Zobrazeno 1 - 10
of 277
pro vyhledávání: '"A L, Mackey"'
Autor:
Malene Tangbjerg, Ann Damgaard, Anders Karlsen, Rene B. Svensson, Peter Schjerling, Miriam Gelabert‐Rebato, Stanislava Pankratova, Per Torp Sangild, Michael Kjaer, Abigail L. Mackey
Publikováno v:
Experimental Physiology, Vol 109, Iss 9, Pp 1529-1544 (2024)
Abstract Prematurity has physical consequences, such as lower birth weight, decreased muscle mass and increased risk of adult‐onset metabolic disease. Insulin‐like growth factor 1 (IGF‐1) has therapeutic potential to improve the growth and qual
Externí odkaz:
https://doaj.org/article/bc2c7b74345e491892345a49044227ac
Autor:
Casper Soendenbroe, Anders Karlsen, Rene B. Svensson, Michael Kjaer, Jesper L. Andersen, Abigail L. Mackey
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 1, Pp 306-318 (2024)
Abstract Background Age‐related loss of strength is disproportionally greater than the loss of mass, suggesting maladaptations in the neuro‐myo‐tendinous system. Myofibers are often misshaped in aged and diseased muscle, but systematic analyses
Externí odkaz:
https://doaj.org/article/421ada3c85714261a1e3b01109187bb9
Fusion of myofibre branches is a physiological feature of healthy human skeletal muscle regeneration
Autor:
Grith Højfeldt, Trent Sorenson, Alana Gonzales, Michael Kjaer, Jesper L. Andersen, Abigail L. Mackey
Publikováno v:
Skeletal Muscle, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Background The occurrence of hyperplasia, through myofibre splitting, remains a widely debated phenomenon. Structural alterations and fibre typing of skeletal muscle fibres, as seen during regeneration and in certain muscle diseases, can be
Externí odkaz:
https://doaj.org/article/847e2195c36545dea44866b96ddf27fe
Autor:
Jonathan J. Bjerre-Bastos, Casper Sejersen, Asger R. Bihlet, Niels H. Secher, Abigail L. Mackey, Carl-Christian Kitchen, Patryk Drobinski, Christian S. Thudium, Henning Bay Nielsen
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Introduction: Plasma volume (PV) changes in response to physical activity, possibly as a consequence of adrenergic activation. We estimated changes in PV in response to common exercise modalities; cycling and running as well as adrenaline infusion an
Externí odkaz:
https://doaj.org/article/6a5630ba440d4238b322350f3ab22d29
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-15 (2020)
Abstract Background Fibroblasts are the powerhouses responsible for the production and assembly of extracellular matrix (ECM). Their activity needs to be tightly controlled especially within the musculoskeletal system, where changes to ECM compositio
Externí odkaz:
https://doaj.org/article/4636fde944b349f9bb032054951e7975
Autor:
Anders Karlsen, Alba Gonzalez-Franquesa, Jens R. Jakobsen, Michael R. Krogsgaard, Manuel Koch, Michael Kjaer, Stefano Schiaffino, Abigail L. Mackey, Atul S. Deshmukh
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103836- (2022)
Summary: Proteomics analysis of skeletal muscle has recently progressed from whole muscle tissue to single myofibers. Here, we further focus on a specific myofiber domain crucial for force transmission from muscle to tendon, the myotendinous junction
Externí odkaz:
https://doaj.org/article/a69c469fe9fe4f3781380a18aacd2443
Autor:
Michal Tamáš, Stanislava Pankratova, Peter Schjerling, Casper Soendenbroe, Ching‐Yan Chloé Yeung, Cristian Pablo Pennisi, Jens R. Jakobsen, Michael R. Krogsgaard, Michael Kjaer, Abigail L. Mackey
Publikováno v:
Physiological Reports, Vol 9, Iss 21, Pp n/a-n/a (2021)
Abstract Insight into the bidirectional signaling between primary human myogenic cells and neurons is lacking. For this purpose, human myogenic cells were derived from the semitendinosus and gracilis muscles of five healthy individuals and co‐cultu
Externí odkaz:
https://doaj.org/article/74cb20f03038431e9c90762e3b383d57
Autor:
H. Michael Gach, PhD, Stacie L. Mackey, AAS, Sarah E. Hausman, BS, Danielle R. Jackson, BS, Tammie L. Benzinger, MD, PhD, Lauren Henke, MD, Lindsay A. Murphy, BS, Jamie L. Fluchel, BS, Bin Cai, PhD, Jacqueline E. Zoberi, PhD, Jose Garcia-Ramirez, MS, Sasa Mutic, PhD, Julie K. Schwarz, MD, PhD
Publikováno v:
Radiology Case Reports, Vol 14, Iss 5, Pp 634-638 (2019)
Obese patients constitute 40% of the adult population. MRIs of obese patients are typically challenging because of the effects of a large field of view on image quality and the increased risk of thermal burns from contact with the bore. In this case
Externí odkaz:
https://doaj.org/article/7b602a704bc84709a081826ae983646f
Autor:
John D. Lueck, Jae Seok Yoon, Alfredo Perales-Puchalt, Adam L. Mackey, Daniel T. Infield, Mark A. Behlke, Marshall R. Pope, David B. Weiner, William R. Skach, Paul B. McCray, Christopher A. Ahern
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Premature termination codon suppression therapy could be used to treat a range of genetic disorders. Here the authors present a high-throughput cell-based assay to identify anticodon engineered tRNAs with high suppression activity.
Externí odkaz:
https://doaj.org/article/407180d474f9434ca10313d5ef3ae933
Autor:
Simon M. Jensen, Cecilie J. L. Bechshøft, Mette F. Heisterberg, Peter Schjerling, Jesper L. Andersen, Michael Kjaer, Abigail L. Mackey
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The current model for repair of damaged tissue includes immune cells, mediating the progression from a pro-inflammatory to an anti-inflammatory environment. How this process changes with aging in human skeletal muscle under conditions of physiologica
Externí odkaz:
https://doaj.org/article/498f96ae55f445d5accaac5bb1bd789c