Zobrazeno 1 - 10
of 524
pro vyhledávání: '"A L Meredith"'
Autor:
Ria L. Dinsdale, Andrea L. Meredith
Publikováno v:
Channels, Vol 18, Iss 1 (2024)
Variants in KCNMA1, encoding the voltage- and calcium-activated K+ (BK) channel, are associated with human neurological disease. The effects of gain-of-function (GOF) and loss-of-function (LOF) variants have been predominantly studied on BK channel c
Externí odkaz:
https://doaj.org/article/cbec9ee4309246189d702c30837c6248
Autor:
Emma C Hobbs, Jessica L Porter, Jean Y H Lee, Panayiotis Loukopoulos, Pam Whiteley, Lee F Skerratt, Timothy P Stinear, Katherine B Gibney, Anna L Meredith
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 11, p e0012189 (2024)
Buruli ulcer (BU) is a neglected tropical disease of skin and subcutaneous tissues caused by Mycobacterium ulcerans. BU-endemic areas are highly focal, and M. ulcerans transmission dynamics vary by setting. In Victoria, Australia, BU is an endemic ve
Externí odkaz:
https://doaj.org/article/d6d779a1ac4a443abe5191cf5f134083
Autor:
Zijie Zhou, Anouk van Hooij, Gaby N. Wassenaar, Emma Seed, Els M. Verhard-Seymonsbergen, Paul L. A. M. Corstjens, Anna L. Meredith, Liam A. Wilson, Elspeth M. Milne, Katie M. Beckmann, Annemieke Geluk
Publikováno v:
Animals, Vol 14, Iss 13, p 2005 (2024)
Leprosy is a poverty-associated infectious disease in humans caused by Mycobacterium leprae or M. lepromatosis, often resulting in skin and peripheral nerve damage, which remains a significant public health concern in isolated areas of low- and middl
Externí odkaz:
https://doaj.org/article/b40ea891d5b642798630eeb7688a129d
Autor:
Hans J. Moldenhauer, Ria L. Dinsdale, Sara Alvarez, Alberto Fernández-Jaén, Andrea L. Meredith
Publikováno v:
Current Research in Physiology, Vol 5, Iss , Pp 404-413 (2022)
BK K+ channels are critical regulators of neuron and muscle excitability, comprised of a tetramer of pore-forming αsubunits from the KCNMA1 gene and cell- and tissue-selective β subunits (KCNMB1-4). Mutations in KCNMA1 are associated with neurologi
Externí odkaz:
https://doaj.org/article/737c53f79ea148cf98936af77eadc7ce
Autor:
Ricardo D. Santander, Fatemeh Khodadadi, Christopher L. Meredith, Željko Rađenović, Jon Clements, Srđan G. Aćimović
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Erwinia amylovora causes fire blight, a disease responsible for enormous economic losses in the pome fruit-producing areas where it is present. Despite the abundant research on fire blight, information about E. amylovora population dynamics and survi
Externí odkaz:
https://doaj.org/article/9481c6c2912d4954b046c4cec69f0615
Autor:
Claire R. Brandenburger, Martin Kim, Eve Slavich, Floret L. Meredith, Juha‐Pekka Salminen, William B. Sherwin, Angela T. Moles
Publikováno v:
Ecology and Evolution, Vol 10, Iss 12, Pp 5451-5463 (2020)
Abstract The enemy release hypothesis is often cited as a potential explanation for the success of introduced plants; yet, empirical evidence for enemy release is mixed. We aimed to quantify changes in herbivory and defense in introduced plants while
Externí odkaz:
https://doaj.org/article/5e26153c320a48d1ba1dd0c7b182e696
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Daily regulation of Ca2+– and voltage-activated BK K+ channel activity is required for action potential rhythmicity in the suprachiasmatic nucleus (SCN) of the hypothalamus, the brain's circadian clock. In SCN neurons, BK activation is dependent up
Externí odkaz:
https://doaj.org/article/10cce6cba9134410abeb22592bdc835a
Publikováno v:
Biophysical Reports, Vol 1, Iss 1, Pp 100005- (2021)
Circadian rhythms in mammals are coordinated by the central clock in the brain, located in the suprachiasmatic nucleus (SCN). Multiple molecular and cellular signals display a circadian variation within SCN neurons, including intracellular Ca2+, but
Externí odkaz:
https://doaj.org/article/3c0c5f1feee04870a65b520ea1a22206
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Inner ear hair cells form synapses with afferent terminals and afferent neurons carry signals as action potentials to the central nervous system. Efferent neurons have their origins in the brainstem and some make synaptic contact with afferent dendri
Externí odkaz:
https://doaj.org/article/30c2586f34ca488b938e7cd36ff70224
Publikováno v:
Cancer. 129:890-900
Adjuvant capecitabine is considered a standard of care for resected cholangiocarcinoma per the BILCAP trial. The role of adjuvant radiation therapy in that trial was not addressed. This study was designed to examine the outcomes of adjuvant radiation