Zobrazeno 1 - 10
of 115
pro vyhledávání: '"A L, Zhuze"'
Autor:
Irina A. Zamulaeva, Kristina A. Churyukina, Olga N. Matchuk, Alexander A. Ivanov, Vyacheslav O. Saburov, Alexei L. Zhuze
Publikováno v:
AIMS Biophysics, Vol 7, Iss 4, Pp 339-361 (2020)
Purpose of the study was search for agents to eliminate the pool of cancer stem cells (CSCs) and increase their radiosensitivity among DNA minor groove binding ligands, synthetic dimeric bisbenzimidazoles of the DB(n) series, where n is the number of
Externí odkaz:
https://doaj.org/article/726d57155fe54677a355492ed4655814
Autor:
Albert F. Arutyunyan, Alexey A. Kostyukov, Vladislav A. Lushpa, Konstantin S. Mineev, Sergey P. Korolev, Marina B. Gottikh, Regina R. Klimova, Alla A. Kushch, Kseniya V. Kalabina, Olga Yu. Susova, Alexei L. Zhuze
Publikováno v:
Medicinal Chemistry Research. 32:587-599
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cb0738323ece8021db25222fe916717
https://doi.org/10.1007/s00044-023-03017-x
https://doi.org/10.1007/s00044-023-03017-x
Autor:
R. R. Klimova, E. D. Momotyuk, N. A. Demidova, Ya. Yu. Chernoryzh, V. S. Koval, A. A. Ivanov, A. L. Zhuze, A. A. Kushch
Publikováno v:
Вопросы вирусологии, Vol 62, Iss 4, Pp 162-168 (2017)
Antiviral activity of new AТ-specific fluorescent symmetric dimeric bisbenzimidazoles of DBА(n) series was assessed in the cell models of infections caused by type 1 herpes simplex virus (HSV1) and human cytomegalovirus (CMV). In DBA(n) molecules b
Externí odkaz:
https://doaj.org/article/75bb1d1002b7420b9eb9b0d2f8c5805f
Autor:
Svetlana V Kostyuk, Margarita A Kvasha, Daria A Khrabrova, Olga V Kirsanova, Elizaveta S Ershova, Elena M Malinovskaya, Natalia N Veiko, Alexander A Ivanov, Vasiliy S Koval, Alexei L Zhuze, Vadim H Tashlitsky, Pavel E Umriukhin, Sergey I Kutsev, Elizaveta S Gromova
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0189826 (2018)
Hypermethylation is observed in the promoter regions of suppressor genes in the tumor cancer cells. Reactivation of these genes by demethylation of their promoters is a prospective strategy of the anticancer therapy. Previous experiments have shown t
Externí odkaz:
https://doaj.org/article/05f28bd824684e1c93a67533e6846ab0
Autor:
Albert F. Arutyunyan, Alexey Kostyukov, Vladislav A. Lushpa, Konstantin S. Mineev, Sergey P. Korolev, Marina B. Gottikh, Regina R. Klimova, Alla A. Kushch, Kseniya V. Kalabina, Olga Yu. Susova, Alexei L. Zhuze
A new series of AT-specific minor groove DNA ligands (DB3P(n); n = 1,2,3,4) were synthesized and their spectral, biological and virological properties were investigated in water media. The variable length of methylene spacer in middle of molecule str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea2a6eaa9e10c9e360480e03959fcb78
https://doi.org/10.21203/rs.3.rs-2281778/v1
https://doi.org/10.21203/rs.3.rs-2281778/v1
Publikováno v:
Biophysics. 65:74-81
—This study aimed to determine how to eliminate and/or increase the radiosensitivity of a population of cancer stem cells that are responsible for radioresistance in malignant neoplasms. The single and combined effects of γ-radiation at a dose of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41ab17aad17a9817a241c0831a5b262f
https://doi.org/10.1134/s0006350920010030
https://doi.org/10.1134/s0006350920010030
Autor:
K.A. Churyukina, Alexander A. Ivanov, Vyacheslav O. Saburov, Irina A. Zamulaeva, Alexei L. Zhuze, Matchuk On
Publikováno v:
AIMS Biophysics, Vol 7, Iss 4, Pp 339-361 (2020)
Purpose of the study was search for agents to eliminate the pool of cancer stem cells (CSCs) and increase their radiosensitivity among DNA minor groove binding ligands, synthetic dimeric bisbenzimidazoles of the DB(n) series, where n is the number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b49b257d1b537d09238d76cdb3bc5bc
https://doi.org/10.3934/biophy.2020024
https://doi.org/10.3934/biophy.2020024
Autor:
Alexei L. Zhuze, Valentyn Oksenych, Koit Aasumets, Klara Krpina, Evandro Fei Fang, Eva Zusinaite, Denis E. Kainov, Ping Ji, Yahyah Aman, Magnar Bjørås, Pål Johansen, Albert F. Arutyunyan, Marit Bugge, Wei Wang, Caroline A. Heckman, Guofeng Lou, Hilde Lysvand, Kiira Gildemann, Andrii Bugai, Joachim M. Gerhold, Toril Holien, Yevhen Akimov, Anders Waage, Aleksandr Ianevski, Evgeny Kulesskiy, Daria Bulanova, Olga Yu. Susova
Publikováno v:
Cancers
Volume 12
Issue 6
Cancers, Vol 12, Iss 1694, p 1694 (2020)
Volume 12
Issue 6
Cancers, Vol 12, Iss 1694, p 1694 (2020)
Background: The evidence that pan-Bcl-2 or Bcl-xL-specific inhibitors prematurely kill virus-infected or RNA/DNA-transfected cells provides rationale for investigating these apoptotic inducers further. We hypothesized that not only invasive RNA or DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b14f7d0a1503ffc60e1aa98b8b69c2de
http://hdl.handle.net/10852/82462
http://hdl.handle.net/10852/82462
Autor:
Klimova Rr, N A Demidova, Ya. Yu. Chernoryzh, A. A. Ivanov, Vasiliy S. Koval, E. D. Momotyuk, Alexei L. Zhuze, Alla A. Kushch
Publikováno v:
Problems of Virology. 62:162-168
Antiviral activity of new AТ-specific fluorescent symmetric dimeric bisbenzimidazoles of DBА(n) series was assessed in the cell models of infections caused by type 1 herpes simplex virus (HSV1) and human cytomegalovirus (CMV). In DBA(n) molecules b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badea814438dc815c7abd1428d8d1ba7
https://doi.org/10.18821/0507-4088-2017-62-4-162-168
https://doi.org/10.18821/0507-4088-2017-62-4-162-168
Autor:
Yu. D. Nechipurenko, Alexei L. Zhuze, A. D. Guzaev, A. S. Krylov, M. V. Khodykov, Ya. V. Stirmanov, A. A. Ivanov
Publikováno v:
Biophysics. 62:356-360
Monomeric bis-benzimidazole (MB) is an analog of the Hoechst 33258 dye. The enthalpy and entropy of MB binding were evaluated by analyzing the calorimetric data on MB reverse titration with poly(dA) · poly(dT). A mathematical model was developed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23fe11c7c2269b1c0a49b6e60a64f4a9
https://doi.org/10.1134/s0006350917030137
https://doi.org/10.1134/s0006350917030137