Zobrazeno 1 - 10
of 1 712
pro vyhledávání: '"A L Fletcher"'
Autor:
Michael Agrez, Christopher Chandler, Kristofer J. Thurecht, Nicholas L. Fletcher, Feifei Liu, Gayathri Subramaniam, Christopher B. Howard, Stephen Parker, Darryl Turner, Justyna Rzepecka, Gavin Knox, Anastasia Nika, Andrew M. Hall, Hayley Gooding, Laura Gallagher
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract The identification of adjuvants to improve vaccination efficacy is a major unmet need. One approach is to augment the functionality of dendritic cells (DCs) by using Toll-like receptor-9 (TLR9) agonists such as cytosine-phosphate-guanine oli
Externí odkaz:
https://doaj.org/article/7a51c439ab39409a885cbdbbf60e0eef
Autor:
L. David Carter, Donna Christensen, David M. Hopkins, John V. Matthews, Robert E. Nelson, Lynn E. Ovenden, Natalia Rybczynski, Tamara L. Fletcher
Publikováno v:
Arctic, Antarctic, and Alpine Research, Vol 56, Iss 1 (2024)
Motivated by the need for more paleodata for Pliocene paleoclimate data-model comparison, we revisited unpublished investigations of a fossiliferous site on the Niguanak River in Arctic North America. Analyses of the samples indicates forested condit
Externí odkaz:
https://doaj.org/article/29317c716f5848ca956364b559a70c96
Autor:
Nick Schafstall, Xavier Benito, Sandra O Brugger, Althea L Davies, Erle Ellis, Sergi Pla-Rabes, Alicja Bonk, M Jane Bunting, Frank M Chambers, Suzette G A Flantua, Tamara L Fletcher, Caroline Greiser, Armand Hernández, Benjamin Gwinneth, Gerbrand Koren, Katarzyna Marcisz, Encarni Montoya, Adolfo Quesada-Román, Amila S Ratnayake, Pierre Sabatier, John P Smol, Nancy Y Suárez-Mozo
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 10, p e1012487 (2024)
Owing to its specialised methodology, palaeoecology is often regarded as a separate field from ecology, even though it is essential for understanding long-term ecological processes that have shaped the ecosystems that ecologists study and manage. Des
Externí odkaz:
https://doaj.org/article/c37fa2972bc44fb1ae2cea3489932e70
Autor:
Allie N. Townsend, Israel C. Christie, Shubhada Sansgiry, Natalie E. Hundt, Matthew Escamilla, Hardeep Singh, Mark E. Kunik, Melinda A. Stanley, Terri L. Fletcher
Publikováno v:
Psychiatry Research Communications, Vol 4, Iss 3, Pp 100184- (2024)
This retrospective study sought to identify patient-, provider-, and system-level characteristics associated with anxiety diagnostic specificity in mental health clinics in the Veterans Health Administration. It used administrative data extracted fro
Externí odkaz:
https://doaj.org/article/1163f272453242b98a544f51fb3d53b9
Autor:
Natalie E. King, Jo-Maree Courtney, Lachlan S. Brown, Alastair J. Fortune, Nicholas B. Blackburn, Jessica L. Fletcher, Jake M. Cashion, Jana Talbot, Alice Pébay, Alex W. Hewitt, Gary P. Morris, Kaylene M. Young, Anthony L. Cook, Brad A. Sutherland
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background Pericytes are multifunctional contractile cells that reside on capillaries. Pericytes are critical regulators of cerebral blood flow and blood–brain barrier function, and pericyte dysfunction may contribute to the pathophysiolog
Externí odkaz:
https://doaj.org/article/c8c8c85bb5db476ea1a3b1f8afc26262
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss, characterised by the dysfunction and death of the photoreceptors and retinal pigment epithelium (RPE). Innate immune cell activation and accompanying para
Externí odkaz:
https://doaj.org/article/d413f7a802f14a9ba28097a5708dbb74
Autor:
Samuel Kraus, Megan L Fletcher, Urszula Łapińska, Krina Chawla, Evan Baker, Erin L Attrill, Paul O'Neill, Audrey Farbos, Aaron Jeffries, Edouard E Galyov, Sunee Korbsrisate, Kay B Barnes, Sarah V Harding, Krasimira Tsaneva-Atanasova, Mark A T Blaskovich, Stefano Pagliara
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012361 (2024)
The interactions between a virus and its host vary in space and time and are affected by the presence of molecules that alter the physiology of either the host or the virus. Determining the molecular mechanisms at the basis of these interactions is p
Externí odkaz:
https://doaj.org/article/b6c3583e1ed849f4a0d265bd93bc466b
Publikováno v:
AERA Open, Vol 10 (2024)
When it comes to understanding the consequences of school absenteeism, how missing school might be linked to student-teacher relationships remains relatively unexplored. Our work helps to further detail this context by specifically investigating whet
Externí odkaz:
https://doaj.org/article/dba6c536d1ca4060a818bcbf1b706d63
Autor:
Michael Agrez, Christopher Chandler, Kristofer J. Thurecht, Nicholas L. Fletcher, Feifei Liu, Gayathri Subramaniam, Christopher B. Howard, Benjamin Blyth, Stephen Parker, Darryl Turner, Justyna Rzepecka, Gavin Knox, Anastasia Nika, Andrew M. Hall, Hayley Gooding, Laura Gallagher
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Cancers and autoimmune diseases commonly co-exist and immune checkpoint inhibitor therapy (ICI) exacerbates autoimmune pathologies. We recently described a lipidic peptide, designated IK14004, that promotes expansion of immunosuppressive T r
Externí odkaz:
https://doaj.org/article/e0f0af9605974d5ea5748b35c3c11dc8
Autor:
Xinying Jia, Yanni K.-Y. Chin, Alan H. Zhang, Theo Crawford, Yifei Zhu, Nicholas L. Fletcher, Zihan Zhou, Brett R. Hamilton, Martin Stroet, Kristofer J. Thurecht, Mehdi Mobli
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-10 (2023)
Head-to-tail macrocyclization of proteins and peptides can increase their structural stability, however, potential polymerization can lead to reduced yields. Here, the authors report the engineering of self-cyclizing ‘autocyclase’ proteins to gen
Externí odkaz:
https://doaj.org/article/e22b7329d2fa42c78900ee527f8a1241