Zobrazeno 1 - 10
of 361
pro vyhledávání: '"A M, Bowcock"'
Autor:
Peter J. McGuigan, MB, BCh, BAO, MRCA, FFICM, Emma M. Bowcock, MBBS (Hons), FCICM, Nicholas A. Barrett, FCICM, Bronagh Blackwood, PhD, Andrew J. Boyle, PhD, MRCP, Andrew J. Cadamy, MBChB, FRCA, FFICM, Luigi Camporota, MD, PhD, FRCP, FFICM, FERS, John Conlon, BSc, Matthew E. Cove, MB ChB, Michael A Gillies, MD, FRCA, FRCP, FFICM, Clíona McDowell, MSc, CSTAT, James J. McNamee, MB ChB, Cecilia M. O’Kane, PhD, Alex Puxty, MB ChB, FRCA, MRCP, DICM, FFICM, Malcolm Sim, MD, Rebecca Parsons-Simmonds, BSE, MSc, BSc, Tamas Szakmany, PhD, EDIC, DESA, FRCA, FFICM, FCCM, Neil Young, MBChB, MRCP, FRCA, FFICM, Sam Orde, MBBS, PhD, FCICM, Daniel F. McAuley, MD, FMedSci
Publikováno v:
Critical Care Explorations, Vol 6, Iss 1, p e1028 (2024)
OBJECTIVES:. Lower tidal volume ventilation (targeting 3 mL/kg predicted body weight, PBW) facilitated by extracorporeal carbon dioxide removal (ECCO2R) has been investigated as a potential therapy for acute hypoxemic respiratory failure (AHRF) in th
Externí odkaz:
https://doaj.org/article/5bedbd7c4d664c03bfd82002486052e4
Autor:
Samuel Terkper Ahuno, Anna-Lisa Doebley, Thomas U. Ahearn, Joel Yarney, Nicholas Titiloye, Nancy Hamel, Ernest Adjei, Joe-Nat Clegg-Lamptey, Lawrence Edusei, Baffour Awuah, Xiaoyu Song, Verna Vanderpuye, Mustapha Abubakar, Maire Duggan, Daniel G. Stover, Kofi Nyarko, John M. S. Bartlett, Francis Aitpillah, Daniel Ansong, Kevin L. Gardner, Felix Andy Boateng, Anne M. Bowcock, Carlos Caldas, William D. Foulkes, Seth Wiafe, Beatrice Wiafe-Addai, Montserrat Garcia-Closas, Alexander Kwarteng, Gavin Ha, Jonine D. Figueroa, Paz Polak, the Ghana Breast Health Study Team
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
Abstract Circulating tumor DNA (ctDNA) sequencing studies could provide novel insights into the molecular pathology of cancer in sub-Saharan Africa. In 15 patient plasma samples collected at the time of diagnosis as part of the Ghana Breast Health St
Externí odkaz:
https://doaj.org/article/0fd72a4af12c4bc4bb78096b172d0185
Autor:
Anca Nastase, Amit Mandal, Shir Kiong Lu, Hima Anbunathan, Deborah Morris-Rosendahl, Yu Zhi Zhang, Xiao-Ming Sun, Spyridon Gennatas, Robert C. Rintoul, Matthew Edwards, Alex Bowman, Tatyana Chernova, Tim Benepal, Eric Lim, Anthony Newman Taylor, Andrew G. Nicholson, Sanjay Popat, Anne E. Willis, Marion MacFarlane, Mark Lathrop, Anne M. Bowcock, Miriam F. Moffatt, William O. C. M. Cookson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Pleural mesothelioma is an aggressive malignancy with limited effective therapies. In order to identify therapeutic targets, we integrated SNP genotyping, sequencing and transcriptomics from tumours and low-passage patient-derived cells. Pre
Externí odkaz:
https://doaj.org/article/f4c03b22d13e4a60887cc31103bca100
Autor:
Bianca M. Tod, MMed (Derm), FCDerm, Johann W. Schneider, FCPath (SA) Anat, MMed (Anat Path), Anne M. Bowcock, PhD, Willem I. Visser, MMed (Derm), MFamMed, Maritha J. Kotze, PhD
Publikováno v:
JAAD International, Vol 1, Iss 2, Pp 135-147 (2020)
Dermatologists stand at the gateway of individualization of classification, treatment, and outcomes of acral melanoma patients. The acral melanoma genetic landscape differs in vital ways from that of other cutaneous melanomas. These differences have
Externí odkaz:
https://doaj.org/article/7608a4d68325431ba5c32f4ce46c9ff4
Autor:
Joan Manils, Louise V Webb, Ashleigh Howes, Julia Janzen, Stefan Boeing, Anne M Bowcock, Steven C Ley
Publikováno v:
eLife, Vol 9 (2020)
To investigate how the CARD14E138A psoriasis-associated mutation induces skin inflammation, a knock-in mouse strain was generated that allows tamoxifen-induced expression of the homologous Card14E138A mutation from the endogenous mouse Card14 locus.
Externí odkaz:
https://doaj.org/article/5715b3c4645845bc95c4bf269c9d74b7
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230884 (2020)
Endothelial cells are a primary site of leukocyte recruitment during inflammation. An increase in tumor necrosis factor-alpha (TNFa) levels as a result of infection or some autoimmune diseases can trigger this process. Several autoimmune diseases are
Externí odkaz:
https://doaj.org/article/cc20f204e6b84325b1868b34855d90b8
Autor:
Anca Nastase, Amit Mandal, Shir Kiong Lu, Hima Anbunathan, Deborah Morris‑Rosendahl, Yu Zhi Zhang, Xiao‑Ming Sun, Spyridon Gennatas, Robert C. Rintoul, Matthew Edwards, Alex Bowman, Tatyana Chernova, Tim Benepal, Eric Lim, Anthony Newman Taylor, Andrew G. Nicholson, Sanjay Popat, Anne E. Willis, Marion MacFarlane, Mark Lathrop, Anne M. Bowcock, Miriam F. Moffatt, William O. C. M. Cookson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/64137690744647169fd468ce09fed777
Autor:
Matthew G. Field, Michael A. Durante, Hima Anbunathan, Louis Z. Cai, Christina L. Decatur, Anne M. Bowcock, Stefan Kurtenbach, J. William Harbour
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Uveal melanoma (UM), the most common primary eye cancer, is strongly linked to mutations in the tumor suppressor BAP1. Here, the authors analyze 151 primary UM samples to find that BAP1 and other canonical genomic aberrations arise in an early punctu
Externí odkaz:
https://doaj.org/article/08030f7ca35741a99b1860d184fb1194
Autor:
Frank J. Rauscher, Joseph R. Testa, Eileen J. Kennedy, Joseph Salvino, Anne M. Bowcock, J. William Harbour, S. Bruce Malkowicz, David Hinds, Kasirajan Ayyanathan, Jacob P. Mandell, Surbhi Joshi, Alexander Polo, Paul R. Collop, Mitchell Cheung, Eleonora Sementino, Jeremy W. Prokop, Daniel S. McCracken, Joel Cassel, Hongzhuang Peng
S2. ASXL structure and evolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbaae5bece1e861668ab75b86be99103
https://doi.org/10.1158/1541-7786.22517014.v1
https://doi.org/10.1158/1541-7786.22517014.v1
Autor:
J. William Harbour, Anne M. Bowcock, Ryan S. Lee, Michael D. Onken, Zachary T. Kneass, Katie A. Matatall, Olga A. Agapova, Solange Landreville
PDF file - 2.3MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c887824545009cb3ea12ffce7e67ecf3
https://doi.org/10.1158/1078-0432.22444328.v1
https://doi.org/10.1158/1078-0432.22444328.v1