Výsledky vyhledávání

Point-of-Care: Roadmap for Analytical Characterization and Validation of a High-Sensitivity Cardiac Troponin I Assay in Plasma and Whole Blood Matrices

Autor: Robert H, Christenson, Lisa D S, Frenk, Henk J, de Graaf, Trees S Y, van Domburg, Frank P G, Wijnands, Helma W J, Foolen, Danielle W M, Kemper, Anne L, Bruinen, Bernadet D M, Meijering, Judith M, Fonville, Femke K, de Theije

Publikováno v: The Journal of Applied Laboratory Medicine. 7:971-988

Background High-sensitivity cardiac troponin (hs-cTn) assays enable more precise use of traditional diagnostic strategies and earlier rule-out/rule-in at 0/1 h or 0/2 h after presentation of acute myocardial infarction (AMI). Availability of hs-cTn m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56815081af0c3f2b462293d858a13f6
https://doi.org/10.1093/jalm/jfac028

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Point-of-care high-sensitivity troponin-I analysis in capillary blood for acute coronary syndrome diagnostics

Autor: Anne L. Bruinen, Lisa D.S. Frenk, Femke de Theije, Daniëlle W.M. Kemper, Marcel J.W. Janssen, Braim M. Rahel, Joan G. Meeder, Arnoud W.J. van ‘t Hof

Publikováno v: Clinical chemistry and laboratory medicineReferences. 60(10)

Objectives Patients with acute coronary syndrome (ACS) should be referred promptly to the hospital to reduce mortality and morbidity. Differentiating between low-risk and high-risk patients remains a diagnostic challenge. Point-of-care testing can co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c557039cede696442a2a9d75b67517d
https://pubmed.ncbi.nlm.nih.gov/35858956

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URGENT 1.5: diagnostic accuracy of the modified HEART score, with fingerstick point-of-care troponin testing, in ruling out acute coronary syndrome

Autor: L D S Frenk, M J W Janssen, A L Bruinen, F H M van Osch, L H Koper, J G Meeder, A. W. J. van ’t Hof, B M Rahel

Publikováno v: Netherlands Heart Journal, 30(7-8), 360-369. Bohn Stafleu van Loghum

Background The HEART score is a validated risk stratification tool for chest pain patients presenting to the emergency department and was recently investigated for implementation in a pre-hospital setting. Fingerstick (capillary blood) point-of-care

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0276b5b67f573710b5984a1ab056f417
https://pubmed.ncbi.nlm.nih.gov/34817832

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Identification and High-Resolution Imaging of alpha-Tocopherol from Human Cells to Whole Animals by TOF-SIMS Tandem Mass Spectrometry

Autor: Gregory L. Fisher, Ron M. A. Heeren, Rachelle Balez, Anne L. Bruinen, Astrid M. van der Sar, Lezanne Ooi

Publikováno v: Journal of the American Society for Mass Spectrometry, 29(8), 1571-1581. Springer, Cham
Journal of the American Society for Mass Spectrometry
Bruinen, A L, Fisher, G L, Balez, R, van der Sar, A M, Ooi, L & Heeren, R M A 2018, ' Identification and High-Resolution Imaging of α-Tocopherol from Human Cells to Whole Animals by TOF-SIMS Tandem Mass Spectrometry ', Journal of the American Society for Mass Spectrometry, vol. 29, no. 8, pp. 1571-1581 . https://doi.org/10.1007/s13361-018-1979-x
Journal of the American Society for Mass Spectrometry, 29(8), 1571-1581. Springer New York

A unique method for identification of biomolecular components in different biological specimens, while preserving the capability for high speed 2D and 3D molecular imaging, is employed to investigate cellular response to oxidative stress. The employe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9099465ebbac4544dd9ff4ac69a8ee19
https://cris.maastrichtuniversity.nl/en/publications/bd65c64e-ca1f-4ce2-8c1e-065eafb50049

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Multimodal Spectroscopic Study of Amyloid Fibril Polymorphism

Autor: Mischa Bonn, Volker Deckert, Gijsje H. Koenderink, Michael Schleeger, Krassimir P. Velikov, Corianne C. vandenAkker, Anne L. Bruinen, Ron M. A. Heeren, Tanja Deckert-Gaudig

Publikováno v: Journal of Physical Chemistry B, 120(34), 8809-8817. American Chemical Society
The journal of Physical Chemistry. B, 120(34), 8809-8817. American Chemical Society

Amyloid fibrils are a large class of self-assembled protein aggregates that are formed from unstructured peptides and unfolded proteins. The fibrils are characterized by a universal β-sheet core stabilized by hydrogen bonds, but the molecular struct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6d8871e2a4fe2eecae15b563c2b96f
https://doi.org/10.1021/acs.jpcb.6b05339

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Characterization of lipidic markers of chondrogenic differentiation using mass spectrometry imaging

Autor: Cristina Ruiz-Romero, Beatriz Rocha, Ron M. A. Heeren, Berta Cillero-Pastor, Francisco J. Blanco, Anne L. Bruinen, Gert B. Eijkel

Publikováno v: Proteomics, 15(4), 702-13. Wiley-VCH Verlag

Mesenchymal stem cells (MSC) are an interesting alternative for cell-based therapy of cartilage defects attributable to their capacity to differentiate toward chondrocytes in the process termed chondrogenesis. The metabolism of lipids has recently be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb1a2274adc642c32726a649cf653d0
https://doi.org/10.1002/pmic.201400260

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ToF-SIMS Parallel Imaging MS/MS of Lipid Species in Thin Tissue Sections

Autor: Gregory L. Fisher, Anne L. Bruinen, Ron M. A. Heeren

Publikováno v: Methods in Molecular Biology ISBN: 9781493970506

Unambiguous identification of detected species is essential in complex biomedical samples. To date, there are not many mass spectrometry imaging techniques that can provide both high spatial resolution and identification capabilities. A new and paten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b849c5c6ccbcd8ccf4bba4cee293a701
https://doi.org/10.1007/978-1-4939-7051-3_14

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Efficient functionalization of additives at supramolecular material surfaces

Autor: Ojgm Olga Goor, Pyw Patricia Dankers, Henk M. Keizer, Ron M. A. Heeren, Ron M. Versteegen, Mgj Moniek Schmitz, Henk M. Janssen, Anne L. Bruinen

Publikováno v: Advanced Materials, 29(5):1604652, 1-8. Wiley-VCH Verlag
Advanced Materials, 29(5):1604652. Wiley-VCH Verlag

Selective surface modification reactions can be performed on additives that are supramolecularly incorporated into supramolecular materials. Hereby, processing of the material, that regularly requires harsh processing conditions (i.e., the use of org

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2ce34d74c5c150821e8875f036c5fc
https://research.tue.nl/nl/publications/57835fd3-e045-4996-bcda-1146d1eff03b

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