Zobrazeno 1 - 10
of 366
pro vyhledávání: '"A M Forrester"'
Autor:
Telma Ventura, Antonella Fidanza, Marieangela C. Wilson, Daniel C. J. Ferguson, Phillip A. Lewis, Alisha May, Helen Taylor, Michael P. Rimmer, Christopher D. Gregory, Jan Frayne, Lesley M. Forrester
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Introduction: Erythroblastic island (EBI) macrophages play an essential role in the production and maturation of the vast numbers of red blood cells (RBCs) that are produced throughout life. Their location within the bone marrow makes it difficult to
Externí odkaz:
https://doaj.org/article/efb4c16f8d8e4e2885212d3119f67a99
Autor:
Alisha May, Telma Ventura, Antonella Fidanza, Helena Volmer, Helen Taylor, Nicola Romanò, Sunita L. D’Souza, James J. Bieker, Lesley M. Forrester
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Congenital dyserythropoietic anaemia (CDA) type IV has been associated with an amino acid substitution, Glu325Lys (E325K), in the transcription factor KLF1. These patients present with a range of symptoms, including the persistence of n
Externí odkaz:
https://doaj.org/article/c88b612d1db749ba874de06480b3d793
Publikováno v:
Frontiers in Marine Science, Vol 9 (2022)
Stony coral tissue loss disease has spread widely in the Caribbean and causes substantial changes to coral community composition because of its broad host range and high fatality rate. To reduce SCTLD impacts, intervention programs throughout the reg
Externí odkaz:
https://doaj.org/article/298907cae360469fa241e4ceaebfbda6
Autor:
Paolo Petazzi, Raul Torres-Ruiz, Antonella Fidanza, Heleia Roca-Ho, Francisco Gutierrez-Agüera, Julio Castaño, Sandra Rodriguez-Perales, Rafael Díaz de la Guardia, Belén López-Millán, Anna Bigas, Lesley M. Forrester, Clara Bueno, Pablo Menéndez
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 20, Iss , Pp 196-204 (2020)
Human pluripotent stem cells (hPSCs) and mesenchymal stromal/stem cells (hMSCs) are clinically relevant sources for cellular therapies and for modeling human development and disease. Many stem cell-based applications rely on the ability to activate s
Externí odkaz:
https://doaj.org/article/f77cc3d8fc8949cb8341a5d7065e2798
Publikováno v:
Atmospheric Chemistry and Physics, Vol 20, Pp 6055-6080 (2020)
Typical tropospheric temperatures render possible phase states of amorphous organic aerosol (OA) particles of solid, semisolid, and liquid. This will affect the multiphase oxidation kinetics involving the organic condensed-phase and gaseous oxidants
Externí odkaz:
https://doaj.org/article/247230a155a44aa492c95f8799bd20ef
Autor:
K. J. Evans, J. H. Kennedy, D. Lu, M. M. Forrester, S. Price, J. Fyke, A. R. Bennett, M. J. Hoffman, I. Tezaur, C. S. Zender, M. Vizcaíno
Publikováno v:
Geoscientific Model Development, Vol 12, Pp 1067-1086 (2019)
A collection of scientific analyses, metrics, and visualizations for robust validation of ice sheet models is presented using the Land Ice Verification and Validation toolkit (LIVVkit), version 2.1, and the LIVVkit Extensions repository (LEX), versio
Externí odkaz:
https://doaj.org/article/f7d809325cf54976a923b49c672ef44f
Autor:
Martha Lopez-Yrigoyen, Cheng-Tao Yang, Antonella Fidanza, Luca Cassetta, A. Helen Taylor, Angela McCahill, Erica Sellink, Marieke von Lindern, Emile van den Akker, Joanne C. Mountford, Jeffrey W. Pollard, Lesley M. Forrester
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
In vitro differentiation of red blood cells (RBCs) is a desirable therapy for various disorders. Here the authors develop a culture system using stem cell-derived macrophages to show that inducible expression of a transcription factor, KLF1, enhances
Externí odkaz:
https://doaj.org/article/b0cccdc9bb284487980ca46db3249dc4
Autor:
Antonella Fidanza, Martha Lopez-Yrigoyen, Nicola Romanò, Rhiannon Jones, A. Helen Taylor, Lesley M. Forrester
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract We have generated a drug-free, all-in-one dCAS9-SAM vector that can activate endogenous gene expression with the potential to modify cell fate. We demonstrate that this strategy can be used in a number of cell lines and avoids exceptionally
Externí odkaz:
https://doaj.org/article/edc72eebc6cf414da606a273513ae452
Autor:
Sharmin S. Haideri, Alison C. McKinnon, A. Helen Taylor, Phoebe Kirkwood, Philip J. Starkey Lewis, Eoghan O’Duibhir, Bertrand Vernay, Stuart Forbes, Lesley M. Forrester
Publikováno v:
npj Regenerative Medicine, Vol 2, Iss 1, Pp 1-11 (2017)
Stem cell-derived macrophages could treat liver fibrosis Macrophages, a type of white blood cell, when derived from embryonic stem cells in the laboratory reduce fibrosis in chronic liver disease. Lesley Forrester and colleagues from the University o
Externí odkaz:
https://doaj.org/article/aad90fc453e148b789e551de85f93a2f
Autor:
Nada Zaidan, Leslie Nitsche, Evangelia Diamanti, Rebecca Hannah, Antonella Fidanza, Nicola K. Wilson, Lesley M. Forrester, Berthold Göttgens, Katrin Ottersbach
Publikováno v:
Zaidan, N, Nitsche, L, Diamanti, E, Hannah, R, Fidanza, A, Wilson, N K, Forrester, L M, Gottgens, B & Ottersbach, K 2022, ' Endothelial-specific Gata3 expression is required for hematopoietic stem cell generation ', Stem Cell Reports . https://doi.org/10.1016/j.stemcr.2022.06.008
To generate sufficient numbers of transplantable hematopoietic stem cells (HSCs) in vitro, a detailed understanding of how this process takes place in vivo is essential. The endothelial-to-hematopoietic transition (EHT), which culminates in the produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa3588fa79fe12cb01d9501374a75a6
https://doi.org/10.1016/j.stemcr.2022.06.008
https://doi.org/10.1016/j.stemcr.2022.06.008