Zobrazeno 1 - 10
of 16
pro vyhledávání: '"A M, Dedman"'
Autor:
Philip M. Hopkins, Fanning Zeng, Alexandra M. Dedman, Carol J. Milligan, Alan N. Bateson, Yahya M Bahnasi, David J. Beech, H M Wright
Publikováno v:
British Journal of Pharmacology. 153:1505-1512
Background and purpose: TRPC5 is a mammalian homologue of the Drosophila Transient Receptor Potential (TRP) channel and has expression and functions in the cardiovascular and nervous systems. It forms a calcium-permeable cation channel that can be ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1be68f170ebb6d7a00d59fa1347e5fa
https://doi.org/10.1038/sj.bjp.0707689
https://doi.org/10.1038/sj.bjp.0707689
A Sphingosine-1–Phosphate-Activated Calcium Channel Controlling Vascular Smooth Muscle Cell Motility
Autor:
Alexandra M. Dedman, Alex Cheong, Damian McHugh, Samir S. Shah, Karen E. Porter, Katsuhiko Muraki, David J. Beech, Alan N. Bateson, Piruthivi Sukumar, Jacqueline Naylor, Jing Li, Fanning Zeng, Philippa K. Flemming, Shang-Zhong Xu, Christopher M. Munsch
Publikováno v:
Circulation Research. 98:1381-1389
In a screen of potential lipid regulators of transient receptor potential (TRP) channels, we identified sphingosine-1–phosphate (S1P) as an activator of TRPC5. We explored the relevance to vascular biology because S1P is a key cardiovascular signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d4d5c8dafed754033187cc2af34d5f
https://doi.org/10.1161/01.res.0000225284.36490.a2
https://doi.org/10.1161/01.res.0000225284.36490.a2
Autor:
Alexandra M. Dedman, Fanning Zeng, Shang-Zhong Xu, David J. Beech, Jing Li, Philippa K. Flemming, Jacqueline Naylor, Katsuhiko Muraki, Alan N. Bateson, Christopher D. Benham
Publikováno v:
Journal of Biological Chemistry. 281:4977-4982
TRPC calcium channels are emerging as a ubiquitous feature of vertebrate cells, but understanding of them is hampered by limited knowledge of the mechanisms of activation and identity of endogenous regulators. We have revealed that one of the TRPC ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e012568e03cc661169c98d72a8b240
https://doi.org/10.1074/jbc.m510301200
https://doi.org/10.1074/jbc.m510301200
Publikováno v:
Journal of Vascular Research. 39:122-130
We have previously shown expression of voltage-gated K+ channels (KV) in smooth muscle of cerebral arterioles and suggested the channels function to oppose voltage-dependent Ca2+ entry. However, other studies indicate that large conductance Ca2+-acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9abc8dfe868625f92f9512c964412dc2
https://doi.org/10.1159/000057761
https://doi.org/10.1159/000057761
Publikováno v:
The Journal of Physiology. 534:691-700
1. In this study we investigated the expression and function of the K(V)alpha1 subfamily of voltage-gated K(+) channels in terminal arterioles from rabbit cerebral circulation. 2. K(+) current was measured from smooth muscle cells within intact fresh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e94f2279673e32fe0ca14ce54de81af
https://doi.org/10.1111/j.1469-7793.2001.00691.x
https://doi.org/10.1111/j.1469-7793.2001.00691.x
Autor:
Hans-Martin Jäck, Yasser Majeed, Sarka Tumova, Alan N. Bateson, Alexandra M. Dedman, Bhaskar Kumar, Jürgen Wittmann, Karen E. Porter, Fanning Zeng, Christopher M. Munsch, David J. Beech
Publikováno v:
BMC Molecular Biology
BMC Molecular Biology, Vol 12, Iss 1, p 30 (2011)
BMC Molecular Biology, Vol 12, Iss 1, p 30 (2011)
Background Transient Receptor Potential Canonical 1 (TRPC1) is a widely-expressed mammalian cationic channel with functional effects that include stimulation of cardiovascular remodelling. The initial aim of this study was to investigate variation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c925f07d87ce2329a2485420bfbc7bb4
Publikováno v:
Cell Calcium
TRPC channels are a subset of the transient receptor potential (TRP) proteins widely expressed in mammalian cells. They are thought to be primarily involved in determining calcium or sodium entry and have broad-ranging functions that include regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dec93e340750731d6e48383e3b2d49
https://pubmed.ncbi.nlm.nih.gov/19324410
https://pubmed.ncbi.nlm.nih.gov/19324410
Autor:
Alexandra M. Dedman, Fanning Zeng, Alan N. Bateson, David J. Beech, Jaqueline Naylor, Yahya M Bahnasi
Publikováno v:
The FASEB Journal. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2961d1ef38aba7467961f233c73b250a
https://doi.org/10.1096/fasebj.20.5.lb18-c
https://doi.org/10.1096/fasebj.20.5.lb18-c
Autor:
Karen E. Porter, Alex Cheong, Samir S. Shah, Katsuhiko Muraki, Fanning Zeng, Christopher M. Munsch, David J. Beech, Alan N. Bateson, Jing Li, Alexandra M. Dedman, Philippa K. Flemming, Shang-Zhong Xu, Jacqueline Naylor
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c575446ff03761804fc69a9586142d7
https://doi.org/10.1096/fasebj.20.5.a1175-a
https://doi.org/10.1096/fasebj.20.5.a1175-a
Autor:
Shang-Zhong Xu, Katsuhiko Muraki, Philippa K. Flemming, Yahya M Bahnasi, Alan M Bateson, Alexandra M. Dedman, Fanning Zeng, David J. Beech
Publikováno v:
ResearcherID
Web of Science
Web of Science
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dbe13c7b51218616676bbb5dee6d773
https://doi.org/10.1096/fasebj.20.4.a330
https://doi.org/10.1096/fasebj.20.4.a330