Zobrazeno 1 - 10
of 281
pro vyhledávání: '"A L Bychkov"'
Autor:
Aizek B. Isaev, Maxim L. Bychkov, Dmitrii S. Kulbatskii, Alexander A. Andreev-Andrievskiy, Mikhail A. Mashkin, Mikhail A. Shulepko, Olga V. Shlepova, Eugene V. Loktyushov, Alexander V. Latanov, Mikhail P. Kirpichnikov, Ekaterina N. Lyukmanova
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Intellectual disability and autistic features are associated with chromosome region 2q23.q23.2 duplication carrying LYPD6 and LYPD6B genes. Here, we analyzed LYPD6 and LYPD6B expression in patients with different neuropsychiatric disorders.
Externí odkaz:
https://doaj.org/article/2ae1874777974e35a3cdb4490b504935
Autor:
O. V. Shlepova, M. A. Shulepko, V. O. Shipunova, M. L. Bychkov, I. D. Kukushkin, I. A. Chulina, V. N. Azev, E. I. Shramova, V. A. Kazakov, A. M. Ismailova, Y. A. Palikova, V. A. Palikov, E. A. Kalabina, E. A. Shaykhutdinova, G. A. Slashcheva, E. A. Tukhovskaya, I. A. Dyachenko, A. N. Murashev, S. M. Deyev, M. P. Kirpichnikov, Z. O. Shenkarev, E. N. Lyukmanova
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
α7-Type nicotinic acetylcholine receptor (α7-nAChR) promotes the growth and metastasis of solid tumors. Secreted Ly6/uPAR-Related Protein 1 (SLURP-1) is a specific negative modulator of α7-nAChR produced by epithelial cells. Here, we investigated
Externí odkaz:
https://doaj.org/article/68ca419785d04cd79f6b4a41671b974e
Autor:
Zakhar O. Shenkarev, Yuri M. Chesnokov, Maxim M. Zaigraev, Anton O. Chugunov, Dmitrii S. Kulbatskii, Milita V. Kocharovskaya, Alexander S. Paramonov, Maxim L. Bychkov, Mikhail A. Shulepko, Dmitry E. Nolde, Roman A. Kamyshinsky, Evgeniy O. Yablokov, Alexey S. Ivanov, Mikhail P. Kirpichnikov, Ekaterina N. Lyukmanova
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
The membrane plays a key role in the interaction of non-conventional neurotoxins with the nicotinic receptors.
Externí odkaz:
https://doaj.org/article/54654b9e8be64f4eba0aad318a544d08
Autor:
Ekaterina N. Lyukmanova, Maxim M. Zaigraev, Dmitrii S. Kulbatskii, Aizek B. Isaev, Ilya D. Kukushkin, Maxim L. Bychkov, Mikhail A. Shulepko, Anton O. Chugunov, Mikhail P. Kirpichnikov
Publikováno v:
Toxins, Vol 15, Iss 10, p 612 (2023)
Cancer progression is characterized by microenvironmental acidification. Tumor cells adapt to low environmental pH by activating acid-sensing trimeric ion channels of the DEG/ENaC family. The α-ENaC/ASIC1a/γ-ENaC heterotrimeric channel is a tumor-s
Externí odkaz:
https://doaj.org/article/dfc5d92e10344ed5904eaa6a5cb5eb24
Autor:
Maxim L. Bychkov, Aizek B. Isaev, Alexander A. Andreev-Andrievskiy, Konstantin Petrov, Alexander S. Paramonov, Mikhail P. Kirpichnikov, Ekaterina N. Lyukmanova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14852 (2023)
Alzheimer disease (AD) is a widespread neurodegenerative disease characterized by the accumulation of oligomeric toxic forms of β-amyloid (Aβ1-42) and dysfunction of the cholinergic system in the different brain regions. However, the exact mechanis
Externí odkaz:
https://doaj.org/article/d5af1bfee7fe46589da1141e77d6a539
Autor:
Anastasia V. Sudarikova, Maxim L. Bychkov, Dmitrii S. Kulbatskii, Vladislav I. Chubinskiy-Nadezhdin, Olga V. Shlepova, Mikhail A. Shulepko, Sergey G. Koshelev, Mikhail P. Kirpichnikov, Ekaterina N. Lyukmanova
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Lung cancer is one of the most common cancer types in the world. Despite existing treatment strategies, overall patient survival remains low and new targeted therapies are required. Acidification of the tumor microenvironment drives the growth and me
Externí odkaz:
https://doaj.org/article/1790649e29a24969afaa70ad2b6fc156
Autor:
Maxim L. Bychkov, Mikhail A. Shulepko, Olga V. Shlepova, Dmitrii S. Kulbatskii, Irina A. Chulina, Alexander S. Paramonov, Ludmila K. Baidakova, Viatcheslav N. Azev, Sergey G. Koshelev, Mikhail P. Kirpichnikov, Zakhar O. Shenkarev, Ekaterina N. Lyukmanova
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Secreted Ly6/uPAR-related protein 1 (SLURP-1) is a secreted Ly6/uPAR protein that negatively modulates the nicotinic acetylcholine receptor of α7 type (α7-nAChR), participating in control of cancer cell growth. Previously we showed, that a recombin
Externí odkaz:
https://doaj.org/article/4ea1ae5dc8d1418182e8d7e2d15ebd4d
Autor:
Karina V. Gavrilova, Aleksey L. Bychkov, Elena S. Bychkova, Zoya A. Akimenko, Aleksandr A. Chernonosov, Yurii A. Kalambet, Oleg I. Lomovskii
Publikováno v:
Foods and Raw Materials, Vol 7, Iss 2, Pp 255-263 (2019)
A poor consumption of important nutrients triggered a public interest in functional foods that contain easy-to-digest proteins. The present research features fractionation, mechanical activation, and enzymatic hydrolysis of pea protein. According to
Externí odkaz:
https://doaj.org/article/38b359478a884a41bf5cea53ee45127c
Autor:
Alexander S. Paramonov, Mikhail A. Shulepko, Alexey M. Makhonin, Maxim L. Bychkov, Dmitrii S. Kulbatskii, Andrey M. Chernikov, Mikhail Yu. Myshkin, Sergey V. Shabelnikov, Zakhar O. Shenkarev, Mikhail P. Kirpichnikov, Ekaterina N. Lyukmanova
Publikováno v:
Marine Drugs, Vol 20, Iss 8, p 503 (2022)
Three-finger proteins (TFPs) are small proteins with characteristic three-finger β-structural fold stabilized by the system of conserved disulfide bonds. These proteins have been found in organisms from different taxonomic groups and perform various
Externí odkaz:
https://doaj.org/article/c9dc58cc334d4852948d18e54962e1f7
Publikováno v:
JETP Letters. 117:435-440
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b56d619e0eb858b6d84916e9cd678e96
https://doi.org/10.1134/s0021364023600362
https://doi.org/10.1134/s0021364023600362