Zobrazeno 1 - 10
of 39
pro vyhledávání: '"A M, Kritsyn"'
Autor:
A. M. Kritsyn, V. V. Komissarov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 44:705-711
A novel approach to the synthesis of α-amino-ω-nucleo carboxylic acids, analogs of willardiin, an activator of the receptor of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid, which is responsible for the transfer of a fast stimulating signa
Autor:
V. L. Tunitskaya, Sergey N. Kochetkov, V. V. Komissarov, Vladimir A. Mitkevich, A. V. Mukovnya, A. M. Kritsyn
Publikováno v:
Molecular Biology. 44:931-938
Nonstructural protein 3 (NS3) of hepatitis C virus plays a key role in the functioning of the virus. NS3 displays three enzymatic activities, namely, protease activity associated with the N-terminal domain, coupled nucleoside triphosphotase (NTPase),
[The interaction of NS3 protein of hepatitis C virus with polymethylen derivatives of nucleic bases]
Autor:
A V, Mukovnia, V V, Komissarov, A M, Kritsyn, V A, Mit'kevich, V L, Tunitskaia, S N, Kochetkov
Publikováno v:
Molekuliarnaia biologiia. 44(6)
NS3 protein of hepatitis C virus plays the key role in the virus functioning. It possesses three enzymatic activities, namely protease activity, associated with N-terminal domain of the protein, and helicase/NTPase activities specific for C-terminal
Publikováno v:
Bioorganicheskaia khimiia. 34(1)
New polymethylene derivatives of nucleic bases with beta-diketo function in omega-position were prepared by alkylation of uracil, thymine, and cytosine. Their physicochemical properties and effect on the E. coli uridine phosphorylase were studied.
Autor:
A M, Kritsyn, V V, Komissarov
Publikováno v:
Bioorganicheskaia khimiia. 31(6)
New polymethylene derivatives of nucleic bases containing a keto function in the omega-position were synthesized by alkylation of nucleic bases with 2-(3-chloropropyl)-2-phenyl-1,3-dioxolane and the subsequent deblocking of the keto group; their phys
Autor:
A M, Kritsyn, V V, Komissarov
Publikováno v:
Bioorganicheskaia khimiia. 30(5)
New polymethylene derivatives of nucleic bases containing a beta-dioxo function at the omega-position were synthesized by alkylation of uracil, thymine, and cytosine with 1-(7-chloroheptanoyl)cyclohexan-2-one, and their physicochemical properties wer
Autor:
N A, Grigorenko, J, Vepsalainen, A, Jarvinen, T A, Keinanen, L, Alhonen, J, Janne, A M, Kritsyn, A R, Khomutov
Publikováno v:
Bioorganicheskaia khimiia. 30(4)
A five-step synthesis of alpha-methylspermidine (1,8-diamino-5-azanonane), the first polyamine analogue preventing pathological consequences of spermidine depletion in transgenic rats overproducing spermine/spermidine N'-acetyltransferase, from ethyl
Publikováno v:
Bioorganicheskaia khimiia. 27(3)
N9-Polymethylene derivatives of adenine and hypoxanthine with various functional groups in the omega-position of the alkyl substituent were synthesized. Their physico-chemical properties and effect on the HIV reverse transcriptase and DNA topoisomera
Publikováno v:
Bioorganicheskaia khimiia. 26(10)
N1-Acyclic derivatives of pyrimidine bases (uracil, thymine, and cytosine) with hydrophobic polymethylene chains containing various functional groups in an omega-position of the alkyl substituent were synthesized. Their physicochemical properties and
Publikováno v:
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 25:384-387