Mechanism of the slow induction of apolipoprotein A-I synthesis by retinoids in cynomolgus hepatocytes: involvement of retinoic acid and retinoid X receptors

Autor: A Kaptein, D M Neele, J Twisk, H F Hendriks, T Kooistra, H M Princen

Publikováno v: Journal of Lipid Research, Vol 38, Iss 11, Pp 2273-2280 (1997)

We showed previously that retinoids stimulate apolipoprotein A-I (apoA-I) synthesis in cultured cynomolgus hepatocytes only after a 24-h lag phase. Here we report on the biochemical background of the slow response, the requirement for high retinoic a

Externí odkaz: https://doaj.org/article/e181e109f44540baa5779cd0263f8168

Vascular calcification: expression patterns of the osteoblast-specific gene core binding factor alpha-1 and the protective factor matrix Gla protein in human atherogenesis

Autor: J. M. Neele, A.L.J.J. Bronckers, C. J. M. De Vries, Hans Pannekoek, Marten A. Engelse

Publikováno v: Engelse, M A, Neele, J M, Bronckers, A L J J, Pannekoek, H & de Vries, C J M 2001, ' Vascular calcification: expression patterns of the osteoblast-specific gene core binding factor alpha-1 and the protective factor matrix Gla protein in human atherogenesis ', Cardiovascular Research, vol. 52, pp. 281-289 . https://doi.org/10.1016/S0008-6363(01)00375-3
Cardiovascular Research, 52, 281-289. Oxford University Press
Cardiovascular research, 52, 281-289. Oxford University Press
Cardiovascular research, 52(2), 281-289. Oxford University Press

Objective: Increasing evidence suggests that vascular calcification is a regulated process. We studied the vascular expression pattern of a key factor in mineralization and a counteracting, protective factor. Based on the phenotype of null mice, Core

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b4ffcd75d188d81c359a4f55a88173
https://hdl.handle.net/11245/1.186672

A 6-year-old boy with hyperammonaemia

Autor: Jan A. Rauwerda, Marjo S. van der Knaap, Wim G. van Gemert, Daniël L. J. Broere, Radu A. Manoliu, C. M. Frank Kneepkens, Diana M. Neele

Publikováno v: European Journal of Pediatrics, 159(12), 905-907. Springer Verlag
Broere, D, Van Gemert, W G, Kneepkens, C M F, Neele, D M, Manoliu, R A, Rauwerda, J A & Van der Knaap, M S 2000, ' A 6-year-old boy with hyperammonaemia : Partial N-acetylglutamate synthase deficiency or portosystemic encephalopathy? ', European Journal of Pediatrics, vol. 159, no. 12, pp. 905-907 . https://doi.org/10.1007/PL00008367

We describe a 6-year-old boy admitted with lethargy and somnolence. Laboratory tests showed hyperammonaemia (arterial level 186 μmol/1) and slightly elevated prothrombin time. The patient was treated with sodium benzoate, lactulose and a protein-res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b562c2c7a86a83e9d488dd217801e1c
http://www.scopus.com/inward/record.url?scp=0033695766&partnerID=8YFLogxK

Oestrogen replacement therapy lowers plasma levels of asymmetrical dimethylarginine in healthy postmenopausal women

Autor: J. C. Netelenbos, S. J. M. Neele, S. De Jong, Tom Teerlink, Coen D.A. Stehouwer

Publikováno v: Clinical science (London, England : 1979). 105(1)

Oestrogen replacement therapy (ERT) has been shown to lead to favourable changes in the cardiovascular risk profile of postmenopausal women. Part of this effect is ascribed to increased production or bioavailability of nitric oxide (NO). We have test

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75084c980decd092947a38f568a8bc1d
https://pubmed.ncbi.nlm.nih.gov/12683948

Human activin-A is expressed in the atherosclerotic lesion and promotes the contractile phenotype of smooth muscle cells

Autor: T. A. E. Van Achterberg, R. van Schaik, Marten A. Engelse, Hans Pannekoek, C. J. M. De Vries, B. E. Van Aken, J. M. Neele

Publikováno v: Circulation Research, 85, 931-939. Lippincott Williams & Wilkins

Abstract —Activin is a member of the transforming growth factor-β superfamily, and it modulates the proliferation and differentiation of various target cells. In this study, we investigated the role of activin in the initiation and progression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::319bb638cd462eb68e9d4d82562d8507
https://pubmed.ncbi.nlm.nih.gov/10559140