Zobrazeno 1 - 10
of 458
pro vyhledávání: '"A M, Scherbakov"'
Autor:
A. Lee, T. A. Bogush, A. N. Grishanina, I. P. Romanov, E. A. Bogush, S. A. Kaliuzhny, K. I. Chandran, A. M. Scherbakov, V. S. Kosorukov
Publikováno v:
Антибиотики и Химиотерапия, Vol 69, Iss 5-6, Pp 28-34 (2024)
Background. The cytoskeletal protein β-tubulin class III (Tubb3) is associated with tumor resistance to taxanes and vinca alkaloids, as well as with the metastatic potential of neoplasm, however, data from immunohistochemical analysis of Tubb3 expre
Externí odkaz:
https://doaj.org/article/0555cd44bacb4de28f772016a8bfef2f
Autor:
I. P. Romanov, T. A. Bogush, A. M. Scherbakov, A. A. Alimov, E. A. Bogush, A. B. Ravcheeva, A. Lee, V. S. Kosorukov
Publikováno v:
Антибиотики и Химиотерапия, Vol 69, Iss 1-2, Pp 29-36 (2024)
Background. Progesterone receptors (PR) are regulators of cell proliferation and therefore can be considered as an aim for targeted medications in the treatment of oncological diseases. At the same time, a quantitative assessment of PR expression in
Externí odkaz:
https://doaj.org/article/f81b3dbafd994c15b83ca033a4c0bdaf
Autor:
O. E. Andreeva, D. V. Sorokin, S. V. Vinokurova, Yu. Yu. Shchegolev, N. V. Elkina, A. N. Katargin, R. S. Faskhutdinov, D. I. Salnikova, A. M. Scherbakov, M. A. Krasil’nikov
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 4, Pp 149-156 (2023)
Introduction. Rearrangement of molecular pathways and activation of bypass signaling determine the progression of tumor cell resistance to various drugs. Study of the common features of resistant formation mechanisms is essential for breast and other
Externí odkaz:
https://doaj.org/article/e6ac69de32684d978a782743306a0325
Autor:
D. V. Sorokin, O. E. Andreeva, A. M. Scherbakov, D. I. Salnikova, M. V. Gudkova, M. A. Krasil’nikov
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 4, Pp 108-115 (2023)
Introduction. The study of the effect of irradiation or any other DNA-damaging agents on the sensitivity of tumors to conservative therapy, drug or hormonal, is among the most imporant tasks that determine the efficiency of combined therapy of cancer
Externí odkaz:
https://doaj.org/article/e5ff026858854d6c913023acd0a998d1
Autor:
Yu. Yu. Shchegolev, M. A. Karpukhina, D. V. Sorokin, A. M. Scherbakov, O. E. Andreeva, V. E. Razuvaeva, T. A. Bogush, I. N. Mikhaylova, L. V. Demidov, M. V. Gudkova, M. A. Krasil’nikov
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 3, Pp 50-58 (2023)
Introduction. Melanoma belongs to the group of the most malignant tumors characterized by aggressive growth and active metastasis. At the same time, the effectiveness of therapy, primarily targeted therapy, is largely limited by the rapid development
Externí odkaz:
https://doaj.org/article/94aa493afae74c17a55cd214163d9cbc
Autor:
T. A. Bogush, P. D. Potselueva, A. M. Scherbakov, E. A. Bogush, A. B. Ravcheeva, N. O. Vikhlyantseva, V. S. Kosorukov
Publikováno v:
Антибиотики и Химиотерапия, Vol 68, Iss 3-4, Pp 39-45 (2023)
Background. Estrogen receptors beta (ERβ) are an important biological regulator and target of antiestrogens, however, unlike estrogen receptors alpha (ERɑ), their significance in the prognosis and treatment of breast cancer remains unclear. Purpose
Externí odkaz:
https://doaj.org/article/00e296c6a91b4121835632d7739bf5a6
Autor:
Yuri Yu. Shchegolev, Danila V. Sorokin, Alexander M. Scherbakov, Olga E. Andreeva, Diana I. Salnikova, Ekaterina I. Mikhaevich, Margarita V. Gudkova, Mikhail A. Krasil’nikov
Publikováno v:
BioImpacts, Vol 13, Iss 4, Pp 313-321 (2023)
Introduction: Resistance to chemotherapy and/or irradiation remains one of the key features of malignant tumors, which largely limits the efficiency of antitumor therapy. In this work, we studied the progression mechanism of breast cancer cell resist
Externí odkaz:
https://doaj.org/article/beb324107022466888a107ab710c0b69
Autor:
Diana I. Salnikova, Stepan K. Krymov, Danila V. Sorokin, Fedor B. Bogdanov, Olga E. Andreeva, Alvina I. Khamidullina, Andrey E. Shchekotikhin, Alexander M. Scherbakov
Publikováno v:
Proceedings, Vol 100, Iss 1, p 4 (2024)
Introduction: The design and development of antitumor compounds based on an isatin core led to the synthesis of 1-substituted isatin-5-sulfonamides with potent antiproliferative activity [...]
Externí odkaz:
https://doaj.org/article/1374ebb7d9014592ae7a54f751b6d95c
Autor:
Alexander M. Scherbakov, Yury V. Kuznetsov, Margarita A. Yastrebova, Alvina I. Khamidullina, Danila V. Sorokin, Maria O. Tserfas, Inna S. Levina
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 59 (2023)
Abstract This study aimed to investigate the activities of novel 20(R)-3,20-dihydroxy-19-norpregn-1,3,5(10)-trienes (kuz7 and kuz8b) of natural 13β- and epimeric 13α-series against triple-negative MDA-MB-231 breast cancer cells. High antiproliferat
Externí odkaz:
https://doaj.org/article/a5b97f58a4994fa2b5e96bd91cac2bbc
Autor:
A. M. Scherbakov, T. I. Fetisov, D. V. Sorokin, V. Yu. Zinovieva, N. I. Moiseeva, L. A. Laletina, E. M. Kirilin, A. E. Manikaylo, L. Ya. Fomina, L. V. Mekheda, B. Yu. Bokhyan, E. A. Lesovaya, L. S. Trukhanova, T. G. Gor’kova, E. E. Antoshina, O. V. Morozova, K. I. Kirsanov, M. G. Yakubovskaya
Publikováno v:
Успехи молекулярной онкологии, Vol 9, Iss 2, Pp 58-65 (2022)
Introduction. The identification of predictive factors is a cornerstone task of modern oncology. The development of new targeted drugs determines the need for prediction of chemosensitivity of each patient to the prescribed therapy, in this regard, t
Externí odkaz:
https://doaj.org/article/71afdbbddba344529bf70f023fe79b06