Zobrazeno 1 - 10
of 10
pro vyhledávání: '"A M, Pliakas"'
Autor:
Anna B. Rachlin, William A. Carlezon, Allison M. Sawyer, Dave Potter, Andrea M. Pliakas, Elena H. Chartoff
Publikováno v:
Neuropharmacology. 62:167-176
Drug dependence is characterized by dysregulation of brain reward systems and increased sensitivity to stress. Chronic exposure to drugs of abuse is associated with increased expression of the neuropeptide dynorphin, the endogenous ligand for kappa o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec4e41ddccbb60e9c80aa8d51d1664c
https://doi.org/10.1016/j.neuropharm.2011.06.014
https://doi.org/10.1016/j.neuropharm.2011.06.014
Autor:
William A. Carlezon, William C. Stevens, Mark S. Todtenkopf, Philip S. Portoghese, Hilarie C. Tomasiewicz, Stephen D. Mague, Andrea M. Pliakas, Robert M. Jones, Yan Zhang
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 305:323-330
We showed previously that cAMP response element-binding protein (CREB) within the nucleus accumbens (NAc) of rats regulates immobility in the forced swim test (FST), an assay used to study depression. Because CREB regulates expression of dynorphin (w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae753f33bfc920bd5ff351bed680682d
https://doi.org/10.1124/jpet.102.046433
https://doi.org/10.1124/jpet.102.046433
Autor:
Rachael L. Neve, Christine Konradi, Andrea M. Pliakas, Eric J. Nestler, Richard R. Carlson, William A. Carlezon
Publikováno v:
The Journal of Neuroscience. 21:7397-7403
Drugs of abuse regulate the transcription factor cAMP response element-binding protein (CREB) in striatal regions, including the nucleus accumbens (NAc). To explore how regulation of CREB in the NAc affects behavior, we used herpes simplex virus (HSV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::077f34044559a8bcd7259bb1d0be2e10
https://doi.org/10.1523/jneurosci.21-18-07397.2001
https://doi.org/10.1523/jneurosci.21-18-07397.2001
Autor:
Sherese Ali, Stephen E. Nicolson, Jeff C. Huffman, Gregory L. Fricchione, Andrea M. Pliakas, Amanda Wilson, Charles A. Welch, Lawrence Park
Publikováno v:
Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology. 21(1)
To describe 2 cases of encephalitis with neuropsychiatric symptoms including catatonia, compounded by neuroleptic use for delirious agitation culminating in malignant catatonia responsive to electroconvulsive therapy (ECT).Neuropsychiatric symptoms i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4dde61655b540359b71d61fd031e01
https://pubmed.ncbi.nlm.nih.gov/18327024
https://pubmed.ncbi.nlm.nih.gov/18327024
Publikováno v:
Biological psychiatry. 59(12)
Background Calcium (Ca 2+ ) influx within the nucleus accumbens shell (NASh) can influence brain reward processes. We found previously that rats self-administer NMDA receptor antagonists (which block Ca 2+ influx through NMDA receptors) into the NASh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221de42dfbcde06c46bd91a083fd85ff
https://pubmed.ncbi.nlm.nih.gov/16458265
https://pubmed.ncbi.nlm.nih.gov/16458265
Autor:
Andrea M. Pliakas, Aimee Parow, Perry F. Renshaw, Michael J. Detke, William A. Carlezon, Bruce M. Cohen
Publikováno v:
Biological psychiatry. 51(11)
Background: Altered brain phospholipid metabolism may be involved in the pathophysiology of cocaine dependence and mood disorders. Evidence suggests that citicoline, a rate-limiting metabolite for phospholipid synthesis, reduces cocaine craving in hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae38b3af3393d53f465644d87b035859
https://pubmed.ncbi.nlm.nih.gov/12022961
https://pubmed.ncbi.nlm.nih.gov/12022961
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 21(18)
Drugs of abuse regulate the transcription factor cAMP response element-binding protein (CREB) in striatal regions, including the nucleus accumbens (NAc). To explore how regulation of CREB in the NAc affects behavior, we used herpes simplex virus (HSV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e435a2884bb921b10cc671eeac9f0fd
https://pubmed.ncbi.nlm.nih.gov/11549750
https://pubmed.ncbi.nlm.nih.gov/11549750
Autor:
Andrea M. Pliakas, Mark S. Todtenkopf, William A. Carlezon, James R. Stellar, Monika Trzcinska, Patricia Pimentel, Donna L. McPhie
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 25(2)
There is considerable evidence that drug reward and brain stimulation reward (BSR) share common neural substrates. Although it is known that exposure to drugs of abuse causes a variety of molecular changes in brain reward systems, little is known abo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bae9fe8284f649612c5b5a156038d18
https://pubmed.ncbi.nlm.nih.gov/11425507
https://pubmed.ncbi.nlm.nih.gov/11425507
Autor:
Andrea M. Pliakas, Celeste J. LeBlanc, Andreas Arvanitogiannis, Susan L. Andersen, William A. Carlezon
Publikováno v:
Nature Neuroscience. 5:13-14
Evidence in laboratory animals indicates that exposure to stimulants produces sensitization to their rewarding effects, a process that in humans would be expected to increase the risk of substance abuse. However, therapeutic administration of stimula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca41cc131198b54ee59ee706f457215
https://doi.org/10.1038/nn777
https://doi.org/10.1038/nn777
Autor:
D, Mague Stephen, M, Pliakas Andrea, S, Todtenkopf Mark, C, Tomasiewicz Hilarie, Yan, Zhang, C, Stevens William, M, Jones Robert, S, Portoghese Philip, A, Carlezon William
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; April 2003, Vol. 305 Issue: 1 p323-30, 8p