Zobrazeno 1 - 10
of 56
pro vyhledávání: '"A M, Goorin"'
Autor:
Steven E. Lipshultz, Allen M. Goorin, Judith K. Sato, Laurel J. Steinherz, Cindy L. Schwartz, Mark L. Bernstein, Holcombe E. Grier, Lisa A. Teot, Paul A. Meyers, Mark Krailo, Mark C. Gebhardt, Leonard H. Wexler, Meenakshi Devidas, John H. Healey
Publikováno v:
Pediatric Blood & Cancer. 63:54-61
Background Although chemotherapy has improved outcome of osteosarcoma, 30–40% of patients succumb to this disease. Survivors experience substantial morbidity and mortality from anthracycline-induced cardiotoxicity. We hypothesized that the cardiopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14e32ff5353c72f1b711fce324476317
https://doi.org/10.1002/pbc.25753
https://doi.org/10.1002/pbc.25753
Autor:
Leonard H. Wexler, Cindy L. Schwartz, Allen M. Goorin, Richard Gorlick, Jeffrey A. Toretsky, Mark L. Bernstein, Donald A. Barkauskas, Scott C. Borinstein, Mark Krailo
Publikováno v:
Pediatric Blood & Cancer. 61:749-752
To investigate the role of insulin-like growth factor-1 (IGF-1), in localized osteosarcoma, serum levels of IGF-1, IGFBP-2, and IGFBP-3 were measured in 224 similarly treated, newly diagnosed patients. We demonstrated that younger patients had lower
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30cf6494cd1334bc865590a10054ac2f
https://doi.org/10.1002/pbc.24778
https://doi.org/10.1002/pbc.24778
Autor:
David H. Ebb, Allen M. Goorin, Peter Beardsley, George Douglas Letson, Donald A. Barkauskas, Paul A. Meyers, Karen J. Marcus, Steven E. Lipshultz, Meenakshi Devidas, Neyssa Marina, William S. Ferguson, Mark Krailo, Gene P. Siegal, Mark L. Bernstein, Richard Gorlick, Holcombe E. Grier
Publikováno v:
Journal of Clinical Oncology. 30:2545-2551
Purpose Despite efforts to intensify chemotherapy, survival for patients with metastatic osteosarcoma remains poor. Overexpression of human epidermal growth factor receptor 2 (HER2) in osteosarcoma has been shown to predict poor therapeutic response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9921083cdd9d4bda578d32e26a421e13
https://doi.org/10.1200/jco.2011.37.4546
https://doi.org/10.1200/jco.2011.37.4546
Autor:
Darryl C. Grendahl, Nadya V. Koshkina, Allen M. Goorin, Carola A.S. Arndt, Martin L. Blakely, Mark L. Bernstein, Mark Krailo, Carrie Y. Inwards, Sharon A. Bell, Peter M. Anderson, Douglas S. Hawkins, Doojduen Villaluna, Neyssa Marina, Kaylee Ray, Eugenie S. Kleinerman
Publikováno v:
Clinical Cancer Research. 16:4024-4030
Purpose: Osteosarcoma most commonly recurs in the lung. Based on preliminary data on the antitumor effects of granulocyte-macrophage colony stimulating factor (GM-CSF) in animal models, and promising phase I trials, we embarked on a feasibility study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6c2c11aea4dd26171e15fa40af4a3c
https://doi.org/10.1158/1078-0432.ccr-10-0662
https://doi.org/10.1158/1078-0432.ccr-10-0662
Autor:
Cindy L. Schwartz, Paul A. Meyers, Allen M. Goorin, Mark L. Bernstein, Zhengjia Chen, Lisa A. Teot, Mark Krailo, Richard Gorlick, Holcombe E. Grier
Publikováno v:
Journal of Clinical Oncology. 25:2057-2062
Purpose Multiple drug resistance due to P-glycoprotein (P-gp) expression has been reported to be a cause of disease recurrence in osteosarcoma. Tumor specimens derived from children and young adults with osteosarcoma enrolled onto a national Intergro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28084be0140bc6307c72f2edbf26eb83
https://doi.org/10.1200/jco.2006.07.7776
https://doi.org/10.1200/jco.2006.07.7776
Autor:
Cindy L, Schwartz, Leonard H, Wexler, Mark D, Krailo, Lisa A, Teot, Meenakshi, Devidas, Laurel J, Steinherz, Allen M, Goorin, Mark C, Gebhardt, John H, Healey, Judith K, Sato, Paul A, Meyers, Holcombe E, Grier, Mark L, Bernstein, Steven E, Lipshultz
Publikováno v:
Pediatric bloodcancer. 63(1)
Although chemotherapy has improved outcome of osteosarcoma, 30-40% of patients succumb to this disease. Survivors experience substantial morbidity and mortality from anthracycline-induced cardiotoxicity. We hypothesized that the cardioprotectant dexr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a5a5fd3481f6b97f32a4bcef7f6d5a3
https://pubmed.ncbi.nlm.nih.gov/26398490
https://pubmed.ncbi.nlm.nih.gov/26398490
Autor:
Judith K. Sato, Cindy L. Schwartz, Donna L. Betcher, Andrew G. Huvos, Michael P. Link, Robert J. Wells, Mark L. Bernstein, John H. Healey, Michael Nieder, Mark Krailo, Allen M. Goorin, Joseph Montebello, William S. Ferguson, Richard B. Womer, Ernest U. Conrad, Paul A. Meyers, Gene P. Siegal, Lester E. Wold, Holcombe E. Grier, Michael E. Harris, Helen Nadel, Eugenie S. Kleinerman, Michael Weiner, Mark C. Gebhardt
Publikováno v:
Journal of Clinical Oncology. 23:2004-2011
Purpose To determine whether the addition of ifosfamide and/or muramyl tripeptide (MTP) encapsulated in liposomes to cisplatin, doxorubicin, and high-dose methotrexate (HDMTX) could improve the probability for event-free survival (EFS) in newly diagn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9868eeea2f2106567de565e340159d1
https://doi.org/10.1200/jco.2005.06.031
https://doi.org/10.1200/jco.2005.06.031
Autor:
Caroline Laverdiere, Ana Ruiz-Casado, Jose Jimeno, Andrew G. Huvos, Allen M. Goorin, Leonard Wexler, Richard Gorlick, George D. Demetri, Robert G. Maki, Jeffrey G. Supko, David Harmon, E. Anders Kolb, Paul A. Meyers, Cecilia Guzman, John H. Healey, Rochelle Bagatell
Publikováno v:
Cancer. 98:832-840
BACKGROUND Recurrent osteosarcoma is a drug-resistant disease with a dismal prognosis. The objective of this Phase II study was to evaluate the activity of ecteinascidin 743 (ET-743) as a salvage therapy in these patients. METHODS Patients with recur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5b398d1429fd11d415fffb8a0de68f
https://doi.org/10.1002/cncr.11563
https://doi.org/10.1002/cncr.11563
Autor:
Michael E. Harris, Lee J. Helman, Holcombe E. Grier, Meenakshi Devidas, Mark C. Gebhardt, Michael P. Link, Alberto G. Ayala, Allen M. Goorin, Douglas J. Schwartzentruber
Publikováno v:
Journal of Clinical Oncology. 21:1574-1580
Purpose: Successful therapeutic interventions to prevent disease progression in patients with nonmetastatic osteosarcoma have included surgery with adjuvant chemotherapy. Presurgical chemotherapy has been advocated for these patients because of putat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c0e5c51d60a0a484c40ae0267a3b12b
https://doi.org/10.1200/jco.2003.08.165
https://doi.org/10.1200/jco.2003.08.165
Autor:
Allen M, Goorin, Michael B, Harris, Mark, Bernstein, William, Ferguson, Meenakshi, Devidas, Gene P, Siegal, Mark C, Gebhardt, Cindy L, Schwartz, Michael, Link, Holcombe E, Grier
Publikováno v:
Journal of Clinical Oncology. 20:426-433
PURPOSE: The objectives of this trial were to estimate the response rate, progression-free survival, and overall survival of patients who received therapy with etoposide and high-dose ifosfamide, and to define the toxicity of this combination when pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d400cb5aa20cb2c38d19aa4389f1b5
https://doi.org/10.1200/jco.2002.20.2.426
https://doi.org/10.1200/jco.2002.20.2.426