Zobrazeno 1 - 10
of 2 397
pro vyhledávání: '"A M, Lutz"'
Autor:
Georg Hahn, Sharon M. Lutz, Julian Hecker, Dmitry Prokopenko, Michael H. Cho, Edwin K. Silverman, Scott T. Weiss, Christoph Lange
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-20 (2024)
Abstract The computation of a similarity measure for genomic data is a standard tool in computational genetics. The principal components of such matrices are routinely used to correct for biases due to confounding by population stratification, for in
Externí odkaz:
https://doaj.org/article/9e85b3a4726d4c48be715654b1c4bd13
Autor:
Ahmed Edris, Kirsten Voorhies, Sharon M. Lutz, Carlos Iribarren, Ian Hall, Ann Chen Wu, Martin Tobin, Katherine Fawcett, Lies Lahousse
Publikováno v:
ERJ Open Research, Vol 10, Iss 1 (2024)
Background Asthma exacerbations reflect disease severity, affect morbidity and mortality, and may lead to declining lung function. Inflammatory endotypes (e.g. T2-high (eosinophilic)) may play a key role in asthma exacerbations. We aimed to assess wh
Externí odkaz:
https://doaj.org/article/e58f8eefa83b4c4393c364d85f85daa2
Autor:
Kirsten Voorhies, Kendra Young, Fang-Chi Hsu, Nicholette D. Palmer, Merry-Lynn N. McDonald, Sanghun Lee, Georg Hahn, Julian Hecker, Dmitry Prokopenko, Ann Chen Wu, Elizabeth A. Regan, Dawn DeMeo, Greg L. Kinney, James D. Crapo, Michael H. Cho, Edwin K. Silverman, Christoph Lange, Matthew J. Budoff, John E. Hokanson, Sharon M. Lutz
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 11, Iss 7, p 194 (2024)
Background: Coronary artery calcium (CAC) is a marker of subclinical atherosclerosis and is a complex heritable trait with both genetic and environmental risk factors, including sex and smoking. Methods: We performed genome-wide association (GWA) ana
Externí odkaz:
https://doaj.org/article/0abf222a64e34bfb919a8d586d67f502
Autor:
Kirsten Voorhies, Julian Hecker, Sanghun Lee, Georg Hahn, Dmitry Prokopenko, Merry-Lynn McDonald, Alexander C. Wu, Ann Wu, John E. Hokanson, Michael H. Cho, Christoph Lange, Karin F. Hoth, Sharon M. Lutz
Publikováno v:
Genes, Vol 15, Iss 5, p 565 (2024)
Depression is heritable, differs by sex, and has environmental risk factors such as cigarette smoking. However, the effect of single nucleotide polymorphisms (SNPs) on depression through cigarette smoking and the role of sex is unclear. In order to e
Externí odkaz:
https://doaj.org/article/785141f62f5a4526b8470752e61f14e6
Autor:
Amélie Taschereau, Kathrine Thibeault, Catherine Allard, Diana Juvinao-Quintero, Patrice Perron, Sharon M. Lutz, Luigi Bouchard, Marie-France Hivert
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background In utero exposure to maternal hyperglycemia has been associated with an increased risk for the development of chronic diseases in later life. These predispositions may be programmed by fetal DNA methylation (DNAm) changes that per
Externí odkaz:
https://doaj.org/article/5df9f8d6d96c4fcaa68d8dd26b3c6c69
Publikováno v:
European Physical Journal C: Particles and Fields, Vol 83, Iss 5, Pp 1-14 (2023)
Abstract We perform an analysis of Lattice QCD data on baryon octet and decuplet masses based on the chiral SU(3) Lagrangian. Low-energy constants (LEC) are adjusted to describe baryon masses from a large set of CLS ensembles, where finite-box and di
Externí odkaz:
https://doaj.org/article/08dc25155a6b475e917466989fdee8c4
Autor:
Julian Hecker, Sanghun Lee, Priyadarshini Kachroo, Dmitry Prokopenko, Anna Maaser-Hecker, Sharon M. Lutz, Georg Hahn, Rafael Irizarry, Scott T. Weiss, Dawn L. DeMeo, Christoph Lange
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
ABSTRACTBackground: Recent studies have identified thousands of associations between DNA methylation CpGs and complex diseases/traits, emphasizing the critical role of epigenetics in understanding disease aetiology and identifying biomarkers. However
Externí odkaz:
https://doaj.org/article/ca2e6b037851433db0d38b74bde03ccd
Autor:
Brigitta M. Lutz, Klaus-Dieter Schaser, Jurgen Weitz, Johanna Kirchberg, Hagen Fritzsche, Alexander C. Disch, Albert Busch, Steffen Wolk, Christian Reeps
Publikováno v:
Current Oncology, Vol 30, Iss 3, Pp 2555-2568 (2023)
Malignancies with an extended encasement or infiltration of the aorta were previously considered inoperable. This series demonstrates replacement and subsequent resection of the thoracoabdominal aorta and its large branches as an adjunct to curative
Externí odkaz:
https://doaj.org/article/ed4395f2b890414998123b4c7881f0d4
Autor:
Cody A. Keller, Shaya Zarkesh, Jianhua Zhou, Amelie M. Lutz, Dimitre Hristov, Aya Kamaya, Ahmed El Kaffas
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Quantitative three-dimensional molecular ultrasound is a promising technology for longitudinal imaging applications such as therapy monitoring; the risk profile is favorable compared to positron emission tomography and computed tomography. H
Externí odkaz:
https://doaj.org/article/9a6cb1f1089a44f2a5e952259be1305b
Autor:
Kirsten Voorhies, Akram Mohammed, Lokesh Chinthala, Sek Won Kong, In-Hee Lee, Alvin T. Kho, Michael McGeachie, Kenneth D. Mandl, Benjamin Raby, Melanie Hayes, Robert L. Davis, Ann Chen Wu, Sharon M. Lutz
Publikováno v:
Genes, Vol 15, Iss 4, p 420 (2024)
Inhaled corticosteroids (ICS) are efficacious in the treatment of asthma, which affects more than 300 million people in the world. While genome-wide association studies have identified genes involved in differential treatment responses to ICS in asth
Externí odkaz:
https://doaj.org/article/57690ce26e424277bd9abde8564f2ad0