Building a human lung from pluripotent stem cells to model respiratory viral infections

Autor: Declan L. Turner, Sahel Amoozadeh, Hannah Baric, Ed Stanley, Rhiannon B. Werder

Publikováno v: Respiratory Research, Vol 25, Iss 1, Pp 1-20 (2024)

Abstract To protect against the constant threat of inhaled pathogens, the lung is equipped with cellular defenders. In coordination with resident and recruited immune cells, this defence is initiated by the airway and alveolar epithelium following th

Externí odkaz: https://doaj.org/article/22082f76e19c436ab07516d01e31451b

Acute calcific tendinitis of the longus colli: A case report

Autor: Valery L. Turner, MD, Camila Martinez, MD, Judith Rocha, MD, Antonia Valenzuela, MD

Publikováno v: Radiology Case Reports, Vol 19, Iss 7, Pp 2650-2653 (2024)

Acute calcific longus colli tendinitis is a differential diagnosis of neck pain. Typical presentation consists in a triad of symptoms including acute onset neck pain, neck stiffness and odynophagia. Computed tomography (CT) is the gold standard for a

Externí odkaz: https://doaj.org/article/a1686ea8e5574c15973b941679ee9f5e

Evaluating soil erosion and runoff dynamics in a humid subtropic, low stream order, southern plains watershed from cultivation and solar farm development

Autor: Luis Mier-Valderrama, Julianna Leal, Humberto L. Perotto-Baldivieso, Brent Hedquist, Hector M. Menendez, Ambrose Anoruo, Benjamin L. Turner

Publikováno v: International Soil and Water Conservation Research, Vol 12, Iss 2, Pp 432-445 (2024)

Much work has been done to understand and improve soil and water conservation where agriculture has driven land use intensification. Less is known about soil- and water-related impacts from intensification driven by solar farming, especially at water

Externí odkaz: https://doaj.org/article/986c834b13bc4d5d98a6e1a847110f3c

Leveraging real-world data to predict cancer cachexia stage, quality of life, and survival in a racially and ethnically diverse multi-institutional cohort of treatment-naïve patients with pancreatic ductal adenocarcinoma

Autor: Jennifer B. Permuth, Margaret A. Park, Dung-Tsa Chen, Toni Basinski, Benjamin D. Powers, Clement K. Gwede, Kaleena B. Dezsi, Maria Gomez, Shraddha L. Vyas, Tiago Biachi, Elena M. Cortizas, Sylvia Crowder, Maria Genilo-Delgado, B.Lee Green, Anna Greene, Christopher Gregg, Sarah E. Hoffe, Kun Jiang, Bora Kim, Vanitha Vasudevan, Jeronimo Garcialopez De Llano, Anjana A. Menon, Qianxing Mo, Lina M. MorenoUrazan, Shaffer Mok, Nathan Parker, Sahana Rajasekhara, Ghulam Rasool, Andrew Sinnamon, Lauren Sparks, Paul A. Stewart, Kenneth Tardif, Alexandra F. Tassielli, Jamie K. Teer, Dan Viet Tran, Kea L. Turner, Susan T. Vadaparampil, Christopher J. Whelan, Wade G. Douglas, Vic Velanovich, Andreas Karachristos, Adrian Legaspi, Kenneth Meredith, Manual A. Molina-Vega, Kevin L. Huguet, Juan P. Arnoletti, Mark Bloomston, Jose Trevino, Nipun B. Merchant, Jose M. Pimiento, Pamela J. Hodul, Mokenge Malafa, Jason Fleming, Sarah M. Judge, Daniel K. Jeong, Andrew Judge

Publikováno v: Frontiers in Oncology, Vol 14 (2024)

IntroductionCancer-associated cachexia (CC) is a progressive syndrome characterized by unintentional weight loss, muscle atrophy, fatigue, and poor outcomes that affects most patients with pancreatic ductal adenocarcinoma (PDAC). The ability to ident

Externí odkaz: https://doaj.org/article/99b382aea6824ea3b6624e0a14f602fd

Changes in sick notes associated with COVID-19 from 2020 to 2022: a cohort study in 24 million primary care patients in OpenSAFELY-TPP

Autor: Andrew Steptoe, John Macleod, Daniel McCartney, Aziz Sheikh, Annie Herbert, Ben Goldacre, David Evans, Louise Jones, Sam Harper, Michael Green, Nicholas Timpson, John Wright, Liam Smeeth, Laurie A Tomlinson, Sinead Brophy, Kate Tilling, Andy Gibson, Paola Zaninotto, Stefan Neubauer, Yinghui Wei, Betty Raman, Chloe Park, Alun Hughes, Jonathan Sterne, Elena Lukaschuk, Stefan Piechnik, Angela Wood, Mark Green, Agnieszka Lemanska, Krishnan Bhaskaran, Kathryn Willan, Elsie Horne, Hannah Woodward, Ian Douglas, Andrew Wong, Andy Boyd, Harriet Forbes, Sinéad Langan, Nishi Chaturvedi, Tom Palmer, Kathryn Mansfield, Rachel Denholm, Emily Herrett, Kevin Wang, Bo Hou, Felix Greaves, Laura Sheard, Praveetha Patalay, Kishan Patel, Jessica Morley, Bang Zheng, Charlotte Booth, Spiros Denaxas, Brian MacKenna, Ruth E Costello, Jonathan Kennedy, William Hulme, Michael Parker, Geneviève Cezard, Syed A Shah, Amir Mehrkar, Peter Inglesby, Jonathan Cockburn, Laurie Tomlinson, John Parry, Frank Hester, Eoin McElroy, Amelia Green, Gillian Santorelli, Alisia Carnemolla, Richard Shaw, Samantha Ip, Venexia Walker, Emma L Turner, Richard Thomas, Rebecca Rhead, Archie Campbell, Ellen Thompson, Ruth Bowyer, Jane Maddock, Helen Curtis, Alex Walker, Olivia Hamilton, Rosie McEachan, Ellena Badrick, Stephen Smith, Richard Dobson, Stela McLachlan, Vanessa Ferreira, Vittal Katikireddi, Scott Walker, Lucy Teece, Simon Davy, John Tazare, Bettina Moltrecht, Theocharis Kromydas, Giorgio Di Gessa, Gareth Griffith, Viyaasan Mahalingasivam, Elizabeth Tunnicliffe, George Hickman, Tom Ward, Rebecca M Smith, Sam Parsons, Callum Stewart, Amos Folarin, Daniel Kopasker, Claire Steves, Louis Fisher, Sebastian C J Bacon, Lisa Hopcroft, Robin Y Park, Jon Massey, Iain Dillingham, Steven Maude, Wels Jacques, Linda Nab, Christopher Bates, Milan Wiedemann, Ruth Mitchell, Chao Fang, Fatima Almaghrabi, Jingmin Zhu, Lucy Bridges, Kurt Taylor, Colm Andrews, Jean Stafford, Nathan Cheetham, Sebastian CJ Bacon, Alicja Rapala, Robin Flaig, Andrea L Schaffer, Benjamin FC Butler-Cole, Liam Hart Ben Goldacre, Thomas O’Dwyer, Dylan Williams, Anika Knueppel, Katharine M Evans, Samantha Berman, Matthew Crane, Rebecca Whitehorn, Jacqui Oakley, Diane Foster, Kirsteen C Campbell, Alex Kwong, Ana Goncalves Soares, Renin Toms, Lizzie Huntley, Laura Fox, Rochelle Knight, Northstone Kate, Kanagaratnam Arun, Teri North, Marwa AL Arab, Jose IC Coronado, Arun S Karthikeyan, Ploubidis George, Bozena Wielgoszewska, Charis Bridger-Staatz, Paz Garcia, Maxim Freydin, Amy Roberts, Alex Walker Ben Goldacre, Jess Morley, Anoop Shah Richard Silverwood, Thomas Cowling, Kate Mansfield, Tiffany Yang, Tom Bolton, Alexia Sampri, Elena Rafeti, Robert Willans, Fiona Glen, Steve Sharp, Lee Hamill Howes, Lidia Nigrelli, Fintan McArdle, Chelsea Beckford, Yatharth Ranjan, Jd Carpentieri, Sarah Baz, John Kellas, Laura C Saunders, James M Wild, Peter Jezzard, Zeena-Britt Sanders, Lucy Finnigan, Milla Kibble, Francisco Perez-Reche, Dominik Piehlmaier, Edward Parker

Publikováno v: BMJ Open, Vol 14, Iss 7 (2024)

Objectives Long-term sickness absence from employment has negative consequences for the economy and can lead to widened health inequalities. Sick notes (also called ‘fit notes’) are issued by general practitioners when a person cannot work for he

Externí odkaz: https://doaj.org/article/1038a096d89044e5a8996a5c8992b394