Zobrazeno 1 - 10
of 78
pro vyhledávání: '"A L, Kononenko"'
Autor:
A. Negrete-Hurtado, M. Overhoff, S. Bera, E. De Bruyckere, K. Schätzmüller, M. J. Kye, C. Qin, M. Lammers, V. Kondylis, I. Neundorf, N. L. Kononenko
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
In neurons, the microtubule cytoskeleton provides support and directionality of axons. Here, the authors report that microtubule dynamics in axons may be regulated by the autophagy proteins (ATGs) independently of their known role in autophagy.
Externí odkaz:
https://doaj.org/article/72accded71bb43fdaf15240e81ebccdb
Autor:
Chandan Sona, Yu-Te Yeh, Andreas Patsalos, Laszlo Halasz, Xin Yan, Natalia L. Kononenko, Laszlo Nagy, Matthew N. Poy
Publikováno v:
JCI Insight, Vol 7, Iss 6 (2022)
BACKGROUND Pathophysiology of type 1 diabetes (T1D) is illustrated by pancreatic islet infiltration of inflammatory lymphocytes, including CD8+ T cells; however, the molecular factors mediating their recruitment remain unknown. We hypothesized that s
Externí odkaz:
https://doaj.org/article/340a403c8bce4728982b8d90238639dd
Autor:
Natalia L. Kononenko, Gala A. Claßen, Marijn Kuijpers, Dmytro Puchkov, Tanja Maritzen, Aleksandra Tempes, Anna R. Malik, Agnieszka Skalecka, Sujoy Bera, Jacek Jaworski, Volker Haucke
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
The endocytic adaptor protein complex AP-2 is mostly known for its role in endocytosis and in synaptic vesicle reformation. Here the authors show that AP-2 also mediates retrograde transport of TrkB-containing autophagosomes in neurons; this process
Externí odkaz:
https://doaj.org/article/4d27649c1b8945efb76664268ba42b42
Autor:
Aaradhita Upadhyay, Seyyedmohsen Hosseinibarkooie, Svenja Schneider, Anna Kaczmarek, Laura Torres-Benito, Natalia Mendoza-Ferreira, Melina Overhoff, Roman Rombo, Vanessa Grysko, Min Jeong Kye, Natalia L. Kononenko, Brunhilde Wirth
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Neurocalcin delta (NCALD) is a brain-enriched neuronal calcium sensor and its reduction acts protective against spinal muscular atrophy (SMA). However, the physiological function of NCALD and implications of NCALD reduction are still elusive. Here, w
Externí odkaz:
https://doaj.org/article/35272ecbff7c41e6b8cfd4fe658f58e1
Publikováno v:
Agrobìologìâ. :41-48
The article presents a qualitative assessment and chemical component of sesame flour depending on the color. Enrichment of consumer products to increase the nutritional value of products intended for major populations is extremely important today. I
Autor:
Weiyi Chen, Oliver Mehlkop, Alexandra Scharn, Hendrik Nolte, Paul Klemm, Sinika Henschke, Lukas Steuernagel, Tamara Sotelo-Hitschfeld, Ecem Kaya, Claudia Maria Wunderlich, Thomas Langer, Natalia L. Kononenko, Patrick Giavalisco, Jens Claus Brüning
Publikováno v:
Cell Metabolism. 35:786-806.e13
Publikováno v:
Agrobìologìâ. :168-177
The article highlights a complex of studies and a comparative assessment of flour of various varieties and hybrids of chia and sorghum. It was found that, in terms of their chemical composition, these crops are advisable to use as raw materials for t
Publikováno v:
Journal of Neurochemistry. 157:263-296
Multiple aspects of neuronal physiology crucially depend on two cellular pathways, autophagy and endocytosis. During endocytosis, extracellular components either unbound or recognized by membrane-localized receptors (termed "cargo") become internaliz
Autor:
Natalia L. Kononenko, Volker Haucke
Publikováno v:
Neuroforum. 26:209-217
Communication in the central nervous system is based on the transmission of electrical signals at specialized junctions between nerve cells termed synapses. During chemical neurotransmission, tiny membrane spheres called synaptic vesicles that are pa
Autor:
Tayana Silva de Carvalho, Dirk M. Hermann, Santiago Camblor-Perujo, Kathy Keyvani, Tim Hagenacker, Eduardo H. Sanchez-Mendoza, Christoph Kleinschnitz, Sujoy Bera, Michael Fleischer, Linda-Isabell Schmitt, Natalia L. Kononenko, Luiza Martins Nascentes-Melo, Egor Dzyubenko, Markus Leo, Arne Herring
Publikováno v:
Molecular Neurobiology
Disrupted neuronal plasticity due to subtle inflammation is considered to play a fundamental role in the pathogenesis of major depressive disorder. Interferon-α (IFN-α) potentiates immune responses against viral pathogens that induce toll-like rece