Zobrazeno 1 - 10
of 44
pro vyhledávání: '"A L, Germanova"'
Autor:
Natalia V. Belosludtseva, Alexey A Mosentsov, L. L. Pavlik, E. L. Germanova, L. D. Luk'yanova, Natalya V. Khmil, Yulia I. Kirova, Galina D. Mironova
Publikováno v:
Journal of Bioenergetics and Biomembranes. 51:329-340
The mitochondrial structure and the contents of subunits (NDUFV2, SDHA, Cyt b, COX1) of mitochondrial respiratory complexes I-IV as well as of the hypoxia-inducible factor (HIF-1α) in the brain cortex (BC) of rats with high resistance (HR) and low r
Publikováno v:
Bulletin of Experimental Biology and Medicine. 166:426-431
We performed a complex study of the dependence of immediate reaction of catalytic subunits in mitochondrial enzymes (NDUFV2, SDHA, Cyt b, COX1, and ATP5A) in rat cerebral cortex (the most hypoxia-sensitive tissue) on the severity and duration of hypo
Publikováno v:
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 120(1)
To study the ability of mexidol to induce cerebral mitochondriogenesis in the brain of young and aging rats.Expression level of marker proteins of cerebral mitochondriogenesis was evaluated during treatment with mexidol (20, 40, 100 mg/kg; 20 days; i
Publikováno v:
Bulletin of Experimental Biology and Medicine. 164:298-303
Hypoxia-induced immediate expression of transcription factor HIF-1α in the brain cortex is regulated by succinate produced in both the tricarbonic acid cycle and GABA shunt reactions and is induced by succinate-containing drugs. These facts prove th
Autor:
I. B. Mikheeva, L. D. Luk'yanova, L. L. Pavlik, Yu. I. Kirova, V. P. Berest, E. L. Germanova, Galina D. Mironova, Ya. M. Al’-Mugkhrabi
Publikováno v:
Bulletin of Experimental Biology and Medicine. 164:376-381
We performed ultrastructural study of cerebral cortex mitochondria in rats with different tolerance to oxygen deficiency (low resistant and highly resistant specimens). Low resistant rats were characterized by the prevalence of mitochondria with ligh
Autor:
Natalya V. Khmil, Galina D. Mironova, L. D. Luk'yanova, E. L. Germanova, M. I. Shigaeva, Lybov Pavlik, I. B. Mikheeva
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8636, p 8636 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences
Volume 22
Issue 16
This study was the first comprehensive investigation of the dependence of mitochondrial enzyme response (catalytic subunits of mitochondrial complexes (MC) I-V, including NDUFV2, SDHA, Cyt b, COX1 and ATP5A) and mitochondrial ultrastructure in the ra
Publikováno v:
Neurochemical Journal. 7:45-55
We studied the effects of single moderate hypobaric hypoxia (HBH, 10% O2, 60 min) on the central cholinergic systems. For this purpose, we determined the activity of the marker of cholinergic neurons choline acetyltransferase (ChAT) and the protein c
Publikováno v:
Bulletin of Experimental Biology and Medicine. 151:179-182
Hypobaric hypoxic preconditioning increased the resistance of low resistant and highly resistant rats to acute hypobaric hypoxia at a critical height. Intergroup differences in the resistance of rats to acute hypobaric hypoxia were not observed after
Publikováno v:
Bulletin of Experimental Biology and Medicine. 150:685-689
Different modes of hypoxic exposure led to phasic changes in activities of the complement system components in rats sensitive to hypoxia starting from the first minutes of the posthypoxic period and persisting for 24 h and longer. The direction of sh
Publikováno v:
Neurochemical Journal. 4:290-303
We studied the role of cholinergic systems of the rat brain in the mechanisms of acute response of the neocortex and hippocampus to acute hypobaric hypoxia. The activity of choline acetyltransferase and Na/K-ATPase and the protein content were measur