Zobrazeno 1 - 10
of 29
pro vyhledávání: '"A M, Ghoumari"'
Autor:
Charly Abi Ghanem, Cindy Degerny, Rashad Hussain, Philippe Liere, Antoine Pianos, Sophie Tourpin, René Habert, Wendy B Macklin, Michael Schumacher, Abdel M Ghoumari
Publikováno v:
PLoS Genetics, Vol 13, Iss 11, p e1007049 (2017)
The oligodendrocyte density is greater and myelin sheaths are thicker in the adult male mouse brain when compared with females. Here, we show that these sex differences emerge during the first 10 postnatal days, precisely at a stage when a late wave
Externí odkaz:
https://doaj.org/article/b3f9d8add9a544e1b6555ef21c92f5a8
Autor:
Antoine Pianos, Narender Kumar, Michael Schumacher, Martine El-Etr, Celine Boucher, Marion Rame, Abdel M. Ghoumari, Regine Sitruk-Ware, Philippe Liere
Publikováno v:
Glia. 63:104-117
Multiple Sclerosis affects mainly women and consists in intermittent or chronic damages to the myelin sheaths, focal inflammation, and axonal degeneration. Current therapies are limited to immunomodulators and antiinflammatory drugs, but there is no
Autor:
Abdel M. Ghoumari, Florencia Labombarda, Michael Schumacher, Rachida Guennoun, Regine Sitruk-Ware, Claudia Mattern, Jean-Paul Oudinet, Philippe Liere, A. F. De Nicola
Publikováno v:
Progress in Neurobiology. 113:6-39
Progesterone is commonly considered as a female reproductive hormone and is well-known for its role in pregnancy. It is less well appreciated that progesterone and its metabolite allopregnanolone are also male hormones, as they are produced in both s
Autor:
Etienne-Emile Baulieu, Claudia Mattern, Abdel M. Ghoumari, Elisabeth Traiffort, Sakina Mhaouty-Kodja, Robin J.M. Franklin, Charly Abi Ghanem, Kaja Smietanka, Sumaira Javaid, M. Said Ghandour, Bartosz Bielecki, Michael Schumacher
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2016, 113 (51), pp.14829-14834. ⟨10.1073/pnas.1614826113⟩
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (51), pp.14829-14834. ⟨10.1073/pnas.1614826113⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2016, 113 (51), pp.14829-14834. ⟨10.1073/pnas.1614826113⟩
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (51), pp.14829-14834. ⟨10.1073/pnas.1614826113⟩
International audience; Lost myelin can be replaced after injury or during demyelinating diseases in a regenerative process called remyelination. In the central nervous system (CNS), the myelin sheaths, which protect axons and allow the fast propagat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a46cbf581e61aa0dd837c4147758b316
https://zenodo.org/record/895974
https://zenodo.org/record/895974
Publikováno v:
Maturitas. 68:47-51
Multiple sclerosis (MS) is one of the most common neurological disorders. It affects mainly women. This autoimmune disease of the central nervous system (CNS) is characterized by intermittent or chronic damage to the myelin sheaths (demyelination), f
Autor:
Ghjuvan’Ghjacumu Shackleford, Eleni T. Tzavara, Michael Schumacher, Cyrille Deboux, Delphine Meffre, Abdel M. Ghoumari, Amalia Trousson, Brahim Nait Oumesmar, Philippe Liere, Victor Gorgievski, Julien Grenier, Charbel Massaad, Mehdi Hichor, Etienne-Emile Baulieu, Frédééric Charbonnier
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2015, 112 (24), pp.7587-7592. ⟨10.1073/pnas.1424951112⟩
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (24), pp.7587-7592. ⟨10.1073/pnas.1424951112⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2015, 112 (24), pp.7587-7592. ⟨10.1073/pnas.1424951112⟩
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (24), pp.7587-7592. ⟨10.1073/pnas.1424951112⟩
International audience; The identification of new pathways governing myelination provides innovative avenues for remyelination. Liver X receptors (LXRs) a and beta are nuclear receptors activated by oxysterols that originated from the oxidation of ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51dfcf04179935e1a4136b67861f988c
https://hal.archives-ouvertes.fr/hal-01542311
https://hal.archives-ouvertes.fr/hal-01542311
Autor:
Abdel M. Ghoumari, Céline Tomkiewicz, Carole Levenes, Etienne-Emile Baulieu, Claire Piochon, Isabelle Dusart, Bernard Eychenne, Michael Schumacher
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2006, 20 (9), pp.1377-1386. ⟨10.1096/fj.05-5832com⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2006, 20 (9), pp.1377-1386. ⟨10.1096/fj.05-5832com⟩
International audience; In several regions of the developing nervous system, neurons undergo programmed cell death. In the rat cerebellum, Purkinje cell apoptosis is exacerbated when cerebellar slices are cultured during the first postnatal week. To
Publikováno v:
Neuroscience. 135:47-58
We have previously demonstrated that progesterone significantly increases the rate of myelination in organotypic slice cultures of 7-day-old rat and mouse cerebellum. Here, we show that progesterone (20microM) stimulates the proliferation of oligoden
Autor:
B. W. O'Malley, Abdel M. Ghoumari, Etienne-Emile Baulieu, Philippe Leclerc, Michael Schumacher, Bernard Eychenne, C. Ibanez, Martine El-Etr
Publikováno v:
Journal of Neurochemistry. 86:848-859
We have previously shown that progesterone (PROG) is synthesized by Schwann cells and promotes myelin formation in the peripheral nervous system (PNS). We now report that this neurosteroid also stimulates myelination in organotypic slice cultures of
Autor:
Martine, El-Etr, Marion, Rame, Celine, Boucher, Abdel M, Ghoumari, Narender, Kumar, Philippe, Liere, Antoine, Pianos, Michael, Schumacher, Regine, Sitruk-Ware
Publikováno v:
Glia. 63(1)
Multiple Sclerosis affects mainly women and consists in intermittent or chronic damages to the myelin sheaths, focal inflammation, and axonal degeneration. Current therapies are limited to immunomodulators and antiinflammatory drugs, but there is no