Zobrazeno 1 - 10
of 132
pro vyhledávání: '"A M, Krichevsky"'
Autor:
Lien D. Nguyen, Zhiyun Wei, M. Catarina Silva, Sergio Barberán-Soler, Jiarui Zhang, Rosalia Rabinovsky, Christina R. Muratore, Jonathan M. S. Stricker, Colin Hortman, Tracy L. Young-Pearse, Stephen J. Haggarty, Anna M. Krichevsky
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract MicroRNAs (miRNAs) regulate fundamental biological processes by silencing mRNA targets and are dysregulated in many diseases. Therefore, miRNA replacement or inhibition can be harnessed as potential therapeutics. However, existing strategies
Externí odkaz:
https://doaj.org/article/b8a8e54f65f640bfad7b904c07567fde
Autor:
Mikhail I. Kremenetskiy, Vladimir M. Krichevsky, Viktoria V. Solovieva, Anastasia N. Nikonorova
Publikováno v:
Georesursy, Vol 25, Iss 3, Pp 151-162 (2023)
A technique for monitoring of a production well rate dynamics based on the results of long-term temperature measurements in the wellbore at a certain depth which is significantly higher than the productive formation in real time is presented. The pro
Externí odkaz:
https://doaj.org/article/d79322af8adb4e3f8b97f2c01d759f0b
Autor:
Yanhong Zhang, Rosalia Rabinovsky, Zhiyun Wei, Rachid El Fatimy, Evgeny Deforzh, Bai Luan, Leonid Peshkin, Erik J. Uhlmann, Anna M. Krichevsky
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 265-275 (2023)
MicroRNA-10b (miR-10b) is an essential glioma driver and one of the top candidates for targeted therapies for glioblastoma and other cancers. This unique miRNA controls glioma cell cycle and viability via an array of established conventional and unco
Externí odkaz:
https://doaj.org/article/10a4b48db9e44e428e91f68ba2b1e1e6
Publikováno v:
Cells, Vol 12, Iss 22, p 2660 (2023)
While it is well known that 98–99% of the human genome does not encode proteins, but are nevertheless transcriptionally active and give rise to a broad spectrum of noncoding RNAs [ncRNAs] with complex regulatory and structural functions, specific f
Externí odkaz:
https://doaj.org/article/ae6768801d8545108bcafe6cbe0c9d95
Autor:
Rachid El Fatimy, Yanhong Zhang, Evgeny Deforzh, Mahalakshmi Ramadas, Harini Saravanan, Zhiyun Wei, Rosalia Rabinovsky, Nadiya M. Teplyuk, Erik J. Uhlmann, Anna M. Krichevsky
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-19 (2022)
Abstract Background miRNAs are regulatory transcripts established as repressors of mRNA stability and translation that have been functionally implicated in carcinogenesis. miR-10b is one of the key onco-miRs associated with multiple forms of cancer.
Externí odkaz:
https://doaj.org/article/f937b4f91e9b476aa787c3a706e91a6a
Autor:
Daria O. Ignatyeva, Dolendra Karki, Andrey A. Voronov, Mikhail A. Kozhaev, Denis M. Krichevsky, Alexander I. Chernov, Miguel Levy, Vladimir I. Belotelov
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
The authors fabricate and investigate the metasurface made of 2D iron-garnet subwavelength nanopillar array on a thin iron-garnet film. It exhibits high quality-factor resonances, leading to a multifold increase in light intensity modulation of the t
Externí odkaz:
https://doaj.org/article/d0fce897b2a742ffb2d782027705295c
Autor:
Erik J. Uhlmann, Charles E. Mackel, Evgeny Deforzh, Rosalia Rabinovsky, Priscilla K. Brastianos, Hemant Varma, Rafael A. Vega, Anna M. Krichevsky
Publikováno v:
Journal of Neuro-Oncology. 162:109-118
Purpose Meningioma is the most common primary central nervous system tumor often causing serious complications, and presently no medical treatment is available. The goal of this study was to discover miRNAs dysregulated in meningioma, and explore miR
Publikováno v:
Genes, Vol 12, Iss 12, p 2005 (2021)
Despite the enormous burden of Alzheimer’s disease and related dementias (ADRD) on patients, caregivers, and society, only a few treatments with limited efficacy are currently available. While drug development conventionally focuses on disease-asso
Externí odkaz:
https://doaj.org/article/d950e9fdffe64819870447d708e479ea
Autor:
Ailiang Zeng, Zhiyun Wei, Rosalia Rabinovsky, Hyun Jung Jun, Rachid El Fatimy, Evgeny Deforzh, Ramil Arora, Yizheng Yao, Shun Yao, Wei Yan, Erik J. Uhlmann, Alain Charest, Yongping You, Anna M. Krichevsky
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101420- (2020)
Summary: Glioblastoma (GBM) may arise from astrocytes through a multistep process involving a progressive accumulation of mutations. We explored whether GBM-derived extracellular vesicles (EVs) may facilitate neoplastic transformation and malignant g
Externí odkaz:
https://doaj.org/article/affd28779865474595993f92557b0b03
Autor:
Zhiyun Wei, Xingjun Meng, Rachid El Fatimy, Bowen Sun, Dongmei Mai, Junfang Zhang, Ramil Arora, Ailiang Zeng, Pingyi Xu, Shaogang Qu, Anna M. Krichevsky, Dennis J. Selkoe, Shaomin Li
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
As the most common cause of progressive cognitive decline in humans, Alzheimer's disease (AD) has been intensively studied, but the mechanisms underlying its profound synaptic dysfunction remain unclear. Here we confirm that exposing wild-type mice t
Externí odkaz:
https://doaj.org/article/0555bcd7882b4d0fb94610581f5138af