Zobrazeno 1 - 10
of 807
pro vyhledávání: '"A L, Knutson"'
Autor:
Emmanuel M. Gabriel, Brian Necela, Deborah Bahr, Sneha Vivekanandhan, Barath Shreeder, Sanjay Bagaria, Keith L. Knutson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract In this study, we tested a novel approach of “repurposing” a biomarker typically associated with breast cancer for use in melanoma. HER2/neu is a well characterized biomarker in breast cancer for which effective anti-HER2/neu therapies a
Externí odkaz:
https://doaj.org/article/15cf9697167549baa914c2e9e20348c7
Autor:
Ana-Maria Sigarteu Chindris, Michael Rivera, Yaohua Ma, Asha Nair, Yi Liu, Xue Wang, Brian M. Necela, Jennifer M. Kachergus, John D. Casler, Christopher Brett, Ana M. Rivas Mejia, Victor J. Bernet, John A. Copland, Keith L. Knutson, E. Aubrey Thompson, Robert C. Smallridge
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionBRAFV600E mutation (BRAFmut) is common in papillary thyroid cancer (PTC), and most patients have an excellent outcome. However, a TERT-promoter mutation (pTERTmut) in the presence of BRAFmut (BRAFmutpTERTmut) has been demonstrated to conf
Externí odkaz:
https://doaj.org/article/4e35f5bc00f842e1a5836ad9a262635a
Autor:
Gabriel Anaya, Kelley Pettee Gabriel, Marie‐Pierre St‐Onge, Linda V. van Horn, Alfonso Alfini, Sylvia E. Badon, Carol Boushey, Alison Brown, Christopher M. Depner, Keith M. Diaz, Aiden Doherty, Erin E. Dooley, Dorothea Dumuid, Julio Fernandez‐Mendoza, Michael A. Grandner, Kirsten A. Herrick, Frank B. Hu, Kristen L. Knutson, Amanda Paluch, Charlotte A. Pratt, Jared P. Reis, Jennifer Schrack, Marissa M. Shams‐White, Diana Thomas, Katherine L. Tucker, Maya K. Vadiveloo, Dana L. Wolff‐Hughes, Yuling Hong
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 21 (2024)
The National Heart, Lung, and Blood Institute convened a virtual workshop in September 2022 to discuss “Optimal Instruments for Measurement of Diet, Physical Activity, and Sleep.” This report summarizes the proceedings, identifying current resear
Externí odkaz:
https://doaj.org/article/d0a0acfda58c4b23bc7939363a02be1e
Autor:
Roberto A. Leon-Ferre, Kaitlyn R. Whitaker, Vera J. Suman, Tanya Hoskin, Karthik V. Giridhar, Raymond M. Moore, Ahmad Al-Jarrad, Sarah A. McLaughlin, Donald W. Northfelt, Katie N. Hunt, Amy Lynn Conners, Ann Moyer, Jodi M. Carter, Krishna Kalari, Richard Weinshilboum, Liewei Wang, James N. Ingle, Keith L. Knutson, Stephen M. Ansell, Judy C. Boughey, Matthew P. Goetz, Jose C. Villasboas
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Background Tumor immune infiltration and peripheral blood immune signatures have prognostic and predictive value in breast cancer. Whether distinct peripheral blood immune phenotypes are associated with response to neoadjuvant chemotherapy (
Externí odkaz:
https://doaj.org/article/b975d37e612b41688982be8b1d8df388
Autor:
Jing Zhang, Aaron W. Aunins, Timothy L. King, Qian Cong, Jinhui Shen, Leina Song, Gregor W. Schuurman, Randy L. Knutson, Ralph Grundel, Jessica Hellmann, Nick V. Grishin
Publikováno v:
Ecology and Evolution, Vol 14, Iss 9, Pp n/a-n/a (2024)
Abstract The Karner blue butterfly, Plebejus (Lycaeides) samuelis, is an endangered North American climate change‐vulnerable species that has undergone substantial historical habitat loss and population decline. To better understand the species' ge
Externí odkaz:
https://doaj.org/article/6de3c02c5c414943a1b14ea0474af9d7
Autor:
Yi Lin, Yan W Asmann, Barath Shreeder, Keith L Knutson, Erik Jessen, Daniel P Wickland, Colton McNinch, Brian Necela
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Background Cancer neoantigens arise from protein-altering somatic mutations in tumor and rank among the most promising next-generation immuno-oncology agents when used in combination with immune checkpoint inhibitors. We previously developed a comput
Externí odkaz:
https://doaj.org/article/bf5610643ea74733ae707eb219999a5b
Autor:
Emmanuel M. Gabriel, Kulkaew Sukniam, Kyle Popp, Gabrielle Kowkabany, Harsheen K. Manaise, Kristopher Attwood, Anthony George, Qihui Zhai, Sanjay P. Bagaria, Keith L. Knutson, Joseph J. Skitzki, Matthew W. Robertson, Tri A. Dinh
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 4, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/8e2713ceecb14b7e8113cd3d0cc81638
Autor:
Jodi M. Carter, Saranya Chumsri, Douglas A. Hinerfeld, Yaohua Ma, Xue Wang, David Zahrieh, David W. Hillman, Kathleen S. Tenner, Jennifer M. Kachergus, Heather Ann Brauer, Sarah E. Warren, David Henderson, Ji Shi, Yi Liu, Heikki Joensuu, Henrik Lindman, Roberto A. Leon-Ferre, Judy C. Boughey, Minetta C. Liu, James N. Ingle, Krishna R. Kalari, Fergus J. Couch, Keith L. Knutson, Matthew P. Goetz, Edith A. Perez, E. Aubrey Thompson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract The utility of spatial immunobiomarker quantitation in prognostication and therapeutic prediction is actively being investigated in triple-negative breast cancer (TNBC). Here, with high-plex quantitative digital spatial profiling, we map and
Externí odkaz:
https://doaj.org/article/d5560e60b96445c4af2242dfe42eae7f
Autor:
Mandy L Pershing, Phyllis C Zee, Shaina J Alexandria, Kristen L. Knutson, Sabra Abbott, Sindhu Chiluka, Diana Chirinos, Aida Giachello, Niket Gupta, Katharine Harrington, Sarah S Rittner, Farzaneh Sorond, Mandy Wong, Thanh-Huyen T. Vu, Mercedes R. Carnethon
Publikováno v:
BMJ Open, Vol 13, Iss 11 (2023)
Introduction Cognitive dysfunction, a leading cause of mortality and morbidity in the USA and globally, has been shown to disproportionately affect the socioeconomically disadvantaged and those who identify as black or Hispanic/Latinx. Poor sleep is
Externí odkaz:
https://doaj.org/article/2735e2f7ce1848f9b0558d3473c5ddf2
Autor:
Yan Luo, Matthew S Block, Barath Shreeder, James W Jenkins, Huashan Shi, Purushottam Lamichhane, Kexun Zhou, Deborah A Bahr, Sophia Kurian, Katherine A Jones, Joshua I Daum, Navnita Dutta, Brian M Necela, Martin J Cannon, Keith L Knutson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 11 (2023)
Background Ovarian cancer (OC), a highly lethal cancer in women, has a 48% 5-year overall survival rate. Prior studies link the presence of IL-17 and Th17 T cells in the tumor microenvironment to improved survival in OC patients. To determine if Th17
Externí odkaz:
https://doaj.org/article/c7f089de207141e2ac20f5bd2a7c68ba