Zobrazeno 1 - 10
of 43
pro vyhledávání: '"A M, Ishov"'
Autor:
Sadia Sarwar, Viacheslav M. Morozov, Mallory A. Newcomb, Bowen Yan, Jason O. Brant, Rene Opavsky, Olga A. Guryanova, Alexander M. Ishov
Publikováno v:
Cell Death and Disease, Vol 15, Iss 8, Pp 1-12 (2024)
Abstract Prostate cancer (PCa) is the second leading cause of cancer-related death in American men. PCa that relapses after hormonal therapies, referred to as castration resistant PCa (CRPC), often presents with metastases (mCRPC) that are the major
Externí odkaz:
https://doaj.org/article/36426723b04b45b785326e5d2af944fe
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-10 (2022)
Abstract Androgen ablation therapy is the standard of care for newly diagnosed prostate cancer (PC) patients. PC that relapsed after hormonal therapy, referred to as castration-resistant PC (CRPC), often presents with metastasis (mCRPC) and is the ma
Externí odkaz:
https://doaj.org/article/1b8c9d615a904ea196a9b4a811bdfb93
Publikováno v:
Epigenetics & Chromatin, Vol 10, Iss 1, Pp 1-18 (2017)
Abstract Background The main chromatin unit, the nucleosome, can be modulated by the incorporation of histone variants that, in combination with posttranslational histones modifications, determine epigenetics properties of chromatin. Understanding th
Externí odkaz:
https://doaj.org/article/bdf67d891fd549d1bfaf9b7f4f601aac
Autor:
Viacheslav M. Morozov, Alberto Riva, Sadia Sarwar, WanJu Kim, Jianping Li, Lei Zhou, Jonathan D. Licht, Yehia Daaka, Alexander M. Ishov
Publikováno v:
bioRxiv
Incorporation of histone variant H3.3 comprises active territories of chromatin. Exploring the function of H3.3 in prostate cancer (PC), we found that knockout (KO) of H3.3 chaperone HIRA suppresses PC growthin vitroand in xenograft settings, deregul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312423df6a7718ddb04ed409e2f27021
https://europepmc.org/articles/PMC10197601/
https://europepmc.org/articles/PMC10197601/
Autor:
Lu Li, Pamela Chamales, Jared R. Stees, Mingyi Xie, Paul C. Wassel, Marissa Brackett, David T. Y. Yu, Jörg Bungert, Ekaterina Gavrilova, Aishwarya Gurumurthy, Daniel Stribling, Jinyang Chen, Alexander M. Ishov
Publikováno v:
Nucleic Acids Research
Super-enhancers (SEs) mediate high transcription levels of target genes. Previous studies have shown that SEs recruit transcription complexes and generate enhancer RNAs (eRNAs). We characterized transcription at the human and murine β-globin locus c
Publikováno v:
Emerging Topics in Life Sciences
Genes under control of super-enhancers are expressed at extremely high levels and are frequently associated with nuclear speckles. Recent data suggest that the high concentration of unphosphorylated RNA polymerase II (Pol II) and Mediator recruited t
Publikováno v:
Epigenetics & Chromatin, Vol 10, Iss 1, Pp 1-18 (2017)
Epigenetics & Chromatin
Epigenetics & Chromatin
Background The main chromatin unit, the nucleosome, can be modulated by the incorporation of histone variants that, in combination with posttranslational histones modifications, determine epigenetics properties of chromatin. Understanding the mechani
Publikováno v:
Oncotarget
// Viacheslav M. Morozov 1 , Ying Li 1, 3 , Matthew M. Clowers 2 and Alexander M. Ishov 1 1 Department of Anatomy and Cell Biology and Health Cancer Center, University of Florida College of Medicine, Gainesville, FL 32610, USA 2 Department of Cellula
Autor:
Angelie Rivera-Rodriguez, Carlos Rinaldi, Alexander M. Ishov, Viacheslav M. Morozov, Andreina Chiu-Lam
Publikováno v:
International Journal of Nanomedicine
Angelie Rivera-Rodriguez,1 Andreina Chiu-Lam,2 Viacheslav M Morozov,3,4 Alexander M Ishov,3,4 Carlos Rinaldi1,2,4 1J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA; 2Department of Chemical Eng
Autor:
Alexander M. Ishov, Serena Giovinazzi, Pietro Sirleto, Viacheslav M. Morozov, Vasilisa Aksenova, Roberto T. Zori, William C. Reinhold
Publikováno v:
Oncotarget
// Serena Giovinazzi 1,2 , Pietro Sirleto 3 , Vasilisa Aksenova 4 , Viacheslav M. Morozov 1,2 , Roberto Zori 5 , William C. Reinhold 6 and Alexander M. Ishov 1,2 1 Department of Anatomy and Cell Biology, University of Florida College of Medicine, Gai