Zobrazeno 1 - 10
of 226
pro vyhledávání: '"A L Calder"'
Autor:
Qiuying Chen, Csaba Konrad, Davinder Sandhu, Dipa Roychoudhury, Benjamin I. Schwartz, Roger R. Cheng, Kirsten Bredvik, Hibiki Kawamata, Elizabeth L. Calder, Lorenz Studer, Steven.M. Fischer, Giovanni Manfredi, Steven.S. Gross
Publikováno v:
Neurobiology of Disease, Vol 144, Iss , Pp 105025- (2020)
Amyotrophic lateral sclerosis is a disease characterized by progressive paralysis and death. Most ALS-cases are sporadic (sALS) and patient heterogeneity poses challenges for effective therapies. Applying metabolite profiling on 77-sALS patient-deriv
Externí odkaz:
https://doaj.org/article/ad99be7da6fb4c3da25d56989ffa2ba8
Autor:
Cedrina L. Calder, MD, MSPH, Heather O’Hara, MD, MSPH, Mohammad Tabatabai, PhD, Celia J. Maxwell, MD, Salisha Marryshow, MPH, Aima A. Ahonkhai, MD, MPH, Carolyn M. Audet, PhD, MPH, C. William Wester, MD, MPH, Muktar H. Aliyu, MD, DrPH
Publikováno v:
International Journal of Maternal and Child Health and AIDS, Vol 9, Iss 1 (2020)
Objective: Adherence to combination antiretroviral therapy (ART) among pregnant women is essential to attaining the goal of eliminating mother-to-child HIV transmission. The objective of this study was to determine which factors affect adherence to A
Externí odkaz:
https://doaj.org/article/55f30d10d9e74fd59d85c418ee65e2b2
Publikováno v:
Cells, Vol 10, Iss 2, p 396 (2021)
Retinal vascular diseases have distinct, complex and multifactorial pathogeneses yet share several key pathophysiological aspects including inflammation, vascular permeability and neovascularisation. In non-infectious posterior uveitis (NIU), retinal
Externí odkaz:
https://doaj.org/article/8d65c773d1a449dab94bf6ae4fb69688
Autor:
Arnulf Hertweck, Catherine M. Evans, Malihe Eskandarpour, Jonathan C.H. Lau, Kristine Oleinika, Ian Jackson, Audrey Kelly, John Ambrose, Peter Adamson, David J. Cousins, Paul Lavender, Virginia L. Calder, Graham M. Lord, Richard G. Jenner
Publikováno v:
Cell Reports, Vol 15, Iss 12, Pp 2756-2770 (2016)
The transcription factor T-bet directs Th1 cell differentiation, but the molecular mechanisms that underlie this lineage-specific gene regulation are not completely understood. Here, we show that T-bet acts through enhancers to allow the recruitment
Externí odkaz:
https://doaj.org/article/62e0042e1c2743aca84f38295c4cab13
Autor:
Rose M. Gilbert, Xiaozhe Zhang, Robert D. Sampson, Michael R. Ehrenstein, Dao X. Nguyen, Mahid Chaudhry, Charles Mein, Nadiya Mahmud, Grazyna Galatowicz, Oren Tomkins-Netzer, Virginia L. Calder, Sue Lightman
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
BackgroundNon-infectious uveitis can cause chronic relapsing and remitting ocular inflammation, which may require high dose systemic immunosuppression to prevent severe sight loss. It has been classically described as an autoimmune disease, mediated
Externí odkaz:
https://doaj.org/article/b42b99a840f043ffb206c156e89239dc
Autor:
Homa Majd, Sadaf Amin, Zaniar Ghazizadeh, Andrius Cesiulis, Edgardo Arroyo, Karen Lankford, Sina Farahvashi, Angeline K. Chemel, Mesomachukwu Okoye, Megan D. Scantlen, Jason Tchieu, Elizabeth L. Calder, Valerie Le Rouzic, Abolfazl Arab, Hani Goodarzi, Gavril Pasternak, Jeffery D. Kocsis, Shuibing Chen, Lorenz Studer, Faranak Fattahi
SUMMARYSchwann cells (SCs) are the myelinating and non-myelinating glia of the peripheral nervous system (PNS) and are essential for its function. Defects in SCs are associated with many PNS disorders including diabetic peripheral neuropathy (DPN), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b182cb5235be51e28d5f3a475ae785c0
https://doi.org/10.1101/2022.08.16.504209
https://doi.org/10.1101/2022.08.16.504209
Autor:
Homa Majd, Sadaf Amin, Zaniar Ghazizadeh, Andrius Cesiulis, Edgardo Arroyo, Karen Lankford, Alireza Majd, Sina Farahvashi, Angeline K. Chemel, Mesomachukwu Okoye, Megan D. Scantlen, Jason Tchieu, Elizabeth L. Calder, Valerie Le Rouzic, Bradley Shibata, Abolfazl Arab, Hani Goodarzi, Gavril Pasternak, Jeffery D. Kocsis, Shuibing Chen, Lorenz Studer, Faranak Fattahi
Publikováno v:
Cell Stem Cell. 30:632-647.e10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e291548b5a070d937c6a599f6a86596e
https://doi.org/10.1016/j.stem.2023.04.006
https://doi.org/10.1016/j.stem.2023.04.006
Autor:
Wynne Weston-Davies, Virginia L. Calder, Malihe Eskandarpour, Sarah E. Coupland, Miles A. Nunn, Yi-Hsing Chen
Publikováno v:
The American Journal of Pathology. 191:320-334
Nomacopan, a drug originally derived from tick saliva, has dual functions of sequestering leukotriene B4 (LTB4) and inhibiting complement component 5 (C5) activation. Nomacopan has been shown to provide therapeutic benefit in experimental autoimmune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a64a7e26ecb63b7fe16916c92b9a531
https://doi.org/10.1016/j.ajpath.2020.10.010
https://doi.org/10.1016/j.ajpath.2020.10.010
Autor:
Emiliano Hergenreder, Yana Zorina, Zeping Zhao, Hermany Munguba, Elizabeth L. Calder, Arianna Baggiolini, Andrew P. Minotti, Ryan M. Walsh, Conor Liston, Joshua Levitz, Ralph Garippa, Shuibing Chen, Gabriele Ciceri, Lorenz Studer
The maturation of human pluripotent stem cell (hPSC)-derived neurons mimics the protracted timing of human brain development, extending over months and years to reach adult-like function. Prolonged in vitro maturation presents a major challenge to st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::655ad4d0d3b48af1879101ff0d14a612
https://doi.org/10.1101/2022.06.02.494616
https://doi.org/10.1101/2022.06.02.494616
Autor:
Virginia L. Calder, Susan Lightman, G. Galatowicz, Renyang Gu, Xiaozhe Zhang, Aurelia Gondrand, Y.–H. Chen, Malihe Eskandarpour
Publikováno v:
European Journal of Immunology. 50:1941-1951
Immunopathogenic roles for both Th1 (CD4+ IFN-γ+ ) and Th17 (CD4+ IL-17A+ ) cells have been demonstrated in experimental autoimmune uveitis (EAU). However, the role for Th17/Th1 (CD4+ T cells co-expressing IFN-γ and IL-17A) cells in EAU is not yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7c51e3ddf1d1c43c6f66ee96c184dae
https://doi.org/10.1002/eji.202048616
https://doi.org/10.1002/eji.202048616