Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Autor: Peter K. Joshi, Nicola Pirastu, Katherine A. Kentistou, Krista Fischer, Edith Hofer, Katharina E. Schraut, David W. Clark, Teresa Nutile, Catriona L. K. Barnes, Paul R. H. J. Timmers, Xia Shen, Ilaria Gandin, Aaron F. McDaid, Thomas Folkmann Hansen, Scott D. Gordon, Franco Giulianini, Thibaud S. Boutin, Abdel Abdellaoui, Wei Zhao, Carolina Medina-Gomez, Traci M. Bartz, Stella Trompet, Leslie A. Lange, Laura Raffield, Ashley van der Spek, Tessel E. Galesloot, Petroula Proitsi, Lisa R. Yanek, Lawrence F. Bielak, Antony Payton, Federico Murgia, Maria Pina Concas, Ginevra Biino, Salman M. Tajuddin, Ilkka Seppälä, Najaf Amin, Eric Boerwinkle, Anders D. Børglum, Archie Campbell, Ellen W. Demerath, Ilja Demuth, Jessica D. Faul, Ian Ford, Alessandro Gialluisi, Martin Gögele, MariaElisa Graff, Aroon Hingorani, Jouke-Jan Hottenga, David M. Hougaard, Mikko A. Hurme, M. Arfan Ikram, Marja Jylhä, Diana Kuh, Lannie Ligthart, Christina M. Lill, Ulman Lindenberger, Thomas Lumley, Reedik Mägi, Pedro Marques-Vidal, Sarah E. Medland, Lili Milani, Reka Nagy, William E. R. Ollier, Patricia A. Peyser, Peter P. Pramstaller, Paul M. Ridker, Fernando Rivadeneira, Daniela Ruggiero, Yasaman Saba, Reinhold Schmidt, Helena Schmidt, P. Eline Slagboom, Blair H. Smith, Jennifer A. Smith, Nona Sotoodehnia, Elisabeth Steinhagen-Thiessen, Frank J. A. van Rooij, André L. Verbeek, Sita H. Vermeulen, Peter Vollenweider, Yunpeng Wang, Thomas Werge, John B. Whitfield, Alan B. Zonderman, Terho Lehtimäki, Michele K. Evans, Mario Pirastu, Christian Fuchsberger, Lars Bertram, Neil Pendleton, Sharon L. R. Kardia, Marina Ciullo, Diane M. Becker, Andrew Wong, Bruce M. Psaty, Cornelia M. van Duijn, James G. Wilson, J. Wouter Jukema, Lambertus Kiemeney, André G. Uitterlinden, Nora Franceschini, Kari E. North, David R. Weir, Andres Metspalu, Dorret I. Boomsma, Caroline Hayward, Daniel Chasman, Nicholas G. Martin, Naveed Sattar, Harry Campbell, Tōnu Esko, Zoltán Kutalik, James F. Wilson

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)

Variability in human longevity is genetically influenced. Using genetic data of parental lifespan, the authors identify associations at HLA-DQA/DRB1 and LPA and find that genetic variants that increase educational attainment have a positive effect on

Externí odkaz: https://doaj.org/article/71f6e3ed3cbf4216a67afc3e8eda8b11

Intra-operative protective mechanical ventilation in lung transplantation: a randomised, controlled trial

Autor: Stuart Hastings, Aislin C. Meehan, Jade Jaffar, Paul S. Myles, G. L. Verbeek, Silvana Marasco, Glen P. Westall, Enjarn Lin

Publikováno v: Anaesthesia. 72:993-1004

Summary Primary graft dysfunction occurs in up to 25% of patients after lung transplantation. Contributing factors include ventilator-induced lung injury, cardiopulmonary bypass, ischaemia-reperfusion injury and excessive fluid administration. We eva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5181b34204dbcdb712968c2d8144ea06
https://doi.org/10.1111/anae.13964

Intraoperative protective ventilation strategies in lung transplantation

Autor: Paul S. Myles, Genna L. Verbeek

Publikováno v: Transplantation Reviews. 27:30-35

Primary graft dysfunction (PGD) occurs in up to 25% of patients after lung transplantation. One method of reducing the risk of developing PGD is to incorporate a protective ventilation strategy in the donor, as well as after allograft implantation in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d9b03c0f5667e40fe18c98caa2b9e1a
https://doi.org/10.1016/j.trre.2012.11.004

An attempt at the interpretation of the ligand hyperfine structure in the epr-spectra of mox 52⊖ -ions

Autor: J. L. Verbeek, P. F. Cornaz

Publikováno v: Recueil des Travaux Chimiques des Pays-Bas. 86:209-219

In this contribution we propose a simple model for the observed ligand hyperfine structure in complexes of the type MOX (where M = Cr, Mo, W and X = F, Br), in the limits of the less complicated case I = ½ as is realised with F as the ligand. It is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::83a19e2e2216bdfa223e9d4d67c104f2
https://doi.org/10.1002/recl.19670860212

Hypoalbuminemia in Donors with Twin-Twin Transfusion Syndrome

Autor: Christian V. Hulzebos, Dick Oepkes, Enrico Lopriore, L. Verbeek, Johanna M. Middeldorp, Frans J. Walther

Publikováno v: Fetal Diagnosis and Therapy, 33(2), 98-102. KARGER
Fetal Diagnosis and Therapy, 33(2), 98-102

Objective: To estimate the differences in albumin levels between donors and recipients with twin-twin transfusion syndrome (TTTS). Methods: We performed a matched case-control study including twin pairs with TTTS treated conservatively (conservative

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8081633d0b846b0d45c17353f6c9496
https://research.rug.nl/en/publications/f1101460-4205-4334-b7d6-f6bfb08ffe5b