Zobrazeno 1 - 10
of 4 869
pro vyhledávání: '"A Mägi"'
Autor:
Ville Salo, Juhani Määttä, Eeva Sliz, FinnGen, Ene Reimann, Reedik Mägi, Estonian Biobank Research Team, Kadri Reis, Abdelrahman G. Elhanas, Anu Reigo, Priit Palta, Tõnu Esko, Jaro Karppinen, Johannes Kettunen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Given that lumbar disc herniation (LDH) is a prevalent spinal condition that causes significant individual suffering and societal costs, the genetic basis of LDH has received relatively little research. Our aim is to increase understanding o
Externí odkaz:
https://doaj.org/article/e11fbdff18b34dd8bca25fae232611aa
Autor:
Mary M. Barker, Kadri Kõiv, Ingibjörg Magnúsdóttir, Hannah Milbourn, Bin Wang, Xinkai Du, Gillian Murphy, Eva Herweijer, Elísabet U. Gísladóttir, Huiqi Li, Anikó Lovik, Anna K. Kähler, Archie Campbell, Maria Feychting, Arna Hauksdóttir, Emily E. Joyce, Edda Bjork Thordardottir, Emma M. Frans, Asle Hoffart, Reedik Mägi, Gunnar Tómasson, Kristjana Ásbjörnsdóttir, Jóhanna Jakobsdóttir, Ole A. Andreassen, Patrick F. Sullivan, Sverre Urnes Johnson, Thor Aspelund, Ragnhild Eek Brandlistuen, Helga Ask, Daniel L. McCartney, Omid V. Ebrahimi, Kelli Lehto, Unnur A. Valdimarsdóttir, Fredrik Nyberg, Fang Fang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Individuals with mental illness are at higher risk of severe COVID-19 outcomes. However, previous studies on the uptake of COVID-19 vaccination in this population have reported conflicting results. Using data from seven cohort studies (N = 3
Externí odkaz:
https://doaj.org/article/30508fc0e71b4bbeba07007ae76b359c
Autor:
Henrike O. Heyne, Fanny-Dhelia Pajuste, Julian Wanner, Jennifer I. Daniel Onwuchekwa, Reedik Mägi, Aarno Palotie, FinnGen, Estonian Biobank research team, Reetta Kälviainen, Mark J. Daly
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract A diagnosis of epilepsy has significant consequences for an individual but is often challenging in clinical practice. Novel biomarkers are thus greatly needed. Here, we investigated how common genetic factors (epilepsy polygenic risk scores,
Externí odkaz:
https://doaj.org/article/94371ca8bb284934af48236395a24f00
Autor:
Bradley Jermy, Kristi Läll, Brooke N. Wolford, Ying Wang, Kristina Zguro, Yipeng Cheng, Masahiro Kanai, Stavroula Kanoni, Zhiyu Yang, Tuomo Hartonen, Remo Monti, Julian Wanner, Omar Youssef, Estonian Biobank research team, FinnGen, Christoph Lippert, David van Heel, Yukinori Okada, Daniel L. McCartney, Caroline Hayward, Riccardo E. Marioni, Simone Furini, Alessandra Renieri, Alicia R. Martin, Benjamin M. Neale, Kristian Hveem, Reedik Mägi, Aarno Palotie, Henrike Heyne, Nina Mars, Andrea Ganna, Samuli Ripatti
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Polygenic scores (PGSs) offer the ability to predict genetic risk for complex diseases across the life course; a key benefit over short-term prediction models. To produce risk estimates relevant to clinical and public health decision-making,
Externí odkaz:
https://doaj.org/article/dc912c91250843ceb044717d0c5c8972
Publikováno v:
Frontiers in Sports and Active Living, Vol 6 (2024)
IntroductionSchool day structure has the potential to increase students’ physical activity (PA) levels and form positive attitudes about PA. Including various PA opportunities and free play possibilities in the school schedule, especially outdoor r
Externí odkaz:
https://doaj.org/article/201732b5638a44dab0e28a642fdb8800
Autor:
Anette Kalnapenkis, Maarja Jõeloo, Kaido Lepik, Viktorija Kukuškina, Mart Kals, Kaur Alasoo, Estonian Biobank Research Team, Reedik Mägi, Tõnu Esko, Urmo Võsa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract The proteome holds great potential as an intermediate layer between the genome and phenome. Previous protein quantitative trait locus studies have focused mainly on describing the effects of common genetic variations on the proteome. Here, w
Externí odkaz:
https://doaj.org/article/ae9bbd01cfa44bda98153108e362f918
Autor:
Pasanen, Anu, Sliz, Eeva, Huilaja, Laura, Reimann, Ene, Mägi, Reedik, Laisk, Triin, Tasanen, Kaisa, Kettunen, Johannes
Publikováno v:
In Journal of Investigative Dermatology November 2024 144(11):2417-2425
Autor:
Kharis Burns, Benjamin H. Mullin, Loes M. E. Moolhuijsen, Triin Laisk, Jaakko S. Tyrmi, Jinrui Cui, Ky’Era V. Actkins, Yvonne V. Louwers, Estonian Biobank Research Team, Lea K. Davis, Frank Dudbridge, Ricardo Azziz, Mark O. Goodarzi, Hannele Laivuori, Reedik Mägi, Jenny A. Visser, Joop S. E. Laven, Scott G. Wilson, FinnGen, International PCOS Consortium, Felix R. Day, Bronwyn G. A. Stuckey
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Polycystic ovary syndrome (PCOS) is a complex multifactorial disorder with a substantial genetic component. However, the clinical manifestations of PCOS are heterogeneous with notable differences between lean and obese women, impl
Externí odkaz:
https://doaj.org/article/12ed433e07ee4203bfbf1a390a901060
Autor:
Chiara Auwerx, Maarja Jõeloo, Marie C. Sadler, Nicolò Tesio, Sven Ojavee, Charlie J. Clark, Reedik Mägi, Estonian Biobank Research Team, Alexandre Reymond, Zoltán Kutalik
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-24 (2024)
Abstract Background Copy-number variations (CNVs) have been associated with rare and debilitating genomic disorders (GDs) but their impact on health later in life in the general population remains poorly described. Methods Assessing four modes of CNV
Externí odkaz:
https://doaj.org/article/99204a983c254d6594fd32cb0289dd83
Autor:
Mägi, Liisi, Uibu, Ere, Moi, Asgjerd Litleré, Mortensen, Michael, Naustdal, Kristin, Põlluste, Kaja, Lember, Margus, Kangasniemi, Mari
Publikováno v:
In Nurse Education Today August 2024 139