Zobrazeno 1 - 10
of 102
pro vyhledávání: '"A M Spagnoli"'
Autor:
T. Pereira, L. Arbaret, J. Andújar, M. Laumonier, M. Spagnoli, C. Gumiaux, G. Laurent, A. Slodczyk, I. Di Carlo
Publikováno v:
European Journal of Mineralogy, Vol 36, Pp 491-524 (2024)
In the last decades the mush model has been generalized to the complete trans-crustal magmatic system in which differentiation would be driven by segregation and extraction of trapped melts from crystal-rich mushes. Melt extraction processes involved
Externí odkaz:
https://doaj.org/article/dbebdd57745a4ee5af40b566399f3045
Autor:
Laura M. Mueller, Abigail Isaacson, Heather Wilson, Anna Salowka, Isabel Tay, Maolian Gong, Nancy Samir Elbarbary, Klemens Raile, Francesca M. Spagnoli
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Missense variants are the most common type of coding genetic variants. Their functional assessment is fundamental for defining any implication in human diseases and may also uncover genes that are essential for human organ development. Here,
Externí odkaz:
https://doaj.org/article/d4dcf83d6ce84bcbaf966a9c073f3f02
Autor:
Manon Moulis, Steve Vincent Maurice Runser, Laura Glorieux, Nicolas Dauguet, Christophe Vanderaa, Laurent Gatto, Donatienne Tyteca, Patrick Henriet, Francesca M. Spagnoli, Dagmar Iber, Christophe E. Pierreux
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Development of the pancreas is driven by an intrinsic program coordinated with signals from other cell types in the epithelial environment. These intercellular communications have been so far challenging to study because of the low concentra
Externí odkaz:
https://doaj.org/article/3635ecf0825b4dbab51e89b71438d34e
Autor:
Caoimhe Goldrick, Ina Guri, Gabriel Herrera-Oropeza, Charlotte O’Brien-Gore, Errin Roy, Maja Wojtynska, Francesca M. Spagnoli
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Cell-cell interactions underlay organ formation and function during homeostasis. Changes in communication between cells and their surrounding microenvironment are a feature of numerous human diseases, including metabolic disease and neurological diso
Externí odkaz:
https://doaj.org/article/55a532f8e2904fabb9662a9493dd33b2
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
A role for Slit/Robo signalling in pancreas development has not been defined. Here, the authors generate Robo1/Robo2 knockout mice to identify both as needed for establishing initial pancreatic cell identity as well as for proliferation and survival
Externí odkaz:
https://doaj.org/article/3333c45137184a129f28864d1c262e72
Publikováno v:
Molecular Metabolism, Vol 8, Iss , Pp 96-105 (2018)
Objective: Actin cytoskeleton remodeling is necessary for glucose-stimulated insulin secretion in pancreatic β-cells. A mechanistic understanding of actin dynamics in the islet is paramount to a better comprehension of β-cell dysfunction in diabete
Externí odkaz:
https://doaj.org/article/719eab4614cd42cf889190c03e5d132c
Autor:
Pierreux, Laura Glorieux, Laura Vandooren, Sylvie Derclaye, Sébastien Pyr dit Ruys, Paloma Oncina-Gil, Anna Salowka, Gaëtan Herinckx, Elias Aajja, Pascale Lemoine, Catherine Spourquet, Hélène Lefort, Patrick Henriet, Donatienne Tyteca, Francesca M. Spagnoli, David Alsteens, Didier Vertommen, Christophe E.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 10268
The pancreas is a complex organ consisting of differentiated cells and extracellular matrix (ECM) organized adequately to enable its endocrine and exocrine functions. Although much is known about the intrinsic factors that control pancreas developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::3f486532914d3d45c4e11b2ccccf4d1f
Autor:
Nuria Cerdá-Esteban, Heike Naumann, Silvia Ruzittu, Nancy Mah, Igor M. Pongrac, Corinna Cozzitorto, Angela Hommel, Miguel A. Andrade-Navarro, Ezio Bonifacio, Francesca M. Spagnoli
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Liver and pancreas cells arise from a common endoderm progenitor in the embryo, but what regulates their cell fate is unclear. Here, the authors show that expression of the Three-Amino-acid-Loop-Extension (TALE) homeobox TG-interacting factor 2 (TGIF
Externí odkaz:
https://doaj.org/article/7ebdf3d8a92040efa4c2ffd160f951bf
Publikováno v:
Journal of Plastic, Reconstructive & Aesthetic Surgery. 75:970-979
Background Complex Regional Pain Syndrome (CRPS) is a neuropathic pain condition with no universally recognised treatment. The study evaluates the efficacy of a therapeutic protocol consisting of oral citalopram and lidocaine injections in patients a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393715aa9714af7a8337d52ef4d8f559
https://doi.org/10.1016/j.bjps.2021.11.022
https://doi.org/10.1016/j.bjps.2021.11.022
SUMMARYDuring organ formation, progenitor cells need to acquire the diversity of cell identities found in the organ as well as organize themselves into distinct structural units. How these processes are coordinated, and how tissue architecture(s) are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64e494b78450569e64994ab026a63f86
https://doi.org/10.1101/2023.01.26.525717
https://doi.org/10.1101/2023.01.26.525717
