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pro vyhledávání: '"A L, Fletch"'
Publikováno v:
Comparative medicine. 50(5)
Spontaneous animal mutants affected by abnormal formation of myelin in the central nervous system (CNS) are useful in studies on myelinogenesis and remyelination leading to better understanding of cellular and molecular interactions involved in myeli
Publikováno v:
Journal of neurocytology. 27(8)
The Long Evans shaker (les) rat is a recently identified CNS myelin mutant with an autosomal recessive mode of inheritance. Although scattered myelin sheaths are present in some areas of the CNS, most notably the ventral spinal cord in the young neon
Autor:
Andrew L. Fletch, Kathleen H. Delaney, Ian D. Duncan, Jacek M. Kwiecien, Brian D. Goetz, Lawrence T. O'Connor
Our understanding of myelination has been greatly enhanced via the study of spontaneous mutants that harbor a defect in a gene encoding one of the major myelin proteins (myelin mutants). In this study, we describe a unique genetic defect in a new mye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a88dc95c4780a1a143f7c13b636a90cf
https://europepmc.org/articles/PMC6782241/
https://europepmc.org/articles/PMC6782241/
Publikováno v:
Laboratory animal science. 45(5)
Tremors were observed in 15 Long Evans rats beginning at 10 to 12 days of age. These were followed by progressively worsening ataxia, hind limb paresis, episodes of immobility, and seizures by 5 to 14 weeks. Gross lesions were not observed at necrops
Publikováno v:
JNCI: Journal of the National Cancer Institute. 56:1063-1067
7,12-Dimethylbenz[a]anthracene (DMBA) administered iv to pregnant Sparague-Dawley rats produced cerebellar malfunction in at least 10% of the offspring. The underlying morphologic basis of the cerebellar symptomatology was found in maldevelopment of
Autor:
Lars Karstad, A. L. Fletch
Publikováno v:
Bulletin of the Wildlife Disease Association. 4:9-11
Publikováno v:
Journal of the National Cancer Institute. 56(5)
7,12-Dimethylbenz[a]anthracene (DMBA) administered iv to pregnant Sparague-Dawley rats produced cerebellar malfunction in at least 10% of the offspring. The underlying morphologic basis of the cerebellar symptomatology was found in maldevelopment of
Publikováno v:
Bibliotheca anatomica. 11
Autor:
A L, Fletch
Publikováno v:
The Canadian veterinary journal = La revue veterinaire canadienne. 10(3)
Autor:
A L, Fletch, L H, Karstad
Publikováno v:
Canadian journal of comparative medicine : Revue canadienne de medecine comparee. 35(3)
Observations were made of clinical signs, gross and microscopic lesions in white-tailed deer infected with epizootic hemorrhagic disease (EHD) virus. Typically, animals became weak and lethargic and developed hyperemia of the oral and nasal mucosa, t