Zobrazeno 1 - 10
of 28
pro vyhledávání: '"A M Kissonerghis"'
Autor:
Marc Feldmann, Martin R Turner, A M Kissonerghis, G Buchan, C Haworth, A Ziegler, Ravinder N. Maini, K Barrett, Fionula M. Brennan, David Chantry
Publikováno v:
Scopus-Elsevier
HLA class II expression is notable in rheumatoid arthritis. We have investigated the mechanism of HLA class II regulation in the joints and found local synthesis, as judged by mRNA levels to be high. The role of antigen presentation in maintaining cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b96e24e167dc9446908d59e4d764092
https://doi.org/10.3109/03009748809102951
https://doi.org/10.3109/03009748809102951
Autor:
Andrew P. Cope, A M Kissonerghis, K Barrett, Marc Feldmann, P W Gray, Brian M. J. Foxwell, David A. Taylor-Fishwick
Publikováno v:
Scopus-Elsevier
Tumor necrosis factor (TNF) mediates its pleiotropic effects via high-affinity cell surface receptors. In man, molecular cloning has identified two distinct, independent TNF receptors (TNFR) of 55 and 75 kDa. It is unclear, however, whether the multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f5190c20a19073ab08584f999729976
https://ora.ox.ac.uk/objects/uuid:aee57b19-39f1-423c-b866-143aed4ce36a
https://ora.ox.ac.uk/objects/uuid:aee57b19-39f1-423c-b866-143aed4ce36a
Autor:
A. M. Kissonerghis, M. Ritter, Gary Tanigawa, K. M. Price, Mary Collins, Susumu Tonegawa, Michael John Owen
Publikováno v:
Proceedings of the National Academy of Sciences. 82:4503-4507
A cDNA clone encoding the alpha chain of the human T-cell antigen receptor was isolated by screening a library from the human T-cell line Jurkat with a mouse alpha-chain cDNA clone. This human alpha-chain clone, together with a human antigen receptor
Publikováno v:
Journal of Biological Chemistry. 255:9678-9684
The biosynthesis of the HLA-A and -B antigens was studied in the B lymphoblastoid cell line BRI 8 and the Burkitt lymphoma line DAudi. The heavy chains of the HLA-A and -B antigens were inserted asymmetrically into the rough endoplasmic reticulum of
Publikováno v:
The EMBO Journal. 4:1211-1215
A number of cDNA clones homologous to the human T-cell receptor beta-chain gene have been isolated from a library constructed from the human leukaemic cell line Jurkat. The nucleotide sequences of two of these clones demonstrate that Jurkat synthesiz
Publikováno v:
Autoimmunity. 4:255-266
In both thyroid autoimmune diseases Graves' and Hashimoto's thyroiditis, the epithelial thyroid follicular cells (TFC) have been shown to express HLA class II molecules, and can restimulate autoreactive T cells cloned from the diseased tissue. This a
Autor:
Marc Feldmann, P De Berardinis, M Kissonerghis, B Grubeck-Loebenstein, Marco Londei, Adrienne Verhoef
Publikováno v:
Proceedings of the National Academy of Sciences. 86:8502-8506
Whereas most T cells express surface CD4 or CD8 molecules, a minority lacks both. CD4-8- cells usually express the gamma delta T-cell receptor, but here we describe a population of CD4-8- T cells from the peripheral blood that express the alpha beta
Publikováno v:
Journal of Biological Chemistry. 256:8987-8993
The biosynthesis of the HLA-DR antigens was studied in the B lymphoblastoid cell line BRI 8. Three chains, of molecular weights 33,000 (alpha), 31,000 (p31), and 26,000 (beta) were detected intracellularly in pulse-labeled cells by immunoprecipitatio
Autor:
K Pirich, G Buchan, M Kissonerghis, B Grubeck-Loebenstein, Martin R Turner, R Roka, B Niederle, H Kassal, R Sadeghi, Marco Londei
Publikováno v:
Journal of Clinical Investigation. 83:764-770
The production and growth regulatory activity of transforming growth factor beta were studied in human thyroid tissue. As estimated by its mRNA expression in fresh tissue samples, transforming growth factor beta was produced in normal and in diseased
The biosynthesis of the HLA-A and -B antigens has been studied in human B lymphoblastoid cell lines. The heavy chain is inserted asymmetrically into the rough endoplasmic reticulum. Association of the heavy chain with β 2 -microglobulin occurs durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c28ffc6226351c88d4928e2b087df01
https://doi.org/10.1016/b978-0-08-027988-6.50053-7
https://doi.org/10.1016/b978-0-08-027988-6.50053-7