Výsledky vyhledávání - "A M, Mezzasoma"

Analysis of 339 pregnancies in 181 women with 13 different forms of inherited thrombocytopenia

Autor: Paula G. Heller, Loredana Bury, Catherine Trichet, Nuria Pujol-Moix, Alessandro Pecci, Fabrizio Fabris, Maria Luigia Randi, Ana C. Glembotsky, Marco Cattaneo, Adam Cuker, Jeanne-Yvonne Borg, Nathalie Trillot, James B. Bussel, Patrizia Noris, E Muniz-Diaz, François Lanza, Lucia Dora Notarangelo, Dominique Martin-Coignard, Anne Bauters, Paolo Gresele, Thomas Lecompte, Catherine Klersy, Sandra Mercier, Giuseppe Loffredo, Marie-Françoise Hurtaud-Roux, Véronique Le Cam Duchez, Emanuela Falcinelli, Nicole Schlegel, Erica De Candia, Dino Veneri, Schéhérazade Benabdallah-Guedira, Fanny Menard, Catherine Pouymayou, Ilaria Nichele, Chloé James, Michela Faleschini, Elisa Civaschi, Caterina Marconi, Roberta Bottega, Tommaso Pippucci, Pierre Sié, Sophie Bayart, Béatrice Saposnik, Daniela De Rocco, Rémi Favier, Françoise Boehlen, Pierre Fontana, Alina Ferster, Anna Savoia, Carlo L. Balduini, Pamela Magini, Bruno Royer, Véronique Latger-Cannard, Alessandra Tucci, Dominique Fleury, Agnes Rigouzzo, Tiziana Fierro, Gian Marco Podda, Emmanuel de Maistre, Silvia Ferrari, Paquita Nurden, Pietro Minuz, Andreas Greinacher, Virginie Siguret, A. M. Mezzasoma

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
HAEMATOLOGICA
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Haematologica, Vol. 99, No 8 (2014) pp. 1387-94

Pregnancy in women with inherited thrombocytopenias is a major matter of concern as both the mothers and the newborns are potentially at risk of bleeding. However, medical management of this condition cannot be based on evidence because of the lack o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee02baeb355d1552e96f4249ac1853e
http://hdl.handle.net/11368/2846527

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In vivo platelet activation and platelet hyperreactivity in abacavir-treated HIV-infected patients

Autor: Silvia Giannini, Valentina Conti, Daniela Francisci, Franco Baldelli, Paolo Gresele, Stefano Bonora, A. M. Mezzasoma, Lisa Malincarne, Giuseppe Guglielmini, Barbara Belfiori, Manuela Sebastiano, Emanuela Falcinelli, Eleonora Petito

SummaryAbacavir (ABC) has been associated with ischaemic cardiovascular events in HIV-infected patients, but the pathogenic mechanisms are unknown. Aim of our study was to assess whether ABC induces in vivo platelet activation and ex vivo platelet hy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3fc28a470509e9e82d04135e975be69
http://hdl.handle.net/2318/147967

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Role of platelet activation in the cardiovascular complications associated with HIV infection: differential effect of abacavir versus tenofovir

Autor: M Mezzasoma, Barbara Belfiori, Franco Baldelli, Daniela Francisci, Paolo Gresele, Emanuela Falcinelli, Eleonora Petito

Publikováno v: Journal of the International AIDS Society

Abacavir use has been associated with an increased risk of ischemic cardiovascular events in several cohort studies, but the pathogenic mechanisms are still unknown. Recently Martinez et al. observed no differences in markers of inflammation, endothe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436eb6b3f442f8f6a33d3e5714bfd96e
http://hdl.handle.net/11391/1480493

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Patients with primary antiphospholipid antibody syndrome and without associated vascular risk factors present a normal endothelial function

Autor: Maria Cristina Vedovati, Stefania Momi, A. M. Mezzasoma, Elisa Boscaro, Rino Migliacci, Cecilia Becattini, Amelia Ruffatti, Monica Facco, Giuseppe Guglielmini, Vittorio Pengo, Paolo Gresele

Introduction Primary antiphospholipid antibody syndrome (PAPS) is characterized by venous or arterial thrombosis and positive antiphospholipid antibodies. It is controversial whether PAPS patients have early atherosclerosis. Endothelial dysfunction i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e51d65b1e10e95761d30738290220957
http://hdl.handle.net/11577/2514797

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A new case of acquired Glanzmann's thrombasthenia: Diagnostic value of flow cytometry

Autor: Silvia Giannini, Roberta Rossi, Paolo Gresele, Giuseppe Guglielmini, A. M. Mezzasoma, Emanuela Falcinelli

Background: Acquired Glanzmann's thrombasthenia (aGT) is a rare hemorrhagic disorder caused by autoantibodies, alloantibodies, or paraproteins directed against platelet GPIIb/IIIa. Its diagnosis requires several laboratory assays and mixing tests, wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621035e559693e2576dc9c53c8488655
http://hdl.handle.net/11391/119364

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NCX4016: a novel antithrombotic agent

Autor: Paolo Gresele, Stefania Momi, A. M. Mezzasoma

Despite great advantages in antithrombotic treatments, important limitations of the presently available drugs encourage the search of more effective agents. Within the cardiovascular system, nitric oxide exerts several activities which may have an an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a83b6304d6ff7007490869cdeab122
http://hdl.handle.net/11391/164518

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Prevention of pulmonary thromboembolism by NCX 4016, a nitric oxide-releasing aspirin

Autor: William E. Paul, Mario Leone, Clive P. Page, Michael Emerson, P Del Soldato, Paolo Gresele, A. M. Mezzasoma, Stefania Momi

Publikováno v: European journal of pharmacology. 397(1)

We studied the antithrombotic activity of 2-acetoxybenzoate 2-[1-nitroxy-methyl]-phenyl ester (NCX 4016), a novel nitric oxide (NO)-releasing aspirin derivative, in vivo in different animal models of platelet-dependent and independent pulmonary throm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c3e3dbb857dcf3dc799f4ec171aa28
https://pubmed.ncbi.nlm.nih.gov/10844112

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5-ASA-glutamate protects rats from inflammatory bowel disease induced by intracolonic administration of trinitrobenzensulfonic acid

Autor: C, Clerici, G, Gentili, R, Pellicciari, P, Gresele, A M, Mezzasoma, M, Giansanti, M, Clementi, G, Bartoli, S, Balò, R, Modesto, A G, Aburbeh, O, Morelli, A, Morelli

Publikováno v: Italian journal of gastroenterology and hepatology. 30(4)

A new amino acid derivative of 5-aminosalicylic acid, 5-ASA-glutamate, releases 5-aminosalicylic acid independently of the action of bacterial azoreductases or adapt intestinal pH. In this study, 5-ASA-glutamate was compared with sulphasalazine with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c681a69196000200fc8ad7a554325dd6
https://pubmed.ncbi.nlm.nih.gov/9789134

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PAF levels in saliva are regulated by inflammatory cells

Autor: E. Ribaldi, N. Staffolani, Gianfrancesco Goracci, Paolo Gresele, M. Guerra, A. M. Mezzasoma

Platelet activating factor (PAF), a powerful inflammatory phospholipid mediator, has been detected in normal human saliva and found to be increased in periodontitis. The cellular source of PAF in saliva is controversial although several data suggest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c502b42378631ac2fba37703a7de3d
http://hdl.handle.net/11391/906100

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