of embryos and
Publikováno v:
Acta Horticulturae. :33-37
Autor:
David J. Norman, Shaheen Bibi, Aftab A. Khan, Ashraf S.A. El-Sayed, Arianna Mangravita-Novo, Zunaira Afzal, Gul Shad Ali, Asma Akbar
Publikováno v:
Plant Methods
Plant Methods, Vol 13, Iss 1, Pp 1-13 (2017)
Plant Methods, Vol 13, Iss 1, Pp 1-13 (2017)
Background Most current methods for constructing guide RNAs (gRNA) for the CRISPR/Cas9 genome editing system, depend on traditional cloning using specific type IIS restriction enzymes and DNA ligation. These methods consist of multiple steps of cloni
Autor:
Khan, Aftab, El-Sayed, Ashraf, Akbar, Asma, Mangravita-Novo, Arianna, Bibi, Shaheen, Zunaira Afzal, Norman, David, Ali, Gul
Additional file 1. This file contains two Figures as follows. Figure S1. Schematics illustrating sequences and positions of primers relative to the final CRISPR RNA. Figure S2. Restriction fragment length polymorphism (RFLP) analysis of YFP CRISPR RN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df94eb877e7fb7e3dadb06626e6a734
Autor:
Becky Hood, Larry S. Barak, Glen R. Hanson, Patrick R. Maloney, Kevin Nguyen, Stefan Vasile, Sumeet Salaniwal, Marc G. Caron, Yujie Li, Satyamaheshwar Peddibhotla, Derek Stonich, Alka Mehta, Anthony B. Pinkerton, Susanne Heynen-Genel, Thomas D.Y. Chung, Eigo Suyama, Wilson Gray, Palak Gosalia, Michael Vicchiarelli, Arianna Mangravita-Novo, Gregory P. Roth, Paul Hershberger, Layton H. Smith, Monika Milewski, Michael P Hedrick, Ying Su, Eliot Sugarman, James B. Thomas
Publikováno v:
ACS Medicinal Chemistry Letters. 4:846-851
The neurotensin 1 receptor (NTR1) is an important therapeutic target for a range of disease states including addiction. A high-throughput screening campaign, followed by medicinal chemistry optimization, led to the discovery of a nonpeptidic β-arres
Autor:
Anthony B. Pinkerton, Gregory P. Roth, Eigo Suyama, Layton H. Smith, Becky Hood, Danielle McAnally, Esther Jortzik, Thomas D.Y. Chung, Palak Gosalia, Michael Vicchiarelli, Arianna Mangravita-Novo, Satyamaheshwar Peddibhotla, Jena Diwan, Stefan Rahlfs, Eduard Sergienko, Paul Hershberger, Kevin Nguyen, Stefan Vasile, Katja Becker, Patrick R. Maloney, Monika Milewski, Yujie Linda Li, Michael P Hedrick, Eliot Sugarman, Janina Preuss, Lars Bode
Publikováno v:
Journal of Medicinal Chemistry. 55:7262-7272
A high-throughput screen of the NIH’s MLSMR collection of ∼340000 compounds was undertaken to identify compounds that inhibit Plasmodium falciparum glucose-6-phosphate dehydrogenase (PfG6PD). PfG6PD is important for proliferating and propagating
Autor:
Esther Jortzik, Arianna Mangravita-Novo, Katja Becker, Eduard Sergienko, Elisabeth Fischer, Anthony B. Pinkerton, Carolin Marx, Stefan Rahlfs, Michael P Hedrick, Janina Preuss, Lars Bode, Layton H. Smith
Publikováno v:
J Biomol Screen
Plasmodium falciparum causes severe malaria infections in millions of people every year. The parasite is developing resistance to the most common antimalarial drugs, which creates an urgent need for new therapeutics. A promising and attractive target