Zobrazeno 1 - 10
of 16
pro vyhledávání: '"A L, Sollas"'
Publikováno v:
Journal of Neurophysiology. 90:2536-2547
Mossy fiber sprouting is a form of synaptic reorganization in the dentate gyrus that occurs in human temporal lobe epilepsy and animal models of epilepsy. The axons of dentate gyrus granule cells, called mossy fibers, develop collaterals that grow in
Publikováno v:
Neuroscience. 104:741-759
The clinical and basic literature suggest that hilar cells of the dentate gyrus are damaged after seizures, particularly prolonged and repetitive seizures. Of the cell types within the hilus, it appears that the mossy cell is one of the most vulnerab
Publikováno v:
The Journal of Neuroscience. 20:6144-6158
A group of neurons with the characteristics of dentate gyrus granule cells was found at the hilar/CA3 border several weeks after pilocarpine- or kainic acid-induced status epilepticus. Intracellular recordings from pilocarpine-treated rats showed tha
Publikováno v:
The Journal of Neuroscience. 19:5619-5631
This study examined the acute actions of brain-derived neurotrophic factor (BDNF) in the rat dentate gyrus after seizures, because previous studies have shown that BDNF has acute effects on dentate granule cell synaptic transmission, and other studie
Autor:
Robert S. Sloviter, Tara L. Rachinsky, Marc A. Dichter, Anne L. Sollas, David L. Martin, Jeffrey H. Goodman, Evelyn Dean
Publikováno v:
The Journal of Comparative Neurology. 373:593-618
The excitatory, glutamatergic granule cells of the hippocampal dentate gyrus are presumed to play central roles in normal learning and memory, and in the genesis of spontaneous seizure discharges that originate within the temporal lobe. In localizing
Publikováno v:
The Journal of Comparative Neurology. 366:516-533
Patients experiencing spontaneous seizures of temporal lobe origin often exhibit a shrunken hippocampus, which results from the loss of dentate granule cells, hilar neurons, and hippocampal pyramidal cells. Although experimental attempts to replicate
Publikováno v:
Brain Research. 682:227-230
Although adrenalectomy has been reported to induce a selective and sometimes nearly complete degeneration of hippocampal dentate granule cells, Azmitia and colleagues recently reported (Mol. Brain Res., 19 (1993) 328-332) that normal hippocampal stru
Publikováno v:
The Journal of Comparative Neurology. 330:324-336
The recent discovery that adrenalectomy results in hippocampal granule cell loss suggested that this phenomenon might be useful as a model of selective, experimentally controlled neuronal death possibly relevant to neurodegenerative disorders. This s
Publikováno v:
The Journal of comparative neurology. 454(4)
The rat dentate gyrus is usually described as relatively homogeneous. Here, we present anatomic and physiological data which demonstrate that there are striking differences between the supra- and infrapyramidal blades after status epilepticus and rec
Publikováno v:
Neuroscience. 111(1)
Although it is now established that neurogenesis of dentate gyrus granule cells increases after experimental seizures, little is currently known about the function of the new granule cells. One question is whether they become integrated into the netw