Zobrazeno 1 - 10
of 116
pro vyhledávání: '"A M, Pendás"'
Autor:
Elena Llano, Alberto M. Pendás
Publikováno v:
Cells, Vol 12, Iss 13, p 1718 (2023)
The synaptonemal complex (SC) is a meiosis-specific multiprotein complex that forms between homologous chromosomes during prophase of meiosis I. Upon assembly, the SC mediates the synapses of the homologous chromosomes, leading to the formation of bi
Externí odkaz:
https://doaj.org/article/b21e48184a4f43a0aaf084a4dc75f490
Autor:
Fernando Sánchez-Sáez, Raquel Sainz-Urruela, Natalia Felipe-Medina, Yazmine B. Condezo, Manuel Sánchez-Martín, Elena Llano, Alberto M. Pendás
Publikováno v:
Cells, Vol 11, Iss 22, p 3706 (2022)
Meiosis is a highly conserved specialized cell division process that generates haploid gametes. Many of its events are associated with dynamically regulated chromosomal structures and chromatin remodeling, which are mainly modulated by histone modifi
Externí odkaz:
https://doaj.org/article/7bf345bdb42a4b218aed5460b1545e54
Autor:
Monica M. Franca, Yazmine B. Condezo, Maëva Elzaiat, Natalia Felipe-Medina, Fernando Sánchez-Sáez, Sergio Muñoz, Raquel Sainz-Urruela, M. Rosario Martín-Hervás, Rodrigo García-Valiente, Manuel A. Sánchez-Martín, Aurora Astudillo, Juan Mendez, Elena Llano, Reiner A. Veitia, Berenice B. Mendonca, Alberto M. Pendás
Publikováno v:
Cell death and differentiation, 29(12), 2347-2361. Nature Publishing Group
Primary ovarian insufficiency (POI) causes female infertility by abolishing normal ovarian function. Although its genetic etiology has been extensively investigated, most POI cases remain unexplained. Using whole-exome sequencing, we identified a hom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501488bc5590e517507781c687873ae1
http://www.scopus.com/inward/record.url?scp=85130757659&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85130757659&partnerID=8YFLogxK
Autor:
Natalia Felipe-Medina, Sandrine Caburet, Fernando Sánchez-Sáez, Yazmine B Condezo, Dirk G de Rooij, Laura Gómez-H, Rodrigo Garcia-Valiente, Anne Laure Todeschini, Paloma Duque, Manuel Adolfo Sánchez-Martin, Stavit A Shalev, Elena Llano, Reiner A Veitia, Alberto M Pendás
Publikováno v:
eLife, Vol 9 (2020)
Primary Ovarian Insufficiency (POI) is a major cause of infertility, but its etiology remains poorly understood. Using whole-exome sequencing in a family with three cases of POI, we identified the candidate missense variant S167L in HSF2BP, an essent
Externí odkaz:
https://doaj.org/article/26db10f852a84974ae97f713af8a613d
Autor:
Covadonga Vara, Andreu Paytuví-Gallart, Yasmina Cuartero, François Le Dily, Francisca Garcia, Judit Salvà-Castro, Laura Gómez-H, Eva Julià, Catia Moutinho, Riccardo Aiese Cigliano, Walter Sanseverino, Oscar Fornas, Alberto M. Pendás, Holger Heyn, Paul D. Waters, Marc A. Marti-Renom, Aurora Ruiz-Herrera
Publikováno v:
Cell Reports, Vol 28, Iss 2, Pp 352-367.e9 (2019)
Summary: Mammalian gametogenesis involves dramatic and tightly regulated chromatin remodeling, whose regulatory pathways remain largely unexplored. Here, we generate a comprehensive high-resolution structural and functional atlas of mouse spermatogen
Externí odkaz:
https://doaj.org/article/2cbed9e3280e4e989c539103b74b87fb
Autor:
Eva M. Rico-Leo, Nuria Moreno-Marín, Francisco J. González-Rico, Eva Barrasa, Cristina Ortega-Ferrusola, Patricia Martín-Muñoz, Luis O. Sánchez-Guardado, Elena Llano, Alberto Alvarez-Barrientos, Ascensión Infante-Campos, Inmaculada Catalina-Fernández, Matías Hidalgo-Sánchez, Dirk G. de Rooij, Alberto M. Pendás, Fernando J. Peña, Jaime M. Merino, Pedro M. Fernández-Salguero
Publikováno v:
Open Biology, Vol 6, Iss 12 (2016)
Previous studies suggested that the aryl hydrocarbon receptor (AhR) contributes to mice reproduction and fertility. However, the mechanisms involved remain mostly unknown. Retrotransposon silencing by Piwi-interacting RNAs (piRNAs) is essential for g
Externí odkaz:
https://doaj.org/article/477a439f0e0e40e4a76278073e1b59c0
Autor:
Erica Hurtado, Miguel A. Peinado, Lauro Sumoy, Yaiza Núñez-Álvarez, Raquel Pluvinet, Gabriel E. Rech, Ignacio García-Tuñón, Mar Muñoz, Alberto M. Pendás, Mònica Suelves
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Histone deacetylase 11 (HDAC11) is the latest identified member of the histone deacetylase family of enzymes. It is highly expressed in brain, heart, testis, kidney, and skeletal muscle, although its role in these tissues is poorly understood. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef793cdbe3db8066dc53fbd69b1e808
https://doi.org/10.1111/febs.15468
https://doi.org/10.1111/febs.15468
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Separation of eukaryotic sister chromatids during the cell cycle is timed by the spindle assembly checkpoint (SAC) and ultimately triggered when separase cleaves cohesion-mediating cohesin1,2,3. Silencing of the SAC during metaphase activates the ubi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebf8d2def5aa41521d6d9562e11927f
https://doi.org/10.1038/s41586-020-2182-3
https://doi.org/10.1038/s41586-020-2182-3
Autor:
Marie-Hélène Le Du, Maarten W. Paul, Roland Kanaar, Esther Sleddens-Linkels, Rania Ghouil, Alberto M. Pendás, Pierre Legrand, Lieke Koornneef, Yvette van Loon, Natalia Felipe-Medina, Jasper Veerman, Alex N. Zelensky, Jeroen Essers, Willy M. Baarends, Sari E. van Rossum-Fikkert, Sophie Zinn-Justin, Alex Maas, Simona Miron
Publikováno v:
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, 12(1):4605. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, 12(1):4605. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
© The Author(s) 2021.
BRCA2 and its interactors are required for meiotic homologous recombination (HR) and fertility. Loss of HSF2BP, a BRCA2 interactor, disrupts HR during spermatogenesis. We test the model postulating that HSF2BP localizes BR
BRCA2 and its interactors are required for meiotic homologous recombination (HR) and fertility. Loss of HSF2BP, a BRCA2 interactor, disrupts HR during spermatogenesis. We test the model postulating that HSF2BP localizes BR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b99781f32df629289d3166479d9c2f
https://doi.org/10.1038/s41467-021-24871-6
https://doi.org/10.1038/s41467-021-24871-6
Autor:
Roland Kanaar, Pierre Legrand, Alex Maas, Simona Miron, Maarten W. Paul, Rania Ghouil, Lieke Koornneef, Alberto M. Pendás, Jasper Veerman, Esther Sleddens-Linkels, Sari E. van Rossum-Fikkert, Marie-Hélène Le Du, Sophie Zinn-Justin, Willy M. Baarends, Alex N. Zelensky, Jeroen Essers, Natalia Felipe-Medina, Yvette van Loon
BRCA2 plays a prominent role in meiotic homologous recombination (HR). Loss of BRCA2 or several of its meiotic partners causes fertility defects. One of these partners, HSF2BP, was recently discovered as expressed physiologically in germline and ecto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa2d17b626d9e0e3401e1933aa2123f1
https://doi.org/10.1101/2020.12.29.424679
https://doi.org/10.1101/2020.12.29.424679
