Zobrazeno 1 - 6 of 6 pro vyhledávání: '"A L Goodsall"'
1
Unimpaired autoreactive T-cell traffic within the central nervous system during tumor necrosis factor receptor-mediated inhibition of experimental autoimmune encephalomyelitis
Autor: Anna L. Goodsall, Jonathon D. Sedgwick, John Ghrayeb, Frances A. Lemckert, Andrew L. Ford, Heinrich Körner, Bernard Scallon
Publikováno v: Proceedings of the National Academy of Sciences. 92:11066-11070
The critical role of tumor necrosis factor (TNF) as a mediator in autoimmune inflammatory processes is evident from in vivo studies with TNF-blocking agents. However, the mechanisms by which TNF, and possibly also its homologue lymphotoxin alpha, con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d7a2296164070ad60a73787085e0e7
https://doi.org/10.1073/pnas.92.24.11066
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2
Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared
Autor: A L Ford, A L Goodsall, W F Hickey, J D Sedgwick
Publikováno v: The Journal of Immunology. 154:4309-4321
Ramified microglia in the adult central nervous system (CNS) are the principal glial element up-regulating MHC class I and II expression in response to inflammatory events or neuronal damage. A proportion of these cells also express MHC class II cons
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26a6f15455bb453a507d678460907930
https://doi.org/10.4049/jimmunol.154.9.4309
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3
Identification of human T cell epitopes in the Mycobacterium leprae heat shock protein 70-kD antigen
Autor: Elizabeth Adams, Warwick J. Britton, Antony Basten, A. L. Goodsall, A. Morgan
Publikováno v: Clinical and Experimental Immunology. 94:500-506
SUMMARY In a number of pathogens, heat shock proteins (hsp) stimulate humoral and cellular immune responses despite significant sequence identity with host hsp. The 70-kD hsp of Mycobacterium leprae, whieh shares 47% identity with human hsp70 at the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f4ac4b614f46f6390f1388c743cb79
https://doi.org/10.1111/j.1365-2249.1993.tb08225.x
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4
Tissue digestion with dispase substantially reduces lymphocyte and macrophage cell-surface antigen expression
Autor: Anna L. Goodsall, Jonathon D. Sedgwick, Andrew L. Ford, Eléna Foulcher
Publikováno v: Journal of immunological methods. 194(1)
Dispase was used to digest central nervous system (CNS) tissue for isolation of the fixed tissue macrophage population (CNS microglia) and other leucocytes present. An apparent reduction in expression of some leucocyte cell surface markers was invest
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d06173bf7f12702dcf70bf2c286e7c7
https://pubmed.ncbi.nlm.nih.gov/8690942
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5
Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared
Autor: A L, Ford, A L, Goodsall, W F, Hickey, J D, Sedgwick
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 154(9)
Ramified microglia in the adult central nervous system (CNS) are the principal glial element up-regulating MHC class I and II expression in response to inflammatory events or neuronal damage. A proportion of these cells also express MHC class II cons
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::45e404deb1c0e5eeb6011b33399f9ac6
https://pubmed.ncbi.nlm.nih.gov/7722289
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