Role of small airway dysfunction in unexplained exertional dyspnoea

Autor: Alexis L. Sharpe, Joan Reibman, Beno W. Oppenheimer, Roberta M. Goldring, Mengling Liu, Yongzhao Shao, Isaac Bohart, Benjamin Kwok, Tatiana Weinstein, Doreen Addrizzo-Harris, Daniel H. Sterman, Kenneth I. Berger

Publikováno v: ERJ Open Research, Vol 9, Iss 3 (2023)

Background Isolated small airway abnormalities may be demonstrable at rest in patients with normal spirometry; however, the relationship of these abnormalities to exertional symptoms remains uncertain. This study uses an augmented cardiopulmonary exe

Externí odkaz: https://doaj.org/article/090bb09f13084a8494a53bbdf276cdf1

Respiratory impedance measured using impulse oscillometry in a healthy urban population

Autor: Kenneth I. Berger, Margaret Wohlleber, Roberta M. Goldring, Joan Reibman, Mark R. Farfel, Stephen M. Friedman, Beno W. Oppenheimer, Steven D. Stellman, James E. Cone, Yongzhao Shao

Publikováno v: ERJ Open Research, Vol 7, Iss 1 (2021)

This study derives normative prediction equations for respiratory impedance in a healthy asymptomatic urban population using an impulse oscillation system (IOS). In addition, this study uses body mass index (BMI) in the equations to describe the effe

Externí odkaz: https://doaj.org/article/5d9bdd9429f941e9999e371bc6732809

Computer clinical decision support that automates personalized clinical care: a challenging but needed healthcare delivery strategy

Autor: Alan H Morris, Christopher Horvat, Brian Stagg, David W Grainger, Michael Lanspa, James Orme, Terry P Clemmer, Lindell K Weaver, Frank O Thomas, Colin K Grissom, Ellie Hirshberg, Thomas D East, Carrie Jane Wallace, Michael P Young, Dean F Sittig, Mary Suchyta, James E Pearl, Antinio Pesenti, Michela Bombino, Eduardo Beck, Katherine A Sward, Charlene Weir, Shobha Phansalkar, Gordon R Bernard, B Taylor Thompson, Roy Brower, Jonathon Truwit, Jay Steingrub, R Duncan Hiten, Douglas F Willson, Jerry J Zimmerman, Vinay Nadkarni, Adrienne G Randolph, Martha A Q Curley, Christopher J L Newth, Jacques Lacroix, Michael S D Agus, Kang Hoe Lee, Bennett P deBoisblanc, Frederick Alan Moore, R Scott Evans, Dean K Sorenson, Anthony Wong, Michael V Boland, Willard H Dere, Alan Crandall, Julio Facelli, Stanley M Huff, Peter J Haug, Ulrike Pielmeier, Stephen E Rees, Dan S Karbing, Steen Andreassen, Eddy Fan, Roberta M Goldring, Kenneth I Berger, Beno W Oppenheimer, E Wesley Ely, Brian W Pickering, David A Schoenfeld, Irena Tocino, Russell S Gonnering, Peter J Pronovost, Lucy A Savitz, Didier Dreyfuss, Arthur S Slutsky, James D Crapo, Michael R Pinsky, Brent James, Donald M Berwick

Publikováno v: Morris, A H, Horvat, C, Stagg, B, Grainger, D W, Lanspa, M, Orme, J, Clemmer, T P, Weaver, L K, Thomas, F O, Grissom, C K, Hirshberg, E, East, T D, Wallace, C J, Young, M P, Sittig, D F, Suchyta, M, Pearl, J E, Pesenti, A, Bombino, M, Beck, E, Sward, K A, Weir, C, Phansalkar, S, Bernard, G R, Thompson, B T, Brower, R, Truwit, J, Steingrub, J, Hiten, R D, Willson, D F, Zimmerman, J J, Nadkarni, V, Randolph, A G, Curley, M A Q, Newth, C J L, Lacroix, J, Agus, M S D, Lee, K H, deBoisblanc, B P, Moore, F A, Evans, R S, Sorenson, D K, Wong, A, Boland, M V, Dere, W H, Crandall, A, Facelli, J, Huff, S M, Haug, P J, Pielmeier, U, Rees, S E, Karbing, D S, Andreassen, S, Fan, E, Goldring, R M, Berger, K I, Oppenheimer, B W, Ely, E W, Pickering, B W, Schoenfeld, D A, Tocino, I, Gonnering, R S, Pronovost, P J, Savitz, L A, Dreyfuss, D, Slutsky, A S, Crapo, J D, Pinsky, M R, James, B & Berwick, D M 2022, ' Computer clinical decision support that automates personalized clinical care : a challenging but needed healthcare delivery strategy ', Journal of the American Medical Informatics Association, vol. 30, no. 1, pp. 178-194 . https://doi.org/10.1093/jamia/ocac143

How to deliver best care in various clinical settings remains a vexing problem. All pertinent healthcare-related questions have not, cannot, and will not be addressable with costly time- and resource-consuming controlled clinical trials. At present,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b6c6925909e2d340b34ac7b62d586b
https://pubmed.ncbi.nlm.nih.gov/36125018

Pulmonary Vascular Congestion: A Mechanism for Distal Lung Unit Dysfunction in Obesity.

Autor: Beno W Oppenheimer, Kenneth I Berger, Saleem Ali, Leopoldo N Segal, Robert Donnino, Stuart Katz, Manish Parikh, Roberta M Goldring

Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0152769 (2016)

RATIONALE:Obesity is characterized by increased systemic and pulmonary blood volumes (pulmonary vascular congestion). Concomitant abnormal alveolar membrane diffusion suggests subclinical interstitial edema. In this setting, functional abnormalities

Externí odkaz: https://doaj.org/article/85b81d369a7f468d8acc9c03de3bb6bb

Enabling a learning healthcare system with automated computer protocols that produce replicable and personalized clinician actions

Autor: Jacques Lacroix, Roy G. Brower, Katherine A. Sward, Derek C. Angus, Jay S. Steingrub, Arthur S. Slutsky, Stanley M. Huff, Jonathon D. Truwit, Antonio Pesenti, Kenneth I. Berger, Ognjen Gajic, Adrienne G. Randolph, Beno W. Oppenheimer, E. Wesley Ely, Brent C. James, Bennett P. deBoisblanc, James F. Orme, Alan H. Morris, Thomas D. East, Steen Andreassen, Charlene R. Weir, Anthony Wong, Peter J. Pronovost, Michael V. Boland, Vinay M. Nadkarni, Lindell K. Weaver, Lucy Savitz, Dean F. Sittig, Julio C. Facelli, Alan S. Crandall, Colin K. Grissom, Ellie Hirshberg, David W. Grainger, R. Duncan Hite, Jerry J. Zimmerman, Michael S. D. Agus, Gordon R. Bernard, B. Taylor Thompson, Christopher J. L. Newth, Douglas F. Willson, Shobha Phansalkar, Didier Dreyfuss, Stephen Edward Rees, Willard H. Dere, Carrie Jane Wallace, Eduardo Beck, Roberta M. Goldring, R. Scott Evans, Brian C. Stagg, Martha A. Q. Curley, Dean K. Sorenson, Russell S. Gonnering, Brian W. Pickering, David A. Schoenfeld, Dan Stieper Karbing, Irena Tocino, Eddy Fan, Michael P. Young, Michela Bombino, Michael J. Lanspa, James D. Crapo, Michael R. Pinsky, Ulrike Pielmeier, Frank Thomas, Kang H. Lee, Terry P. Clemmer, Donald M. Berwick, Peter J. Haug

Publikováno v: Morris, A H, Stagg, B, Lanspa, M, Orme, J, Clemmer, T P, Weaver, L K, Thomas, F, Grissom, C K, Hirshberg, E, East, T D, Wallace, C J, Young, M P, Sittig, D F, Pesenti, A, Bombino, M, Beck, E, Sward, K A, Weir, C, Phansalkar, S S, Bernard, G R, Taylor Thompson, B, Brower, R, Truwit, J D, Steingrub, J, Duncan Hite, R, Willson, D F, Zimmerman, J J, Nadkarni, V M, Randolph, A, Curley, M A Q, Newth, C J L, Lacroix, J, Agus, M S D, Lee, K H, deBoisblanc, B P, Scott Evans, R, Sorenson, D K, Wong, A, Boland, M V, Grainger, D W, Dere, W H, Crandall, A S, Facelli, J C, Huff, S M, Haug, P J, Pielmeier, U, Rees, S E, Karbing, D S, Andreassen, S, Fan, E, Goldring, R, I Berger, K, W Oppenheimer, B, Ely, E W, Gajic, O, Pickering, B, A Schoenfeld, D, Tocino, I, S Gonnering, R, J Pronovost, P, A Savitz, L, Dreyfuss, D, S Slutsky, A, D Crapo, J, Angus, D, R Pinsky, M, James, B & Berwick, D 2021, ' Enabling a learning healthcare system with automated computer protocols that produce replicable and personalized clinician actions ', Journal of the American Medical Informatics Association, vol. 28, no. 6, pp. 1330-1344 . https://doi.org/10.1093/jamia/ocaa294
J Am Med Inform Assoc

Clinical decision-making is based on knowledge, expertise, and authority, with clinicians approving almost every intervention—the starting point for delivery of “All the right care, but only the right care,” an unachieved healthcare quality imp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6063b8fbca48a8de3665ab0cc6462033
https://vbn.aau.dk/da/publications/4df7c2e3-e678-4f2b-a3c9-cfc7a2de924f