Zobrazeno 1 - 10
of 28
pro vyhledávání: '"A M, Shadiack"'
Autor:
Toby A Silverman, Annette M Shadiack, Kimberly A Hofmeyer, Ashley E Cecere, Derek L Eisnor, Corey M Hoffman, Shannon G Loelius, Aditiben Patel, Mary J Homer
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 9, Iss Suppl 1 (2024)
Externí odkaz:
https://doaj.org/article/de1effdc1c08462fb777ccfd7a3f78ed
Autor:
James A. Simon, Sebastian Mirkin, Shelli Graham, James H. Pickar, Bharat Warrier, Annette M. Shadiack, Brian Bernick
Publikováno v:
Menopause (New York, N.y.)
Objective: TX-004HR is a low-dose estradiol (E2) softgel vaginal insert designed to be rapidly dissolving and mucoadhesive. This report describes the physical attributes and pharmacokinetic parameters of the softgel vaginal insert evaluated for the t
Autor:
James H. Liu, Ginger D. Constantine, Rogerio A. Lobo, Brian Bernick, Sebastian Mirkin, James H. Pickar, Annette M. Shadiack, Frank Z. Stanczyk
Publikováno v:
Menopause (New York, N.y.)
Objective: In the REPLENISH trial, women receiving TX-001HR—an oral, softgel capsule, combining 17β-estradiol (E2) and progesterone (E2 mg/P4 mg 1/100, 0.5/100), had significantly improved vasomotor symptoms, while having their endometrium protect
Autor:
Jonathan French, Alan C. Fisher, Brent J. Yamamoto, Natalya V. Serbina, Nestor Gonzales, Edward O'Connor, Lisa N. Henning, Annette M. Shadiack, Daniel C. Sanford, Sarah Carpenter, Gregory V. Stark, John Mondick, Leslie S. Casey
Publikováno v:
Antimicrobial Agents and Chemotherapy
Inhalational anthrax has high mortality even with antibiotic treatment, and antitoxins are now recommended as an adjunct to standard antimicrobial regimens. The efficacy of obiltoxaximab, a monoclonal antibody against anthrax protective antigen (PA),
Autor:
Daniel C. Sanford, Sarah Carpenter, Lisa N. Henning, Natalya V. Serbina, Nestor Gonzales, Edward O'Connor, Leslie S. Casey, Annette M. Shadiack, Brent J. Yamamoto
Publikováno v:
Antimicrobial Agents and Chemotherapy
The Centers for Disease Control and Prevention recommend adjunctive antitoxins when systemic anthrax is suspected. Obiltoxaximab, a monoclonal antibody against protective antigen (PA), is approved for treatment of inhalational anthrax in combination
Autor:
David F. Archer, James H. Pickar, Ginger D. Constantine, Annette M. Shadiack, Brian Bernick, Sebastian Mirkin
Publikováno v:
Menopause (New York, N.Y.). 25(8)
Publikováno v:
Current Topics in Medicinal Chemistry. 7:1137-1144
Melanocortinergic agents are currently being investigated for a possible therapeutic role in male and female sexual dysfunction. These investigations were sparked by findings that systemic administration of a synthetic analog of alpha-MSH, MT-II, cau
Publikováno v:
Drug Discovery Today: Therapeutic Strategies. 3:605-611
Sexual dysfunction affects millions of men and women worldwide. Preclinical and clinical studies demonstrate and confirm that melanocortin receptor agonists such as bremelanotide (PT141, a synthetic alpha-melanocyte stimulating hormone analog) improv
Publikováno v:
International Journal of Impotence Research. 16:135-142
PT-141, a cyclic heptapeptide melanocortin analog, was evaluated following subcutaneous administration to healthy male subjects and to patients with erectile dysfunction (ED) who report an inadequate response to Viagra. An inadequate response was def
Publikováno v:
Annals of the New York Academy of Sciences. 994:96-102
PT-141, a synthetic peptide analogue of alpha-MSH, is an agonist at melanocortin receptors including the MC3R and MC4R, which are expressed primarily in the central nervous system. Administration of PT-141 to rats and nonhuman primates results in pen