Zobrazeno 1 - 10
of 125
pro vyhledávání: '"A L, Glasebrook"'
Autor:
Joel Crespo, Yi Ting Koh, Ningjie Hu, Paul A Moore, Ezio Bonvini, Andrew L Glasebrook, Andrea P Martin, Robert J Benschop
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0245917 (2021)
Pre-clinical murine models are critical for translating drug candidates from the bench to the bedside. There is interest in better understanding how anti-human CD3 therapy works based on recent longitudinal studies of short-term administration. Altho
Externí odkaz:
https://doaj.org/article/284cea3843ea48808b3b32fa3cdf258b
Autor:
S.J. Demarest, Mathilde Poussin, Carmine Carpenito, Jason Manro, Xiufeng Wu, Shanshan Cao, F. Huang, Arlene Sereno, Andrew L. Glasebrook, Daniel J. Powell
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundBispecific T cell engagers represent the majority of bispecific antibodies (BsAbs) entering the clinic to treat metastatic cancer. The ability to apply these agents safely and efficaciously in the clinic, particularly for solid tumors, has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac991ed85fce38dde98d648d7e49b47
https://jitc.bmj.com/content/9/7/e002444.full
https://jitc.bmj.com/content/9/7/e002444.full
Autor:
Yi Ting Koh, Andrew L. Glasebrook, Ningjie Hu, Ezio Bonvini, Joel Crespo, Andrea P. Martin, Robert J. Benschop, Paul A. Moore
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0245917 (2021)
PLoS ONE
PLoS ONE
Pre-clinical murine models are critical for translating drug candidates from the bench to the bedside. There is interest in better understanding how anti-human CD3 therapy works based on recent longitudinal studies of short-term administration. Altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c97adf119aa161218f3600732511aa0
https://doaj.org/article/284cea3843ea48808b3b32fa3cdf258b
https://doaj.org/article/284cea3843ea48808b3b32fa3cdf258b
Autor:
Vanja Duric, Sophie Dutheil, Anja Koester, Masaaki Iwata, Dekun Song, Mounira Banasr, Takehiko Yamanashi, Kristie T. Ota, Xiaoyuan Li, Stevin H. Zorn, Fumika Sakaue, Kenneth A. Jones, Andrew L. Glasebrook, Koichi Kaneko, Ronald S. Duman, Nanxin Li, Gennady N. Smagin, Kurt Rasmussen
Publikováno v:
Biological Psychiatry. 80:12-22
Background The mechanisms underlying stress-induced inflammation that contribute to major depressive disorder are unknown. We examine the role of the adenosine triphosphate (ATP)/purinergic type 2X7 receptor (P2X7R) pathway and the NLRP3 (nucleotide-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1744552eabd5eacfae007399359283de
https://doi.org/10.1016/j.biopsych.2015.11.026
https://doi.org/10.1016/j.biopsych.2015.11.026
Autor:
H R MacDonald, Jean-Charles Cerottini, Andrew L. Glasebrook, Anne Kelso, Claude Bron, O. Acuto
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781468489613
Scopus-Elsevier
Scopus-Elsevier
The interaction between cytolytic T lymphocytes (CTL) and target cells is presumed to be mediated by antigen-specific receptors on the surface of CTL. One approach to the identification and characterization of such putative receptors is thus to make
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e2fac191cde386bd251d19b77b24f5
https://ora.ox.ac.uk/objects/uuid:6451959d-6b58-4e7b-bd3a-5bdd3ea61ec7
https://ora.ox.ac.uk/objects/uuid:6451959d-6b58-4e7b-bd3a-5bdd3ea61ec7
Autor:
Arlene Sereno, Brian Kuhlman, Xiufeng Wu, F. Huang, Micheal A. Batt, Steven M. Lewis, Andrew L. Glasebrook, Ricky Lieu, Cody Fine, Carina Torres, S.J. Demarest, J.R. Fitchett, Caroline Weldon
A myriad of innovative bispecific antibody (BsAb) platforms have been reported. Most require significant protein engineering to be viable from a development and manufacturing perspective. Single-chain variable fragments (scFvs) and diabodies that con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0588a462f07d25db3bbc907d734eae12
Autor:
Songqing Na, Robert J. Benschop, George E. Sandusky, Tonghai Zhang, Clint S. Schmidt, Jinqi Liu, Ho Yeong Song, Derek D. Yang, Andrew L. Glasebrook, Karen Mintze
Publikováno v:
The Journal of Experimental Medicine
Targeted disruption of death receptor (DR)6 results in enhanced CD4(+) T cell expansion and T helper cell type 2 differentiation after stimulation. Similar to T cells, DR6 is expressed on resting B cells but is down-regulated upon activation. We exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159df63dc4ad543e02831df8863641d9
http://europepmc.org/articles/PMC2193799
http://europepmc.org/articles/PMC2193799
Autor:
Songqing Na, Andrew L. Glasebrook, Neal W. Roehm, Chan Hsin S. Chang, Margaret M. Racke, Marian Mosior, Steve Kovacevic
Publikováno v:
Journal of Neurochemistry. 80:1039-1048
Activated caspase-3 is considered an important enzyme in the cell death pathway. To study the specific role of caspase-3 activation in neuronal cells, we generated a stable tetracycline-regulated SK-N-MC neuroblastoma cell line, which expressed a hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::261ac4caca38c0aec12d7376188b8cf1
https://doi.org/10.1046/j.0022-3042.2002.00787.x
https://doi.org/10.1046/j.0022-3042.2002.00787.x
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 69:37-44
Although controversy remains regarding direct effects of estrogen on bone, in vivo data clearly show that estrogens suppress bone turnover, resulting in decreased bone resorption and formation activity. Selective estrogen receptor modulators (SERMs),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bab7f35bd0d95c5df4c2e0e1619b0407
https://doi.org/10.1016/s0960-0760(98)00147-2
https://doi.org/10.1016/s0960-0760(98)00147-2