Výsledky vyhledávání - "A M, Theodosiou"

RETRACTED: Folic acid mediated endocytosis enhanced by modified multi stimuli nanocontainers for cancer targeting and treatment: Synthesis, characterization, in-vitro and in-vivo evaluation of therapeutic efficacy

Autor: Nikolaos Kostomitsopoulos, Pavlos Lelovas, Eleni K. Efthimiadou, A.L. Tziveleka, Nikos Boukos, Eirini Fragogeorgi, M. Theodosiou, V. Balafas, G. Kordas, George Loudos

Publikováno v: Journal of Drug Delivery Science and Technology. 55:101481

Polymeric materials are in the epicenter of scientific research the last decade and have been used in a range of pharmaceutical and biological applications. Multifunctional polymeric materials are capable targeting agents, which can be used as contro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d4b2d070baaed635ad153925f3f2e59
https://doi.org/10.1016/j.jddst.2019.101481

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A member of the MAP kinase phosphatase gene family in mouse containing a complex trinucleotide repeat in the coding region

Autor: M.A. Nesbit, H. Paterson, Nicholas Owen, Yvonne Boyd, E. McLellan-Arnold, Nanda R. Rodrigues, Kay E. Davies, M. A. Leversha, Derek J. Blake, A M Theodosiou, Alan Ashworth, Helen J. Ambrose

We have identified a novel mouse gene encoding a protein that shows high homology to the dual-specificity tyrosine/threonine phosphatase family of proteins. The gene encodes a 5 kb transcript which is expressed predominantly in brain and lung and con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6f10240dab70300f34325b4daad969
https://doi.org/10.1093/hmg/5.5.675

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Characterization of Ngef, a novel member of the Dbl family of genes expressed predominantly in the caudate nucleus

Autor: L Campbell, A M Theodosiou, D Saranath, A T Tandle, Kay E. Davies, Nanda R. Rodrigues, M.A. Nesbit

We have identified Ngef as a novel member of the family of Dbl genes. Many members of this family have been shown to function as guanine nucleotide exchange factors for the Rho-type GTPases. Ngef is predominantly expressed in brain, with the stronges

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa5a9803851909943bcbeb41a4022a7
https://ora.ox.ac.uk/objects/uuid:64f912a7-0731-42ad-a0a7-c33ee6cd3400

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Genomic Organization and Chromosomal Localization of a Member of the MAP Kinase Phosphatase Gene Family to Human Chromosome 11p15.5 and a Pseudogene to 10q11.2

Autor: A M Theodosiou, L Campbell, Peter Little, T.M.A.M.O. de Meulemeester, Kevin Talbot, Marielle Alders, Matthew D. Hodges, Yusuke Nakamura, Nanda R. Rodrigues, M.A. Mannens, M.A. Nesbit, Kay E. Davies

Publikováno v: Genomics, 42(2), 284-294. Academic Press Inc.

Mitogen-activated protein kinase phosphatases (MKPs) play a central role in a variety of signaling pathways. We recently described a novel murine MKP, M3/6, which is uniquely specific for c-Jun N-terminal kinase/stress-activated protein kinase and p3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843dcf287550a8cde8a5e194217e6a36
https://doi.org/10.1006/geno.1997.4737

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1458 Development, Evaluation and Application of a Web-Based Immunization Registry System

Autor: M Theodosiou, John Mantas, E Velonakis, Marianna Diomidous

Publikováno v: Pediatric Research. 68:720-721

Vaccination decreases children mortality and its' application, especially in the developing world, is a means towards the achievement of the United Nations Millennium Development Goals. Objects: We sought to develop, apply and, evaluate a web-based i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e6dd04d0a770b58d23cae7e68670229
https://doi.org/10.1203/00006450-201011001-01458

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Missense mutation clustering in the survival motor neuron gene: a role for a conserved tyrosine and glycine rich region of the protein in RNA metabolism?

Autor: Nanda R. Rodrigues, Robert Surtees, Chris P. Ponting, A M Theodosiou, Kevin Talbot, Kay E. Davies, Roger Mountford

Publikováno v: Human molecular genetics. 6(3)

The Survival Motor Neuron (SMN) gene shows deletions in the majority of patients with Spinal Muscular Atrophy (SMA), a disease of motor neuron degeneration. To date only two missense mutations have been reported in SMN in patients with SMA. The fact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f29e223dff95ecf5574b037f06e2840
https://pubmed.ncbi.nlm.nih.gov/9147655

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Complex repetitive arrangements of gene sequence in the candidate region of the spinal muscular atrophy gene in 5q13

Autor: A M, Theodosiou, K E, Morrison, A M, Nesbit, R J, Daniels, L, Campbell, M J, Francis, Z, Christodoulou, K E, Davies

Publikováno v: American journal of human genetics. 55(6)

Childhood-onset proximal spinal muscular atrophy (SMA) is a heritable neurological disorder, which has been mapped by genetic linkage analysis to chromosome 5q13, in the interval between markers D5S435 and D5S557. Here, we present gene sequences that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3961741ea01d8769487c0438d00315d7
https://pubmed.ncbi.nlm.nih.gov/7977382

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