Zobrazeno 1 - 10
of 36
pro vyhledávání: '"A M, DeMichele"'
Autor:
Julie E. Lang, Andres Forero-Torres, Douglas Yee, Christina Yau, Denise Wolf, John Park, Barbara A. Parker, A. Jo Chien, Anne M. Wallace, Rashmi Murthy, Kathy S. Albain, Erin D. Ellis, Heather Beckwith, Barbara B. Haley, Anthony D. Elias, Judy C. Boughey, Rachel L. Yung, Claudine Isaacs, Amy S. Clark, Hyo S. Han, Rita Nanda, Qamar J. Khan, Kristen K. Edmiston, Erica Stringer-Reasor, Elissa Price, Bonnie Joe, Minetta C. Liu, Lamorna Brown-Swigart, Emanuel F. Petricoin, Julia D. Wulfkuhle, Meredith Buxton, Julia L. Clennell, Ashish Sanil, Scott Berry, Smita M. Asare, Amy Wilson, Gillian L. Hirst, Ruby Singhrao, Adam L. Asare, Jeffrey B. Matthews, Michelle Melisko, Jane Perlmutter, Hope S. Rugo, W. Fraser Symmans, Laura J. van ‘t Veer, Nola M. Hylton, Angela M. DeMichele, Donald A. Berry, Laura J. Esserman
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract HSP90 inhibitors destabilize oncoproteins associated with cell cycle, angiogenesis, RAS-MAPK activity, histone modification, kinases and growth factors. We evaluated the HSP90-inhibitor ganetespib in combination with standard chemotherapy in
Externí odkaz:
https://doaj.org/article/f1ec1969e2aa401dafdcc1102c26a20e
Autor:
Amy S. Clark, Christina Yau, Denise M. Wolf, Emanuel F. Petricoin, Laura J. van ‘t Veer, Douglas Yee, Stacy L. Moulder, Anne M. Wallace, A. Jo Chien, Claudine Isaacs, Judy C. Boughey, Kathy S. Albain, Kathleen Kemmer, Barbara B. Haley, Hyo S. Han, Andres Forero-Torres, Anthony Elias, Julie E. Lang, Erin D. Ellis, Rachel Yung, Debu Tripathy, Rita Nanda, Julia D. Wulfkuhle, Lamorna Brown-Swigart, Rosa I. Gallagher, Teresa Helsten, Erin Roesch, Cheryl A. Ewing, Michael Alvarado, Erin P. Crane, Meredith Buxton, Julia L. Clennell, Melissa Paoloni, Smita M. Asare, Amy Wilson, Gillian L. Hirst, Ruby Singhrao, Katherine Steeg, Adam Asare, Jeffrey B. Matthews, Scott Berry, Ashish Sanil, Michelle Melisko, Jane Perlmutter, Hope S. Rugo, Richard B. Schwab, W. Fraser Symmans, Nola M. Hylton, Donald A. Berry, Laura J. Esserman, Angela M. DeMichele
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
HER2-targeted therapy improves patient’s outcome in early breast cancer. Here, the authors present the efficacy and biomarker analysis of two HER2-targeted combinations (ado-trastuzumab emtansine plus pertuzumab and paclitaxel, trastuzumab and pert
Externí odkaz:
https://doaj.org/article/e6340916dac6476fac8b24ed5afd32c1
Autor:
Costanza Paoletti, Meredith M. Regan, Samuel M. Niman, Emily M. Dolce, Elizabeth P. Darga, Minetta C. Liu, P. Kelly Marcom, Lowell L. Hart, John W. Smith, Karen L. Tedesco, Eitan Amir, Ian E. Krop, Angela M. DeMichele, Pamela J. Goodwin, Margaret Block, Kimberly Aung, Martha E. Brown, Robert T. McCormack, Daniel F. Hayes
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Circulating tumor cells (CTC) are prognostic in metastatic breast cancer (MBC). The CTC-endocrine therapy index (CTC-ETI), consisting of CTC-ER (estrogen receptor), BCL2, human epidermal growth factor receptor (HER2), and Ki67 expression, mi
Externí odkaz:
https://doaj.org/article/a4591a6d3a9d4069a97a9133183bb04c
Autor:
Sally A.D. Romero, H. Irene Su, Jaya Satagopan, Q. Susan Li, Christina M. Seluzicki, Annika Dries, Angela M. DeMichele, Jun J. Mao
Publikováno v:
Breast, Vol 49, Iss , Pp 48-54 (2020)
Background: Arthralgia is a common and debilitating toxicity of aromatase inhibitors (AI) that leads to premature drug discontinuation. We sought to evaluate the clinical and genetic risk factors associated with AI-associated arthralgia (AIAA). Metho
Externí odkaz:
https://doaj.org/article/32c32034f7e54eec873f7b38b564fe56
Autor:
Justin C. Brown, Kathleen Sturgeon, David B. Sarwer, Andrea B. Troxel, Angela M. DeMichele, Crystal S. Denlinger, Kathryn H. Schmitz
Publikováno v:
Breast Cancer Research and Treatment. 199:109-117
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9182d919c0cd26b3c736d2048b37963e
https://doi.org/10.1007/s10549-023-06868-5
https://doi.org/10.1007/s10549-023-06868-5
Autor:
Amy S. Clark, Fangxin Hong, Richard S. Finn, Angela M. DeMichele, Edith P. Mitchell, James Zwiebel, Fernanda I. Arnaldez, Robert J. Gray, Victoria Wang, Lisa M. McShane, Larry V. Rubinstein, David Patton, P. Mickey Williams, Stanley R. Hamilton, Mehmet S. Copur, Samer S. Kasbari, Ravneet Thind, Barbara A. Conley, Carlos L. Arteaga, Peter J. O'Dwyer, Lyndsay N. Harris, Alice P. Chen, Keith T. Flaherty
Publikováno v:
Clinical Cancer Research. 29:1477-1483
Purpose: Cyclin D/CDK4/6 is critical in controlling the G1 to S checkpoint. CCND, the gene encoding cyclin D, is known to be amplified in a variety of solid tumors. Palbociclib is an oral CDK4/6 inhibitor, approved in advanced breast cancer in combin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0deaba3a14fb4dcac6730d29e90dbb46
https://doi.org/10.1158/1078-0432.ccr-22-2150
https://doi.org/10.1158/1078-0432.ccr-22-2150
Autor:
M, Marczyk, A, Mrukwa, C, Yau, D, Wolf, Y-Y, Chen, R, Balassanian, R, Nanda, B A, Parker, G, Krings, H, Sattar, J C, Zeck, K S, Albain, J C, Boughey, M C, Liu, A D, Elias, A S, Clark, S J, Venters, S, Shad, A, Basu, S M, Asare, M, Buxton, A L, Asare, H S, Rugo, J, Perlmutter, A M, DeMichele, D, Yee, D A, Berry, L Van't, Veer, W F, Symmans, L, Esserman, L, Pusztai
Publikováno v:
Annals of Oncology. 33:814-823
Difference in pathologic complete response (pCR) rate after neoadjuvant chemotherapy does not capture the impact of treatment on downstaging of residual cancer in the experimental arm. We developed a method to compare the entire distribution of resid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742c38117320d51e1e8c6fd63268a5fb
https://doi.org/10.1016/j.annonc.2022.04.072
https://doi.org/10.1016/j.annonc.2022.04.072
Autor:
Justin C Brown, Kathleen Sturgeon, David B Sarwer, Andrea B Troxel, Angela M DeMichele, Crystal S Denlinger, Kathryn H Schmitz
Publikováno v:
Endocrine-Related Cancer. 29:485-493
Insufficient physical activity and obesity are associated with an increased risk of cancer recurrence and death in breast cancer survivors. Sex steroid hormones may mediate these associations. This study tested the hypothesis that exercise and diet,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9f9814ea99434182ec9bc698ab80a7
https://doi.org/10.1530/erc-22-0084
https://doi.org/10.1530/erc-22-0084
Autor:
Mark Jesus M. Magbanua, Lamorna Brown Swigart, Ziad Ahmed, Rosalyn W. Sayaman, Derrick Renner, Ekaterina Kalashnikova, Gillian L. Hirst, Christina Yau, Denise M. Wolf, Wen Li, Amy L. Delson, Smita Asare, Minetta C. Liu, Kathy Albain, A. Jo Chien, Andres Forero-Torres, Claudine Isaacs, Rita Nanda, Debu Tripathy, Angel Rodriguez, Himanshu Sethi, Alexey Aleshin, Matthew Rabinowitz, Jane Perlmutter, W. Fraser Symmans, Douglas Yee, Nola M. Hylton, Laura J. Esserman, Angela M. DeMichele, Hope S. Rugo, Laura J. van ’t Veer
Publikováno v:
Cancer Cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f3f5cb5d242c1d2a9b392f722dfcdc6
https://doi.org/10.1016/j.ccell.2023.04.008
https://doi.org/10.1016/j.ccell.2023.04.008
Autor:
Keith T. Flaherty, Alice P. Chen, Lyndsay N. Harris, Peter J. O'Dwyer, Carlos L. Arteaga, Barbara A. Conley, Ravneet Thind, Samer S. Kasbari, Mehmet S. Copur, Stanley R. Hamilton, P. Mickey Williams, David Patton, Larry V. Rubinstein, Lisa M. McShane, Victoria Wang, Robert J. Gray, Fernanda I. Arnaldez, James Zwiebel, Edith P. Mitchell, Angela M. DeMichele, Richard S. Finn, Fangxin Hong, Amy S. Clark
Representativeness of Study Participants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e238d00836438710bd3e04e5688eb2
https://doi.org/10.1158/1078-0432.22633064.v1
https://doi.org/10.1158/1078-0432.22633064.v1
