Zobrazeno 1 - 10 of 64 pro vyhledávání: '"A M, Gillum"'
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ON 01910.Na (rigosertib) inhibits PI3K/Akt pathway and activates oxidative stress signals in head and neck cancer cell lines
Autor: Nagina Khudaynazar, Anil Prasad, Benjamin S. Hoffman, Ramana V. Tantravahi, Amanda M. Gillum
Publikováno v: Oncotarget
// Anil Prasad 1 , Nagina Khudaynazar 1 , Ramana V. Tantravahi 2 , Amanda M. Gillum 2 , Benjamin S. Hoffman 2 1 Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA 2 Onconova Therapeu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d473c827f65b18fb1f727de555ed5b72
https://doi.org/10.18632/oncotarget.12692
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6
Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies
Autor: Wood, A.M. Kaptoge, S. Butterworth, A.S. Willeit, P. Warnakula, S. Bolton, T. Paige, E. Paul, D.S. Sweeting, M. Burgess, S. Bell, S. Astle, W. Stevens, D. Koulman, A. Selmer, R.M. Verschuren, W.M.M. Sato, S. Njølstad, I. Woodward, M. Salomaa, V. Nordestgaard, B.G. Yeap, B.B. Fletcher, A. Melander, O. Kuller, L.H. Balkau, B. Marmot, M. Koenig, W. Casiglia, E. Cooper, C. Arndt, V. Franco, O.H. Wennberg, P. Gallacher, J. de la Cámara, A.G. Völzke, H. Dahm, C.C. Dale, C.E. Bergmann, M.M. Crespo, C.J. van der Schouw, Y.T. Kaaks, R. Simons, L.A. Lagiou, P. Schoufour, J.D. Boer, J.M.A. Key, T.J. Rodriguez, B. Moreno-Iribas, C. Davidson, K.W. Taylor, J.O. Sacerdote, C. Wallace, R.B. Quiros, J.R. Tumino, R. Blazer, D.G., II Linneberg, A. Daimon, M. Panico, S. Howard, B. Skeie, G. Strandberg, T. Weiderpass, E. Psaty, B.M. Kromhout, D. Salamanca-Fernandez, E. Kiechl, S. Krumholz, H.M. Grioni, S. Palli, D. Huerta, J.M. Price, J. Sundström, J. Arriola, L. Arima, H. Travis, R.C. Panagiotakos, D.B. Karakatsani, A. Trichopoulou, A. Kühn, T. Grobbee, D.E. Barrett-Connor, E. van Schoor, N. Boeing, H. Overvad, K. Kauhanen, J. Wareham, N. Langenberg, C. Forouhi, N. Wennberg, M. Després, J.-P. Cushman, M. Cooper, J.A. Rodriguez, C.J. Sakurai, M. Shaw, J.E. Knuiman, M. Voortman, T. Meisinger, C. Tjønneland, A. Brenner, H. Palmieri, L. Dallongeville, J. Brunner, E.J. Assmann, G. Trevisan, M. Gillum, R.F. Ford, I.F. Sattar, N. Lazo, M. Thompson, S.G. Ferrari, P. Leon, D.A. Davey Smith, G. Peto, R. Jackson, R. Banks, E. Di Angelantonio, E. Danesh, J. Veikko, S. Gómez de la Cámara, A. Rimm, E.B. Dallongeville, J.-P. Gillumn, R.F. Thompson, S. Emerging Risk Factors Collaboration/EPIC-CVD/UK Biobank Alcohol Study Group
Background: Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk for all-cause mortality and cardiovascular disease, we studied individual-partic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::83f5fb5767a07ea4e7751f49e119455c
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3107482
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Combined Administration of Rituximab and ON 013105 Induces Apoptosis in Mantle Cell Lymphoma Cells and Reduces Tumor Burden in a Mouse Model of Mantle Cell Lymphoma
Autor: Ramesh Kumar, M. V. Ramana Reddy, Ashutosh Shrivastava, E. Premkumar Reddy, Paula M. Kuzontkoski, Evangelos Papadopoulos, Anil Prasad, Amanda M. Gillum, Jerome E. Groopman
Publikováno v: Clinical Cancer Research. 19:85-95
Purpose: Mantle cell lymphoma (MCL) is an incurable B-cell lymphoma, and new therapeutic strategies are urgently needed. Experimental Design: The effects of ON 013105, a novel benzylstyryl sulfone kinase inhibitor, alone or with doxorubicin or rituxi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf8292cc148b023a7bd8cb2fdab48ea
https://doi.org/10.1158/1078-0432.ccr-12-1425
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Oblimersen Bcl-2 Antisense: Facilitating Apoptosis in Anticancer Treatment
Autor: Amanda M. Gillum, Richard J. Klasa, Stanley R. Frankel, Robert E. Klem
Publikováno v: Antisense and Nucleic Acid Drug Development. 12:193-213
The components of the apoptotic program are targets for anticancer therapy. Bcl-2 protein inhibits apoptosis and confers resistance to treatment with traditional cytotoxic chemotherapy, radiotherapy, and monoclonal antibodies (mAb). Oblimersen sodium
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125f768b161255dc5064e01d47400912
https://doi.org/10.1089/108729002760220798
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9
Antimycins, Inhibitors of ATP-Citrate Lyase, from a Streptomyces sp
Autor: Paul V. Kaplita, Vincent Marinelli, David M. Sedlock, Christopher C. Chadwick, Joseph J. Oleynek, Hao H. Sun, Colin J. Barrow, Raymond Cooper, Amanda M. Gillum
Publikováno v: The Journal of Antibiotics. 50:729-733
A related group of compounds belonging to the antimycin class of antibiotics was found in culture broth produced by a Streptomyces species. The group includes known antimycins A1, A2, A3 and A4, and new antimycins A7 and A8. These compounds inhibit A
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28d2c16edff5b5c0861550345a91f27
https://doi.org/10.7164/antibiotics.50.729
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10
A Metalloproteinase Inhibitor fromDoliocarpus verruculosus
Autor: Paul V. Kaplita, Mary B. Stawicki, David R. Houck, Robert C. Wahl, Hao H. Sun, Amanda M. Gillum, Raymond Cooper, Ruthann McGarry
Publikováno v: Phytotherapy Research. 10:194-197
In our natural products screening programme for the discovery of competitive inhibitors of the matrix metalloproteinases, stromelysin and collagenase, we have isolated an active compound, betulinic acid (1), from the plant Doliocarpus verruculosus. B
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f40adde39cdddb5a91a48cafa6edbfbc
https://doi.org/10.1002/(sici)1099-1573(199605)10:3<194::aid-ptr703>3.0.co
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