Zobrazeno 1 - 10
of 134
pro vyhledávání: '"A M, Tartakoff"'
Autor:
Alan M. Tartakoff
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Bidirectional transport of macromolecules occurs through nuclear pores, which were first detected by electron microscopy. Interest in regulation of gene expression, curiosity to understand one of the few remaining uncharacterized translocons of eukar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea3e91b1334445e3cc4573c2635cbee3
https://doi.org/10.1016/b978-0-12-821618-7.00131-0
https://doi.org/10.1016/b978-0-12-821618-7.00131-0
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174306 (2017)
Cell cycle arrest can be imposed by inactivating the anaphase promoting complex (APC). In S. cerevisiae this arrest has been reported to stabilize a metaphase-like intermediate in which the nuclear envelope spans the bud neck, while chromatin repeate
Externí odkaz:
https://doaj.org/article/8f1ce2f8207644bf885ab7b9e3b37977
Autor:
Samantha Lin, Suchita Rajan, Sofia Lemberg, Mark Altawil, Katherine Anderson, Ruth Bryant, Sebastian Cappeta, Brandon Chin, Isabella Hamdan, Annelise Hamer, Rachel Hyzny, Andrew Karp, Daniel Lee, Alexandria Lim, Medha Nayak, Vishnu Palaniappan, Soomin Park, Sarika Satishkumar, Anika Seth, Uva Sri Dasari, Emili Toppari, Ayush Vyas, Julianne Walker, Evan Weston, Atif Zafar, Cecelia Zielke, Ganapati H Mahabeleshwar, Alan M Tartakoff
Publikováno v:
Genetics
35S rRNA transcripts include a 5′-external transcribed spacer followed by rRNAs of the small and large ribosomal subunits. Their processing yields massive precursors that include dozens of assembly factor proteins. In Saccharomyces cerevisiae, nucl
Autor:
Chun-Lun Ni, Divya Seth, Fabio Vasconcelos Fonseca, Liwen Wang, Tsan Sam Xiao, Phillip Gruber, Man-Sun Sy, Jonathan S Stamler, Alan M Tartakoff
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163359 (2016)
Expansion of the polyglutamine (polyQ) tract in the huntingtin (Htt) protein causes Huntington's disease (HD), a fatal inherited movement disorder linked to neurodegeneration in the striatum and cortex. S-nitrosylation and S-acylation of cysteine res
Externí odkaz:
https://doaj.org/article/891fafcf6a7e44d395d915576896eb75
Autor:
Alan M. Tartakoff, Di Wu
Publikováno v:
Cancer Informatics, Vol 13s6 (2014)
Starting with genetic or environmental perturbations, disease progression can involve a linear sequence of changes within individual cells. More often, however, a labyrinth of branching consequences emanates from the initial events. How can one repai
Externí odkaz:
https://doaj.org/article/4cfe6c1509a9400f82f29f9d5e7af48f
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54245 (2013)
Although P. aeruginosa is especially dangerous in cystic fibrosis (CF), there is no consensus as to how it kills representative cell types that are of key importance in the lung. This study concerns the acute toxicity of the sequenced strain, PAO1, t
Externí odkaz:
https://doaj.org/article/5e91ed48354b4d0c999827a469f4e957
Publikováno v:
Genetics. 208:139-151
We have investigated an extreme deviation from the norm of genome unification that occurs during mating in the yeast, Saccharomyces cerevisiae. This deviation is encountered when yeast that carry a mutation of the spindle pole body protein, Kar1, are
Autor:
Alan M. Tartakoff
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100736-(2021)
Summary It is often necessary to learn whether macromolecules occupy a fixed place in cells. This protocol makes it possible to learn whether individual nucleolar proteins in S. cerevisiae remain in place or depart from and return to the nucleolus. T
Autor:
Alan M. Tartakoff
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100646-(2021)
Summary S. cerevisiae can be arrested in metaphase by depleting Cdc20. We describe (1) how to achieve this arrest and verify it, (2) how to label cell surface glycans covalently to distinguish mother from bud, and (3) how to detect the nucleolus and
Autor:
Lan Chen, Cassandra Pasadyn, Alan M. Tartakoff, John L. Woolford, Ganapati H. Mahabeleshwar, Shashank Raghavachari, Akshyasri Dhinakaran, Chun Lun Ni, Vanessa Pasadyn, Daria Gitiforooz
Publikováno v:
Curr Biol
Summary In ribosomal DNA (rDNA) repeats, sequences encoding small-subunit (SSU) rRNA precede those encoding large-subunit (LSU) rRNAs. Processing the composite transcript and subunit assembly requires >100 subunit-specific nucleolar assembly factors