Zobrazeno 1 - 10
of 25
pro vyhledávání: '"A M, Sarrif"'
Publikováno v:
Drug and chemical toxicology. 29(2)
Male and female mice, rats, hamsters, and rabbits were treated with a single oral dose of 14C-ammonium perfluorooctanoate (APFO), and the excretion and tissue distributions were followed for 120 h (168 h in the rabbit). Substantial sex and species di
Autor:
L B, Vogler, W M, Crist, A M, Sarrif, D J, Pullen, A A, Bartolucci, J M, Falletta, B, Dowell, G B, Humphrey, R, Blackstock, J, van Eys, R S, Metzgar, M D, Cooper
Publikováno v:
Blood. 58:135-140
In 35 of 191 patients with acute lymphocytic leukemia (ALL) malignant cells were similar in phenotype to B-lymphocyte precursors. Both these patients' lymphoblasts and normal pre-B-cells contain cytoplasmic immunoglobulin (Ig) mu heavy chains, but ha
Publikováno v:
Biochemical Pharmacology. 29:1059-1063
Several 2,4-pyrimidinedione (uracil) derivatives were evaluated as inhibitors of the pyrimidine nucleoside phosphorylases that cleave 5-fluorn-2'-deoxyuridine (FUdR) to 5-fluorouracil. Pyrimidinediones substituted at either N-1 or C-5, or both, marke
Autor:
John R. Durant, Awni M. Sarrif
Publikováno v:
Cancer. 48:1215-1220
A small number of primary metastatic breast carcinomas are estrogen-receptor-negative and progesterone-receptor-positive (ER-, PGR+) under the normal ligand-binding assay or sucrose density gradient conditions. Among more than 500 tumors analyzed in
Publikováno v:
In Vitro. 16:541-546
When photolyzed in situ for as little as 15 s 2-azido-9-fluorenone oxime causes Type II and Type III transformation in C3H 10T 1/2 CL8 cells. In the yeast strain Saccharomyces cerevisiae D-7, simple reversions and gene conversions occurred and also m
Publikováno v:
Cancer Letters. 13:291-297
Since it has been shown that transformation frequencies (TF) of cultured mammalian cells exposed to polycyclic aromatic hydrocarbons (PAH) reach a maximum with increasing PAH concentration and then decline, we have examined TF in C3H 10T1/2 CL8 (10T1
Publikováno v:
Biochemical and Biophysical Research Communications. 70:869-877
There is a protein moiety in the C3H mouse liver cytosol which gives a line of identity with rat liver ligandin one of three azo dye binding proteins of the liver using anti-rat ligandin. This mouse liver protein has been termed mouse ligandin and is
Publikováno v:
Archives of Biochemistry and Biophysics. 162:421-425
23Sodium binding to a partially purified beef brain and purified dogfish rectal gland (sodium + potassium)-activated adenosinetriphosphatase (NaK ATPase) has been studied by pulsed nmr. In both preparations addition of ATP (in the absence of Mg) incr
Publikováno v:
Journal of Pharmaceutical Sciences. 61:1311-1313
A procedure for the determination of aqueous solutions of scopolamine and its acidic and basic degradation products is given. Liquid-liquid partition chromatography is used to remove the compounds quantitatively from aqueous solution. After preparati
Publikováno v:
Biochemical and biophysical research communications. 83(2)
2-Azidofluorene was synthesized to serve as a specific photoaffinity label in chemical carcinogenesis studies. The drug exhibited little toxicity, and was non-transforming in the C3H 10T 1 2 CL8 cells. When photolysed at 360 nm in water to generate N